Avalo Therapeutics, Inc. is a clinical-stage biotechnology company focused on the treatment of immune dysregulation. The Company's lead asset is AVTX-009, an anti-IL-1β mAb, targeting inflammatory diseases. AVTX-009 is a humanized monoclonal antibody (IgG4) that binds to interleukin-1β (IL-1β) with high affinity and neutralizes its activity. IL-1β is a central driver in the inflammatory process. Overproduction or dysregulation of IL-1β is implicated in many autoimmune and inflammatory diseases. IL-1β is a major, validated target for therapeutic intervention. There is evidence that inhibition of IL-1β could be effective in hidradenitis suppurativa and a variety of inflammatory diseases in dermatology, gastroenterology, and rheumatology. AVTX-009 is in the Phase II LOTUS trial for hidradenitis suppurativa (HS).
Growing
The company is in a growing phase, with the latest annual income totaling USD 59.00K.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 59.00K.
Undervalued
The company’s latest PE is -3.39, at a low 3-year percentile range.
Institutional Buying
The latest institutional holdings are 24.87M shares, increasing 21.84% quarter-over-quarter.
Held by Steven Cohen
Star Investor Steven Cohen holds 866.37K shares of this stock.
Higher Market Activity
The company has more investor interest, with a 20-day turnover ratio of 3.71.