tradingkey.logo

Centessa Pharmaceuticals PLC

CNTA
23.490USD
-0.050-0.21%
Close 02/06, 16:00ETQuotes delayed by 15 min
3.16BMarket Cap
LossP/E TTM

Centessa Pharmaceuticals PLC

23.490
-0.050-0.21%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Centessa Pharmaceuticals PLC

Currency: USD Updated: 2026-02-06

Key Insights

Centessa Pharmaceuticals PLC's fundamentals are relatively healthy, with an industry-leading ESG disclosure.and its growth potential is high.Its valuation is considered fairly valued, ranking 20 out of 392 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 39.62.In the medium term, the stock price is expected to remain stable.Despite an average stock market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Centessa Pharmaceuticals PLC's Score

Industry at a Glance

Industry Ranking
20 / 392
Overall Ranking
110 / 4521
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Negative

Centessa Pharmaceuticals PLC Highlights

StrengthsRisks
Centessa Pharmaceuticals plc is a clinical-stage pharmaceutical company. The Company is developing a new class of potential therapies within its orexin receptor 2 (OX2R) agonist program for the treatment of excessive daytime sleepiness (EDS), impaired attention, cognitive deficits, fatigue and other symptoms across neurological, neurodegenerative and neuropsychiatric disorders. It also has an early-stage immuno-oncology program focused on its LockBody technology platform. Its OX2R agonist pipeline includes ORX750, its advanced OX2R agonist development candidate, and ORX142, ORX489 and OX2R agonists in preclinical development. Its ORX750, an investigational, orally administered, highly potent and selective OX2R agonist, is in a Phase IIa study of participants with narcolepsy type 1 (NT1), NT2 and idiopathic hypersomnia (IH). ORX142 is the second OX2R agonist development candidate being advanced for the treatment of neurological and neurodegenerative disorders and other symptoms.
Undervalued
The company’s latest PE is -12.39, at a low 3-year percentile range.
Institutional Buying
The latest institutional holdings are 133.92M shares, increasing 0.01% quarter-over-quarter.
Held by Invesco
Star Investor Invesco holds 5.38K shares of this stock.

Analyst Rating

Based on 15 analysts
Buy
Current Rating
39.615
Target Price
+68.29%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-02-06

The current financial score of Centessa Pharmaceuticals PLC is 8.37, ranking 46 out of 392 in the Biotechnology & Medical Research industry. Its financial status is stable, and its operating efficiency is high.

Score

Industry at a Glance

Previous score
7.70
Change
0.67

Financials

6.54

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

9.32

Operational Efficiency

10.00

Growth Potential

8.53

Shareholder Returns

7.44

Centessa Pharmaceuticals PLC's Company Valuation

Currency: USD Updated: 2026-02-06

The current valuation score of Centessa Pharmaceuticals PLC is 6.80, ranking 220 out of 392 in the Biotechnology & Medical Research industry. Its current P/E ratio is -12.39, which is -89.43% below the recent high of -1.31 and -27.33% above the recent low of -15.77.

Score

Industry at a Glance

Previous score
6.80
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 20/392
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-02-06

The current earnings forecast score of Centessa Pharmaceuticals PLC is 8.67, ranking 70 out of 392 in the Biotechnology & Medical Research industry. The average price target is 36.00, with a high of 52.00 and a low of 30.00.

Score

Industry at a Glance

Previous score
8.67
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 15 analysts
Buy
Current Rating
39.615
Target Price
+68.29%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

542
Total
6
Median
6
Average
Company name
Ratings
Analysts
Centessa Pharmaceuticals PLC
CNTA
15
CRISPR Therapeutics AG
CRSP
29
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Beigene Ltd
ONC
24
Intellia Therapeutics Inc
NTLA
24
1
2
3
...
109

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-02-06

The current price momentum score of Centessa Pharmaceuticals PLC is 7.33, ranking 80 out of 392 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 26.25 and the support level at 21.12, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
7.37
Change
-0.04

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(3)
Neutral(3)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
0.047
Neutral
RSI(14)
42.960
Neutral
STOCH(KDJ)(9,3,3)
17.111
Sell
ATR(14)
1.491
High Vlolatility
CCI(14)
-70.307
Neutral
Williams %R
61.209
Sell
TRIX(12,20)
0.118
Sell
StochRSI(14)
0.000
Oversold
Moving Average
Sell(5)
Neutral(0)
Buy(1)
Indicators
Value
Direction
MA5
24.540
Sell
MA10
24.912
Sell
MA20
23.927
Sell
MA50
25.385
Sell
MA100
24.682
Sell
MA200
19.779
Buy

Institutional Confidence

Currency: USD Updated: 2026-02-06

The current institutional shareholding score of Centessa Pharmaceuticals PLC is 10.00, ranking 1 out of 392 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 99.37%, representing a quarter-over-quarter decrease of 8.92%. The largest institutional shareholder is PRFDX, holding a total of 4.80M shares, representing 3.29% of shares outstanding, with 17.74% decrease in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Medicxi Ventures (UK) LLP
19.96M
--
Avoro Capital Advisors LLC
10.81M
+116.16%
Adage Capital Management, L.P.
10.04M
+19.42%
Index Ventures SA
9.96M
--
General Atlantic LLC
7.37M
-23.91%
Fidelity Management & Research Company LLC
6.24M
+63.08%
Janus Henderson Investors
5.41M
-17.21%
T. Rowe Price Associates, Inc.
Star Investors
4.80M
-18.69%
Farallon Capital Management, L.L.C.
4.33M
-4.37%
First Light Asset Management, LLC
3.64M
-15.32%
1
2

Risk Assessment

Currency: USD Updated: 2026-02-06

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Centessa Pharmaceuticals PLC is 5.10, ranking 56 out of 392 in the Biotechnology & Medical Research industry. The company's beta value is 1.58. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
5.10
Change
0
Beta vs S&P 500 index
1.58
VaR
--
240-Day Maximum Drawdown
+37.73%
240-Day Volatility
+75.12%

Return

Best Daily Return
60 days
+18.46%
120 days
+18.46%
5 years
--
Worst Daily Return
60 days
-8.08%
120 days
-8.08%
5 years
--
Sharpe Ratio
60 days
+0.49
120 days
+1.40
5 years
--

Risk Assessment

Maximum Drawdown
240 days
+37.73%
3 years
+43.72%
5 years
--
Return-to-Drawdown Ratio
240 days
+1.33
3 years
+4.01
5 years
--
Skewness
240 days
+0.84
3 years
+0.49
5 years
--

Volatility

Realised Volatility
240 days
+75.12%
5 years
--
Standardised True Range
240 days
+4.59%
5 years
--
Downside Risk-Adjusted Return
120 days
+280.64%
240 days
+280.64%
Maximum Daily Upside Volatility
60 days
+47.48%
Maximum Daily Downside Volatility
60 days
+31.72%

Liquidity

Average Turnover Rate
60 days
+0.83%
120 days
+0.75%
5 years
--
Turnover Deviation
20 days
+60.72%
60 days
+76.35%
120 days
+60.06%

Peer Comparison

Biotechnology & Medical Research
Centessa Pharmaceuticals PLC
Centessa Pharmaceuticals PLC
CNTA
7.82 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.60 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.53 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ionis Pharmaceuticals Inc
Ionis Pharmaceuticals Inc
IONS
8.38 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.37 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.17 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more
KeyAI