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aTyr Pharma Inc

ATYR
0.827USD
-0.054-6.14%
Close 11/04, 16:00ETQuotes delayed by 15 min
76.77MMarket Cap
LossP/E TTM

aTyr Pharma Inc

0.827
-0.054-6.14%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of aTyr Pharma Inc

Currency: USD Updated: 2025-11-03

Key Insights

The company's fundamentals are relatively weak. Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Hold. Despite a good stock market performance and strong technicals, the fundamentals don't support the current trend. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

aTyr Pharma Inc's Score

Industry at a Glance

Industry Ranking
170 / 407
Overall Ranking
307 / 4617
Industry
Biotechnology & Medical Research

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 11 analysts
Hold
Current Rating
10.111
Target Price
+1067.56%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

aTyr Pharma Inc Highlights

StrengthsRisks
aTyr Pharma, Inc. is a clinical-stage biotechnology company. The Company is leveraging intelligence to translate tRNA synthetase biology into new therapies for fibrosis and inflammation. Its lead therapeutic candidate is efzofitimod, a biologic immunomodulator in clinical development for the treatment of interstitial lung disease (ILD), a group of immune-mediated disorders that can cause inflammation and fibrosis, or scarring, of the lungs. Efzofitimod is a tRNA synthetase derived therapy that selectively modulates activated myeloid cells through neuropilin-2 (NRP2) to resolve aberrant inflammation without immune suppression and prevent the progression of fibrosis. ATYR0101 is a fusion protein derived from a domain of aspartyl-tRNA synthetase (DARS). ATYR0101 binds directly to latent-transforming growth factor beta-binding protein 1 (LTBP1), which regulates transforming growth factor beta (TGFb). Its ATYR0750 is a fusion protein derived from a domain of alanyl-tRNA synthetase (AARS).
Growing
The company is in a growing phase, with the latest annual income totaling USD 235.00K.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 235.00K.
Overvalued
The company’s latest PE is -1.11, at a high 3-year percentile range.
Institutional Selling
The latest institutional holdings are 63.66M shares, decreasing 5.59% quarter-over-quarter.
Held by James Simons
Star Investor James Simons holds 518.36K shares of this stock.
Lower Market Activity
The company has less investor interest, with a 20-day turnover ratio of 1.87.

Financial Health

Currency: USD Updated: 2025-11-03

The company's current financial score is 5.15, which is lower than the Biotechnology & Medical Research industry's average of 6.92. Its financial status is weak, and its operating efficiency is low.

Score

Industry at a Glance

Previous score
5.15
Change
0

Financials

2.04

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
No Data

Quality of Earnings

7.64

Operational Efficiency

2.69

Growth Potential

6.36

Shareholder Returns

7.03

aTyr Pharma Inc's Company Valuation

Currency: USD Updated: 2025-11-03

The company’s current valuation score is 7.36, which is higher than the Biotechnology & Medical Research industry's average of 7.05. Its current P/E ratio is -1.11, which is -21.60% below the recent high of -0.87 and -650.57% above the recent low of -8.34.

Score

Industry at a Glance

Previous score
7.36
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 170/407
No Data

Earnings Forecast

Currency: USD Updated: 2025-11-03

The company’s current earnings forecast score is 6.91, which is lower than the Biotechnology & Medical Research industry's average of 8.01. The average price target for aTyr Pharma Inc is 3.50, with a high of 35.00 and a low of 1.00.

Score

Industry at a Glance

Previous score
6.91
Change
0

Support & Resistance

No Data

Analyst Rating

Based on 11 analysts
Hold
Current Rating
10.111
Target Price
+1048.08%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

521
Total
6
Median
6
Average
Company name
Ratings
Analysts
aTyr Pharma Inc
ATYR
11
CRISPR Therapeutics AG
CRSP
30
Ionis Pharmaceuticals Inc
IONS
25
argenx SE
ARGX
25
Intellia Therapeutics Inc
NTLA
25
IQVIA Holdings Inc
IQV
25
1
2
3
...
104

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-11-03

The company’s current price momentum score is 6.59, which is higher than the Biotechnology & Medical Research industry's average of 6.58. Sideways: Currently, the stock price is trading between the resistance level at 1.07 and the support level at 0.75, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
6.52
Change
0.07

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(3)
Neutral(1)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
0.161
Neutral
RSI(14)
29.161
Sell
STOCH(KDJ)(9,3,3)
9.964
Oversold
ATR(14)
0.066
Low Volatility
CCI(14)
-166.080
Sell
Williams %R
96.779
Oversold
TRIX(12,20)
-2.320
Sell
StochRSI(14)
0.000
Oversold
Moving Average
Sell(6)
Neutral(0)
Buy(0)
Indicators
Value
Direction
MA5
0.886
Sell
MA10
0.927
Sell
MA20
0.969
Sell
MA50
2.108
Sell
MA100
3.702
Sell
MA200
3.677
Sell

Institutional Confidence

Currency: USD Updated: 2025-11-03

The company’s current institutional recognition score is 5.00, which is lower than the Biotechnology & Medical Research industry's average of 5.15. The latest institutional shareholding proportion is 64.97%, representing a quarter-over-quarter decrease of 13.07%. The largest institutional shareholder is The Vanguard, holding a total of 4.66M shares, representing 4.75% of shares outstanding, with 10.62% increase in holdings.

Score

Industry at a Glance

Previous score
5.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
Fidelity Management & Research Company LLC
13.35M
+3.55%
Federated Hermes Global Investment Management Corp.
14.67M
--
BlackRock Institutional Trust Company, N.A.
5.34M
+253.28%
The Vanguard Group, Inc.
Star Investors
4.66M
+16.18%
Octagon Capital Advisors LP
3.82M
+7.55%
Tikvah Management LLC
2.46M
--
Geode Capital Management, L.L.C.
2.10M
+126.13%
UBS Financial Services, Inc.
1.75M
+8.60%
Woodline Partners LP
1.68M
--
Millennium Management LLC
1.60M
+0.07%
1
2

Risk Assessment

Currency: USD Updated: 2025-11-03

The company’s current risk assessment score is 1.52, which is lower than the Biotechnology & Medical Research industry's average of 3.47. The company's beta value is 0.81. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets.

Score

Industry at a Glance

Previous score
1.52
Change
0
Beta vs S&P 500 index
0.57
VaR
+6.20%
240-Day Maximum Drawdown
+89.56%
240-Day Volatility
+187.12%

Return

Best Daily Return
60 days
+19.57%
120 days
+26.15%
5 years
+66.97%
Worst Daily Return
60 days
-83.17%
120 days
-83.17%
5 years
-83.17%
Sharpe Ratio
60 days
-1.61
120 days
-0.20
5 years
+0.19

Risk Assessment

Maximum Drawdown
240 days
+89.56%
3 years
+89.56%
5 years
+94.47%
Return-to-Drawdown Ratio
240 days
-0.78
3 years
-0.22
5 years
-0.17
Skewness
240 days
-4.96
3 years
-4.26
5 years
-0.38

Volatility

Realised Volatility
240 days
+187.12%
5 years
+109.83%
Standardised True Range
240 days
+37.59%
5 years
+28.57%
Downside Risk-Adjusted Return
120 days
-17.07%
240 days
-17.07%
Maximum Daily Upside Volatility
60 days
+186.54%
Maximum Daily Downside Volatility
60 days
+173.34%

Liquidity

Average Turnover Rate
60 days
+5.02%
120 days
+3.39%
5 years
--
Turnover Deviation
20 days
+186.95%
60 days
+234.30%
120 days
+125.74%

Peer Comparison

Biotechnology & Medical Research
aTyr Pharma Inc
aTyr Pharma Inc
ATYR
5.74 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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Zymeworks Inc
ZYME
8.55 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
CytomX Therapeutics Inc
CytomX Therapeutics Inc
CTMX
8.51 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Insmed Inc
Insmed Inc
INSM
8.49 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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NAMS
8.49 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
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Amicus Therapeutics Inc
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8.47 /10
Score
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