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Centessa Pharmaceuticals PLC

CNTA
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39.600USD
-0.010-0.03%
Market hours ETQuotes delayed by 15 min
5.91BMarket Cap
LossP/E TTM

Centessa Pharmaceuticals PLC

39.600
-0.010-0.03%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Centessa Pharmaceuticals PLC

Currency: USD Updated: 2026-05-12

Key Insights

Centessa Pharmaceuticals PLC's fundamentals are relatively healthy, with an industry-leading ESG disclosure.and its growth potential is high.Its valuation is considered fairly valued, ranking 47 out of 383 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Hold, with the highest price target at 44.00.In the medium term, the stock price is expected to trend up.Despite an average stock market performance over the past month, the company shows strong fundamentals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Centessa Pharmaceuticals PLC's Score

Industry at a Glance

Industry Ranking
47 / 383
Overall Ranking
153 / 4490
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Negative

Centessa Pharmaceuticals PLC Highlights

StrengthsRisks
Centessa Pharmaceuticals plc is a clinical-stage pharmaceutical company. The Company is developing a new class of potential therapies within its orexin receptor 2 (OX2R) agonist program for the treatment of excessive daytime sleepiness (EDS), impaired attention, cognitive deficits, fatigue and other symptoms across neurological, neurodegenerative and neuropsychiatric disorders. It also has an early-stage immuno-oncology program focused on its LockBody technology platform. Its OX2R agonist pipeline includes ORX750, its advanced OX2R agonist development candidate, and ORX142, ORX489 and OX2R agonists in preclinical development. Its ORX750, an investigational, orally administered, highly potent and selective OX2R agonist, is in a Phase IIa study of participants with narcolepsy type 1 (NT1), NT2 and idiopathic hypersomnia (IH). ORX142 is the second OX2R agonist development candidate being advanced for the treatment of neurological and neurodegenerative disorders and other symptoms.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 118.88% year-on-year.
Growing
The company is in a growing phase, with the latest annual income totaling USD 15.00M.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 15.00M.
Undervalued
The company’s latest PE is -22.31, at a low 3-year percentile range.
Institutional Buying
The latest institutional holdings are 150.25M shares, increasing 7.40% quarter-over-quarter.
Held by Invesco
Star Investor Invesco holds 7.03K shares of this stock.
Lower Market Activity
The company has less investor interest, with a 20-day turnover ratio of 0.75.

Analyst Rating

Based on 13 analysts
Hold
Current Rating
44.000
Target Price
+11.14%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-05-12

The current financial score of Centessa Pharmaceuticals PLC is 8.37, ranking 38 out of 383 in the Biotechnology & Medical Research industry. Its financial status is stable, and its operating efficiency is high. Its latest quarterly revenue reached 0.00, representing a year-over-year decrease of 100.00%, while its net profit experienced a year-over-year decrease of 203.20%.

Score

Industry at a Glance

Previous score
8.37
Change
0

Financials

6.54

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

9.32

Operational Efficiency

10.00

Growth Potential

8.53

Shareholder Returns

7.44

Centessa Pharmaceuticals PLC's Company Valuation

Currency: USD Updated: 2026-05-12

The current valuation score of Centessa Pharmaceuticals PLC is 6.80, ranking 210 out of 383 in the Biotechnology & Medical Research industry. Its current P/E ratio is -22.31, which is -94.13% below the recent high of -1.31 and -22.42% above the recent low of -27.32.

Score

Industry at a Glance

Previous score
6.80
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 47/383
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-05-12

The current earnings forecast score of Centessa Pharmaceuticals PLC is 7.54, ranking 290 out of 383 in the Biotechnology & Medical Research industry. The average price target is 36.00, with a high of 52.00 and a low of 30.00.

Score

Industry at a Glance

Previous score
7.54
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 13 analysts
Hold
Current Rating
44.000
Target Price
+11.14%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

554
Total
5
Median
6
Average
Company name
Ratings
Analysts
Centessa Pharmaceuticals PLC
CNTA
13
CRISPR Therapeutics AG
CRSP
29
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Beigene Ltd
ONC
26
Ionis Pharmaceuticals Inc
IONS
25
1
2
3
...
111

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-05-12

The current price momentum score of Centessa Pharmaceuticals PLC is 5.79, ranking 305 out of 383 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 39.84 and the support level at 39.37, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
6.01
Change
-0.22

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(1)
Neutral(4)
Buy(2)
Indicators
Value
Direction
MACD(12,26,9)
-0.781
Neutral
RSI(14)
72.501
Buy
STOCH(KDJ)(9,3,3)
51.882
Neutral
ATR(14)
0.150
High Vlolatility
CCI(14)
47.109
Neutral
Williams %R
46.875
Neutral
TRIX(12,20)
0.420
Sell
StochRSI(14)
43.858
Buy
Moving Average
Sell(0)
Neutral(0)
Buy(6)
Indicators
Value
Direction
MA5
39.600
Buy
MA10
39.581
Buy
MA20
39.547
Buy
MA50
34.742
Buy
MA100
29.588
Buy
MA200
25.995
Buy

Institutional Confidence

Currency: USD Updated: 2026-05-12

The current institutional shareholding score of Centessa Pharmaceuticals PLC is 10.00, ranking 1 out of 383 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 97.10%, representing a quarter-over-quarter decrease of 2.28%. The largest institutional shareholder is PRFDX, holding a total of 3.93M shares, representing 2.54% of shares outstanding, with 36.53% decrease in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Medicxi Ventures (UK) LLP
19.96M
--
Avoro Capital Advisors LLC
14.56M
+34.67%
Adage Capital Management, L.P.
11.28M
+12.42%
Index Ventures SA
9.96M
--
Fidelity Management & Research Company LLC
8.06M
+29.16%
General Atlantic LLC
6.12M
-16.96%
Farallon Capital Management, L.L.C.
5.38M
+24.14%
TCG Crossover Management, LLC
4.29M
+36.67%
Janus Henderson Investors
4.09M
-24.31%
1
2

Risk Assessment

Currency: USD Updated: 2026-05-12

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Centessa Pharmaceuticals PLC is 5.10, ranking 53 out of 383 in the Biotechnology & Medical Research industry. The company's beta value is 1.13. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
5.10
Change
0
Beta vs S&P 500 index
1.13
VaR
+6.52%
240-Day Maximum Drawdown
+26.38%
240-Day Volatility
+75.05%

Return

Best Daily Return
60 days
+44.02%
120 days
+44.02%
5 years
+44.02%
Worst Daily Return
60 days
-4.52%
120 days
-8.08%
5 years
-27.78%
Sharpe Ratio
60 days
+2.50
120 days
+1.33
5 years
+0.54

Risk Assessment

Maximum Drawdown
240 days
+26.38%
3 years
+43.72%
5 years
+86.89%
Return-to-Drawdown Ratio
240 days
+7.80
3 years
+4.16
5 years
+0.21
Skewness
240 days
+4.88
3 years
+1.74
5 years
+0.81

Volatility

Realised Volatility
240 days
+75.05%
5 years
+90.95%
Standardised True Range
240 days
+2.77%
5 years
+2.05%
Downside Risk-Adjusted Return
120 days
+383.14%
240 days
+383.14%
Maximum Daily Upside Volatility
60 days
+97.37%
Maximum Daily Downside Volatility
60 days
+96.25%

Liquidity

Average Turnover Rate
60 days
+1.98%
120 days
+1.56%
5 years
--
Turnover Deviation
20 days
+75.04%
60 days
+121.81%
120 days
+75.06%

Peer Comparison

Biotechnology & Medical Research
Centessa Pharmaceuticals PLC
Centessa Pharmaceuticals PLC
CNTA
7.29 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.75 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.60 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.54 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Exelixis Inc
Exelixis Inc
EXEL
8.45 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.45 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
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