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Bicycle Therapeutics PLC

BCYC
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4.360USD
-0.090-2.02%
Close 05/18, 16:00ETQuotes delayed by 15 min
304.38MMarket Cap
LossP/E TTM

Bicycle Therapeutics PLC

4.360
-0.090-2.02%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Bicycle Therapeutics PLC

Currency: USD Updated: 2026-05-18

Key Insights

Bicycle Therapeutics PLC's fundamentals are relatively very healthy, with an industry-leading ESG disclosure.and its growth potential is high.Its valuation is considered fairly valued, ranking 111 out of 381 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 12.30.In the medium term, the stock price is expected to trend down.Despite a weak stock market performance over the past month, the company shows strong fundamentals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Bicycle Therapeutics PLC's Score

Industry at a Glance

Industry Ranking
111 / 381
Overall Ranking
235 / 4479
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Neutral

Bicycle Therapeutics PLC Highlights

StrengthsRisks
Bicycle Therapeutics plc is a United Kingdom-based clinical-stage biopharmaceutical company developing a class of medicines, referred to as Bicycle molecules, for diseases that are underserved by existing therapeutics. Bicycle molecules are fully synthetic short peptides constrained with small molecule scaffolds to form two loops that stabilize their structural geometry. The Company is evaluating zelenectide pevedotin, a Bicycle Toxin Conjugate (BTC) targeting Nectin-4, a well-validated tumor antigen; BT5528, a BTC targeting EphA2, a historically undruggable target, and BT7480, a Bicycle Tumor-Targeted Immune Cell Agonist (Bicycle TICA) targeting Nectin-4 and agonizing CD137, in Company-sponsored clinical trials. Additionally, the Company is developing Bicycle Radio Conjugates (BRC) for radiopharmaceutical use and, through various partnerships, is exploring the use of Bicycle technology to develop therapies for diseases beyond oncology.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 169.08% year-on-year.
Growing
The company is in a growing phase, with the latest annual income totaling USD 72.59M.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 72.59M.
Overvalued
The company’s latest PE is -1.38, at a high 3-year percentile range.
Institutional Selling
The latest institutional holdings are 33.87M shares, decreasing 40.59% quarter-over-quarter.
Held by Invesco
Star Investor Invesco holds 15.07K shares of this stock.
Lower Market Activity
The company has less investor interest, with a 20-day turnover ratio of 0.01.

Analyst Rating

Based on 12 analysts
Buy
Current Rating
12.300
Target Price
+176.40%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-05-18

The current financial score of Bicycle Therapeutics PLC is 6.84, ranking 175 out of 381 in the Biotechnology & Medical Research industry. Its financial status is robust, and its operating efficiency is low. Its latest quarterly revenue reached 887.00K, representing a year-over-year decrease of 91.11%, while its net profit experienced a year-over-year decrease of 0.12%.

Score

Industry at a Glance

Previous score
6.84
Change
0

Financials

9.30

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.90

Operational Efficiency

2.85

Growth Potential

7.05

Shareholder Returns

7.09

Bicycle Therapeutics PLC's Company Valuation

Currency: USD Updated: 2026-05-18

The current valuation score of Bicycle Therapeutics PLC is 7.66, ranking 89 out of 381 in the Biotechnology & Medical Research industry. Its current P/E ratio is -1.38, which is -4.63% below the recent high of -1.32 and -508.56% above the recent low of -8.41.

Score

Industry at a Glance

Previous score
7.66
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 111/381
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-05-18

The current earnings forecast score of Bicycle Therapeutics PLC is 7.85, ranking 267 out of 381 in the Biotechnology & Medical Research industry. The average price target is 16.00, with a high of 44.00 and a low of 6.00.

Score

Industry at a Glance

Previous score
7.85
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 12 analysts
Buy
Current Rating
12.300
Target Price
+176.40%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

554
Total
5
Median
6
Average
Company name
Ratings
Analysts
Bicycle Therapeutics PLC
BCYC
12
CRISPR Therapeutics AG
CRSP
29
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Beigene Ltd
ONC
26
Ionis Pharmaceuticals Inc
IONS
25
1
2
3
...
111

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-05-18

The current price momentum score of Bicycle Therapeutics PLC is 5.32, ranking 322 out of 381 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 5.01 and the support level at 4.01, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
5.43
Change
-0.11

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(3)
Neutral(1)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.090
Sell
RSI(14)
34.567
Neutral
STOCH(KDJ)(9,3,3)
8.701
Oversold
ATR(14)
0.229
High Vlolatility
CCI(14)
-177.359
Sell
Williams %R
95.531
Oversold
TRIX(12,20)
-0.216
Sell
StochRSI(14)
0.000
Oversold
Moving Average
Sell(6)
Neutral(0)
Buy(0)
Indicators
Value
Direction
MA5
4.588
Sell
MA10
4.739
Sell
MA20
4.782
Sell
MA50
4.843
Sell
MA100
5.514
Sell
MA200
6.437
Sell

Institutional Confidence

Currency: USD Updated: 2026-05-18

The current institutional shareholding score of Bicycle Therapeutics PLC is 5.00, ranking 134 out of 381 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 67.23%, representing a quarter-over-quarter decrease of 41.32%. The largest institutional shareholder is PRFDX, holding a total of 1.03M shares, representing 2.04% of shares outstanding, with 36.55% decrease in holdings.

Score

Industry at a Glance

Previous score
5.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Baker Bros. Advisors LP
10.92M
+0.35%
Forbion Capital Partners
3.47M
+0.47%
Armistice Capital LLC
3.24M
+8.66%
Acadian Asset Management LLC
1.67M
+27.13%
Long Focus Capital Management LLC
1.63M
+15.11%
Invus Public Equities Advisors, LLC
3.15M
+56.45%
GSK plc
1.53M
--
Principal Global Investors (Equity)
1.15M
-0.01%
T. Rowe Price Associates, Inc.
Star Investors
1.17M
-15.38%
Schroder Investment Management Ltd. (SIM)
584.77K
--
1
2

Risk Assessment

Currency: USD Updated: 2026-05-18

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Bicycle Therapeutics PLC is 4.00, ranking 104 out of 381 in the Biotechnology & Medical Research industry. The company's beta value is 1.55. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
4.00
Change
0
Beta vs S&P 500 index
1.55
VaR
+5.67%
240-Day Maximum Drawdown
+51.41%
240-Day Volatility
+61.87%

Return

Best Daily Return
60 days
+6.91%
120 days
+6.91%
5 years
+28.33%
Worst Daily Return
60 days
-7.30%
120 days
-7.55%
5 years
-38.69%
Sharpe Ratio
60 days
-1.68
120 days
-1.09
5 years
-0.27

Risk Assessment

Maximum Drawdown
240 days
+51.41%
3 years
+84.33%
5 years
+92.95%
Return-to-Drawdown Ratio
240 days
-0.92
3 years
-0.33
5 years
-0.18
Skewness
240 days
-0.03
3 years
+0.38
5 years
-0.13

Volatility

Realised Volatility
240 days
+61.87%
5 years
+76.34%
Standardised True Range
240 days
+8.81%
5 years
+32.58%
Downside Risk-Adjusted Return
120 days
-182.69%
240 days
-182.69%
Maximum Daily Upside Volatility
60 days
+41.68%
Maximum Daily Downside Volatility
60 days
+37.47%

Liquidity

Average Turnover Rate
60 days
+0.65%
120 days
+0.55%
5 years
--
Turnover Deviation
20 days
+1.13%
60 days
+21.72%
120 days
+2.42%

Peer Comparison

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