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Bicycle Therapeutics PLC

BCYC
5.660USD
+0.350+6.59%
Close 02/06, 16:00ETQuotes delayed by 15 min
282.26MMarket Cap
LossP/E TTM

Bicycle Therapeutics PLC

5.660
+0.350+6.59%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Bicycle Therapeutics PLC

Currency: USD Updated: 2026-02-06

Key Insights

Bicycle Therapeutics PLC's fundamentals are relatively very healthy, with an industry-leading ESG disclosure.and its growth potential is high.Its valuation is considered fairly valued, ranking 51 out of 392 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 20.17.In the medium term, the stock price is expected to trend down.Despite a weak stock market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Bicycle Therapeutics PLC's Score

Industry at a Glance

Industry Ranking
51 / 392
Overall Ranking
158 / 4521
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Neutral

Bicycle Therapeutics PLC Highlights

StrengthsRisks
Bicycle Therapeutics plc is a United Kingdom-based clinical-stage biopharmaceutical company developing a class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. The Company is evaluating zelenectide pevedotin, a Bicycle Toxin Conjugate (BTC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BTC targeting EphA2, a historically undruggable target, and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in Company-sponsored clinical trials. Additionally, the Company is developing Bicycle Radio Conjugates (BRC) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle technology to develop therapies for diseases beyond oncology.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 143.90% year-on-year.
Growing
The company is in a growing phase, with the latest annual income totaling USD 35.27M.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 35.27M.
Overvalued
The company’s latest PE is -1.56, at a high 3-year percentile range.
Institutional Buying
The latest institutional holdings are 39.22M shares, increasing 0.08% quarter-over-quarter.
Held by Invesco
Star Investor Invesco holds 10.52K shares of this stock.

Analyst Rating

Based on 14 analysts
Buy
Current Rating
20.167
Target Price
+279.79%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-02-06

The current financial score of Bicycle Therapeutics PLC is 7.79, ranking 76 out of 392 in the Biotechnology & Medical Research industry. Its financial status is robust, and its operating efficiency is low. Its latest quarterly revenue reached 11.73M, representing a year-over-year increase of 338.49%, while its net profit experienced a year-over-year increase of 16.33%.

Score

Industry at a Glance

Previous score
7.79
Change
0

Financials

9.91

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

8.38

Operational Efficiency

3.12

Growth Potential

10.00

Shareholder Returns

7.54

Bicycle Therapeutics PLC's Company Valuation

Currency: USD Updated: 2026-02-06

The current valuation score of Bicycle Therapeutics PLC is 7.66, ranking 93 out of 392 in the Biotechnology & Medical Research industry. Its current P/E ratio is -1.56, which is -6.18% below the recent high of -1.46 and -438.91% above the recent low of -8.41.

Score

Industry at a Glance

Previous score
7.66
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 51/392
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-02-06

The current earnings forecast score of Bicycle Therapeutics PLC is 7.86, ranking 264 out of 392 in the Biotechnology & Medical Research industry. The average price target is 16.00, with a high of 44.00 and a low of 6.00.

Score

Industry at a Glance

Previous score
7.86
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 14 analysts
Buy
Current Rating
20.167
Target Price
+279.79%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

542
Total
6
Median
6
Average
Company name
Ratings
Analysts
Bicycle Therapeutics PLC
BCYC
14
CRISPR Therapeutics AG
CRSP
29
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Beigene Ltd
ONC
24
Intellia Therapeutics Inc
NTLA
24
1
2
3
...
109

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-02-06

The current price momentum score of Bicycle Therapeutics PLC is 6.34, ranking 264 out of 392 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 6.91 and the support level at 4.84, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
6.05
Change
0.29

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(3)
Neutral(1)
Buy(1)
Indicators
Value
Direction
MACD(12,26,9)
-0.264
Sell
RSI(14)
35.530
Neutral
STOCH(KDJ)(9,3,3)
13.656
Oversold
ATR(14)
0.391
High Vlolatility
CCI(14)
-135.675
Sell
Williams %R
81.159
Oversold
TRIX(12,20)
-0.438
Sell
StochRSI(14)
51.153
Buy
Moving Average
Sell(6)
Neutral(0)
Buy(0)
Indicators
Value
Direction
MA5
5.836
Sell
MA10
6.277
Sell
MA20
6.491
Sell
MA50
6.816
Sell
MA100
7.151
Sell
MA200
7.513
Sell

Institutional Confidence

Currency: USD Updated: 2026-02-06

The current institutional shareholding score of Bicycle Therapeutics PLC is 10.00, ranking 1 out of 392 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 114.58%, representing a quarter-over-quarter decrease of 9.44%. The largest institutional shareholder is PRFDX, holding a total of 1.38M shares, representing 2.77% of shares outstanding, with 13.79% decrease in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Baker Bros. Advisors LP
10.89M
--
Forbion Capital Partners
3.45M
--
Armistice Capital LLC
2.98M
+6.36%
Westfield Capital Management Company, L.P.
2.95M
+6.19%
Invus Public Equities Advisors, LLC
2.01M
--
Long Focus Capital Management LLC
1.42M
+7.70%
T. Rowe Price Associates, Inc.
Star Investors
1.38M
-5.69%
Candriam Luxembourg S.A.
1.35M
+0.05%
Acadian Asset Management LLC
1.31M
+88.20%
Candriam Belgium S.A.
1.17M
--
1
2

Risk Assessment

Currency: USD Updated: 2026-02-06

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Bicycle Therapeutics PLC is 4.00, ranking 111 out of 392 in the Biotechnology & Medical Research industry. The company's beta value is 1.66. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
4.00
Change
0
Beta vs S&P 500 index
1.66
VaR
+5.66%
240-Day Maximum Drawdown
+53.09%
240-Day Volatility
+69.09%

Return

Best Daily Return
60 days
+6.65%
120 days
+7.62%
5 years
+28.33%
Worst Daily Return
60 days
-7.55%
120 days
-10.19%
5 years
-38.69%
Sharpe Ratio
60 days
-1.29
120 days
-0.89
5 years
-0.24

Risk Assessment

Maximum Drawdown
240 days
+53.09%
3 years
+81.48%
5 years
+91.32%
Return-to-Drawdown Ratio
240 days
-0.94
3 years
-0.30
5 years
-0.18
Skewness
240 days
-0.06
3 years
+0.38
5 years
-0.14

Volatility

Realised Volatility
240 days
+69.09%
5 years
+76.69%
Standardised True Range
240 days
+8.65%
5 years
+26.52%
Downside Risk-Adjusted Return
120 days
-134.03%
240 days
-134.03%
Maximum Daily Upside Volatility
60 days
+37.01%
Maximum Daily Downside Volatility
60 days
+37.74%

Liquidity

Average Turnover Rate
60 days
+0.41%
120 days
+0.47%
5 years
--
Turnover Deviation
20 days
-48.96%
60 days
-44.11%
120 days
-35.11%

Peer Comparison

Biotechnology & Medical Research
Bicycle Therapeutics PLC
Bicycle Therapeutics PLC
BCYC
7.34 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.60 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.53 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ionis Pharmaceuticals Inc
Ionis Pharmaceuticals Inc
IONS
8.38 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.37 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.17 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
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