tradingkey.logo

Centessa Pharmaceuticals PLC

CNTA
22.120USD
-0.715-3.13%
Close 11/07, 16:00ETQuotes delayed by 15 min
2.97BMarket Cap
LossP/E TTM

Centessa Pharmaceuticals PLC

22.120
-0.715-3.13%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Centessa Pharmaceuticals PLC

Currency: USD Updated: 2025-11-07

Key Insights

The company's fundamentals are relatively healthy. Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Buy. Despite an average stock market performance, the company shows strong fundamentals and technicals. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Centessa Pharmaceuticals PLC's Score

Industry at a Glance

Industry Ranking
6 / 407
Overall Ranking
56 / 4614
Industry
Biotechnology & Medical Research

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 15 analysts
Buy
Current Rating
33.154
Target Price
+45.19%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Centessa Pharmaceuticals PLC Highlights

StrengthsRisks
Centessa Pharmaceuticals plc is a United Kingdom-based clinical-stage pharmaceutical company. Its advanced programs include a hemophilia program, an orexin agonist program for the treatment of narcolepsy and other sleep-wake disorders, and an immuno-oncology program focused on its LockBody technology platform. SerpinPC, its advanced product candidate, is an investigational, potentially first-in-class subcutaneously administered novel inhibitor of activated protein C for hemophilia. Its Orexin Receptor 2 (OX2R) Agonist Program includes ORX750, which is an investigational, orally administered, selective OX2R agonist designed to directly target the underlying pathophysiology of orexin neuron loss in narcolepsy type 1 and to address sleep-wake disorders with normal orexin levels such as narcolepsy type 2 and idiopathic hypersomnia. It is also exploring follow-up orexin agonists for potential expansion opportunities into a range of sleep-wake disorders and broader neurological indications.
Undervalued
The company’s latest PE is -11.66, at a low 3-year percentile range.
Institutional Selling
The latest institutional holdings are 129.59M shares, decreasing 10.35% quarter-over-quarter.
Held by Steven Cohen
Star Investor Steven Cohen holds 2.59M shares of this stock.

Financial Health

Currency: USD Updated: 2025-11-07

The company's current financial score is 8.37, which is higher than the Biotechnology & Medical Research industry's average of 6.92. Its financial status is stable, and its operating efficiency is high.

Score

Industry at a Glance

Previous score
8.37
Change
0

Financials

6.54

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
No Data

Quality of Earnings

9.32

Operational Efficiency

10.00

Growth Potential

8.53

Shareholder Returns

7.44

Centessa Pharmaceuticals PLC's Company Valuation

Currency: USD Updated: 2025-11-07

The company’s current valuation score is 6.80, which is lower than the Biotechnology & Medical Research industry's average of 7.05. Its current P/E ratio is -11.66, which is -88.78% below the recent high of -1.31 and -15.80% above the recent low of -13.51.

Score

Industry at a Glance

Previous score
6.80
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 6/407
No Data

Earnings Forecast

Currency: USD Updated: 2025-11-07

The company’s current earnings forecast score is 8.67, which is higher than the Biotechnology & Medical Research industry's average of 8.00. The average price target for Centessa Pharmaceuticals PLC is 33.00, with a high of 40.00 and a low of 27.00.

Score

Industry at a Glance

Previous score
8.67
Change
0

Support & Resistance

No Data

Analyst Rating

Based on 15 analysts
Buy
Current Rating
33.154
Target Price
+45.19%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

521
Total
6
Median
6
Average
Company name
Ratings
Analysts
Centessa Pharmaceuticals PLC
CNTA
15
CRISPR Therapeutics AG
CRSP
30
Intellia Therapeutics Inc
NTLA
25
IQVIA Holdings Inc
IQV
25
Ionis Pharmaceuticals Inc
IONS
25
argenx SE
ARGX
25
1
2
3
...
104

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-11-07

The company’s current price momentum score is 9.07, which is higher than the Biotechnology & Medical Research industry's average of 6.46. Sideways: Currently, the stock price is trading between the resistance level at 26.01 and the support level at 17.64, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
9.26
Change
-0.19

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(2)
Neutral(3)
Buy(1)
Indicators
Value
Direction
MACD(12,26,9)
-0.585
Neutral
RSI(14)
42.907
Neutral
STOCH(KDJ)(9,3,3)
61.526
Neutral
ATR(14)
1.626
High Vlolatility
CCI(14)
-106.543
Sell
Williams %R
39.427
Buy
TRIX(12,20)
0.224
Sell
StochRSI(14)
0.000
Oversold
Moving Average
Sell(4)
Neutral(0)
Buy(2)
Indicators
Value
Direction
MA5
23.031
Sell
MA10
23.782
Sell
MA20
23.413
Sell
MA50
22.297
Sell
MA100
18.933
Buy
MA200
16.652
Buy

Institutional Confidence

Currency: USD Updated: 2025-11-07

The company’s current institutional recognition score is 10.00, which is higher than the Biotechnology & Medical Research industry's average of 5.16. The latest institutional shareholding proportion is 96.68%, representing a quarter-over-quarter decrease of 3.40%. The largest institutional shareholder is PRFDX, holding a total of 5.91M shares, representing 4.41% of shares outstanding, with 8.95% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
Medicxi Ventures (UK) LLP
19.96M
--
Index Ventures SA
9.96M
--
General Atlantic LLC
9.68M
--
Adage Capital Management, L.P.
8.40M
+20.84%
Janus Henderson Investors
6.53M
+10.30%
T. Rowe Price Associates, Inc.
Star Investors
5.91M
+10.59%
Avoro Capital Advisors LLC
5.00M
+23.46%
Farallon Capital Management, L.L.C.
4.53M
+4.50%
First Light Asset Management, LLC
4.29M
-11.91%
VV Manager LLC
3.93M
--
1
2

Risk Assessment

Currency: USD Updated: 2025-11-07

The company’s current risk assessment score is 6.03, which is higher than the Biotechnology & Medical Research industry's average of 3.47. The company's beta value is 1.58. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets.

Score

Industry at a Glance

Previous score
6.03
Change
0
Beta vs S&P 500 index
1.58
VaR
--
240-Day Maximum Drawdown
+43.72%
240-Day Volatility
+78.37%

Return

Best Daily Return
60 days
+15.64%
120 days
+15.64%
5 years
--
Worst Daily Return
60 days
-7.87%
120 days
-7.87%
5 years
--
Sharpe Ratio
60 days
+1.99
120 days
+2.34
5 years
--

Risk Assessment

Maximum Drawdown
240 days
+43.72%
3 years
+43.72%
5 years
--
Return-to-Drawdown Ratio
240 days
+0.49
3 years
+4.38
5 years
--
Skewness
240 days
+0.43
3 years
+0.39
5 years
--

Volatility

Realised Volatility
240 days
+78.37%
5 years
--
Standardised True Range
240 days
+4.63%
5 years
--
Downside Risk-Adjusted Return
120 days
+452.22%
240 days
+452.22%
Maximum Daily Upside Volatility
60 days
+53.19%
Maximum Daily Downside Volatility
60 days
+64.41%

Liquidity

Average Turnover Rate
60 days
+0.83%
120 days
+0.75%
5 years
--
Turnover Deviation
20 days
+60.72%
60 days
+76.35%
120 days
+60.06%

Peer Comparison

Biotechnology & Medical Research
Centessa Pharmaceuticals PLC
Centessa Pharmaceuticals PLC
CNTA
8.26 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.60 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Insmed Inc
Insmed Inc
INSM
8.52 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.51 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
MDGL
8.45 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Dynavax Technologies Corp
Dynavax Technologies Corp
DVAX
8.37 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more
KeyAI