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Arrowhead Pharmaceuticals Inc

ARWR
68.160USD
+1.690+2.54%
Close 12/19, 16:00ETQuotes delayed by 15 min
9.25BMarket Cap
LossP/E TTM

Arrowhead Pharmaceuticals Inc

68.160
+1.690+2.54%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Arrowhead Pharmaceuticals Inc

Currency: USD Updated: 2025-12-19

Key Insights

Arrowhead Pharmaceuticals Inc's fundamentals are relatively healthy, and its growth potential is high.Its valuation is considered fairly valued, ranking 17/404 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 59.54.In the medium term, the stock price is expected to trend up.The company has been performing strongly in the stock market over the past month, which is supported by its strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Arrowhead Pharmaceuticals Inc's Score

Industry at a Glance

Industry Ranking
17 / 404
Overall Ranking
88 / 4582
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Analyst Rating

Based on 14 analysts
Buy
Current Rating
59.538
Target Price
-13.21%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Arrowhead Pharmaceuticals Inc Highlights

StrengthsRisks
Arrowhead Pharmaceuticals, Inc. develops medicines that treat intractable diseases by silencing the genes that cause them. The Company's therapies, using a broad portfolio of ribonucleic acid (RNA) chemistries and modes of delivery, trigger the RNA interference (RNAi) mechanism to induce rapid, deep and durable knockdown of target genes. The Company's Targeted RNAi Molecule (TRiMTM) platform utilizes ligand-mediated delivery and is designed to enable tissue-specific targeting while being structurally simple. It is focused on various therapeutic areas, such as cardiometabolic, pulmonary, liver, muscle and central nervous system. It has around 16 clinical-stage investigational medicines (wholly owned and partnered), which range in development stage from Phase I to Phase III. The Company's pipeline products include Plozasiran, Zodasiran, Olpasiran, ARO-RAGE, ARO-MMP7, GSK-4532990, Fazirsiran, GSK5637608, ARO-CFB, ARO-INHBE, ARO-C3, ARO-PNPLA3, ARO-DUX4, ARO-DM1 and ARO-ATXN2.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 244.55% year-on-year.
Undervalued
The company’s latest PE is -5591.47, at a low 3-year percentile range.
Institutional Buying
The latest institutional holdings are 114.80M shares, increasing 0.01% quarter-over-quarter.
Held by CI Select Canadian Equity Fund
Star Investor CI Select Canadian Equity Fund holds 477.00 shares of this stock.
Higher Market Activity
The company has more investor interest, with a 20-day turnover ratio of 0.43.

Financial Health

Currency: USD Updated: 2025-12-19

The current financial score of Arrowhead Pharmaceuticals Inc is 8.71, ranking 38/404 in the Biotechnology & Medical Research industry. Its financial status is stable, and its operating efficiency is high.

Score

Industry at a Glance

Previous score
8.71
Change
0

Financials

7.07

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

8.69

Operational Efficiency

10.00

Growth Potential

10.00

Shareholder Returns

7.77

Arrowhead Pharmaceuticals Inc's Company Valuation

Currency: USD Updated: 2025-12-19

The current valuation score of Arrowhead Pharmaceuticals Inc is 7.14, ranking 171/404 in the Biotechnology & Medical Research industry. Its current P/E ratio is -5591.47, which is -99.95% below the recent high of -2.68 and -3.90% above the recent low of -5809.68.

Score

Industry at a Glance

Previous score
7.14
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 17/404
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2025-12-19

The current earnings forecast score of Arrowhead Pharmaceuticals Inc is 7.71, ranking 270/404 in the Biotechnology & Medical Research industry. The average price target for Arrowhead Pharmaceuticals Inc is 61.00, with a high of 85.00 and a low of 17.00.

Score

Industry at a Glance

Previous score
7.71
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 14 analysts
Buy
Current Rating
59.538
Target Price
-13.21%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

534
Total
6
Median
6
Average
Company name
Ratings
Analysts
Arrowhead Pharmaceuticals Inc
ARWR
14
CRISPR Therapeutics AG
CRSP
30
argenx SE
ARGX
25
Intellia Therapeutics Inc
NTLA
25
IQVIA Holdings Inc
IQV
25
Ionis Pharmaceuticals Inc
IONS
24
1
2
3
...
107

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-12-19

The current price momentum score of Arrowhead Pharmaceuticals Inc is 9.54, ranking 12/404 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 81.20 and the support level at 46.27, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
9.50
Change
0.04

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(1)
Neutral(4)
Buy(2)
Indicators
Value
Direction
MACD(12,26,9)
-0.815
Neutral
RSI(14)
67.690
Neutral
STOCH(KDJ)(9,3,3)
59.839
Neutral
ATR(14)
4.814
High Vlolatility
CCI(14)
37.134
Neutral
Williams %R
25.286
Buy
TRIX(12,20)
2.110
Sell
StochRSI(14)
49.851
Buy
Moving Average
Sell(0)
Neutral(0)
Buy(6)
Indicators
Value
Direction
MA5
66.508
Buy
MA10
67.975
Buy
MA20
61.352
Buy
MA50
48.031
Buy
MA100
37.055
Buy
MA200
26.024
Buy

Institutional Confidence

Currency: USD Updated: 2025-12-19

The current institutional shareholding score of Arrowhead Pharmaceuticals Inc is 7.00, ranking 85/404 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 88.39%, representing a quarter-over-quarter decrease of 0.40%. The largest institutional shareholder is The Vanguard, holding a total of 16.01M shares, representing 11.79% of shares outstanding, with 23.55% increase in holdings.

Score

Industry at a Glance

Previous score
7.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
BlackRock Institutional Trust Company, N.A.
17.60M
-3.23%
The Vanguard Group, Inc.
Star Investors
15.50M
+17.63%
Avoro Capital Advisors LLC
10.60M
-4.60%
State Street Investment Management (US)
6.37M
-8.98%
Fidelity Management & Research Company LLC
5.17M
+55.96%
Slate Path Capital LP
5.23M
--
Anzalone (Christopher Richard)
3.92M
-3.47%
Geode Capital Management, L.L.C.
2.98M
+0.96%
Invus Public Equities Advisors, LLC
2.67M
--
1
2

Risk Assessment

Currency: USD Updated: 2025-12-19

The current risk assessment score of Arrowhead Pharmaceuticals Inc is 6.04, ranking 38/404 in the Biotechnology & Medical Research industry. The company's beta value is 1.17. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets.

Score

Industry at a Glance

Previous score
6.04
Change
0
Beta vs S&P 500 index
1.17
VaR
+5.87%
240-Day Maximum Drawdown
+53.60%
240-Day Volatility
+71.41%

Return

Best Daily Return
60 days
+23.34%
120 days
+23.34%
5 years
+24.23%
Worst Daily Return
60 days
-8.68%
120 days
-12.23%
5 years
-26.85%
Sharpe Ratio
60 days
+4.20
120 days
+4.34
5 years
+0.31

Risk Assessment

Maximum Drawdown
240 days
+53.60%
3 years
+75.86%
5 years
+88.94%
Return-to-Drawdown Ratio
240 days
+4.66
3 years
+0.45
5 years
-0.01
Skewness
240 days
+0.70
3 years
+0.39
5 years
+0.01

Volatility

Realised Volatility
240 days
+71.41%
5 years
+62.48%
Standardised True Range
240 days
+2.32%
5 years
+2.91%
Downside Risk-Adjusted Return
120 days
+765.90%
240 days
+765.90%
Maximum Daily Upside Volatility
60 days
+72.30%
Maximum Daily Downside Volatility
60 days
+45.88%

Liquidity

Average Turnover Rate
60 days
+1.46%
120 days
+1.43%
5 years
--
Turnover Deviation
20 days
+42.56%
60 days
+19.10%
120 days
+16.98%

Peer Comparison

Biotechnology & Medical Research
Arrowhead Pharmaceuticals Inc
Arrowhead Pharmaceuticals Inc
ARWR
8.00 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Amicus Therapeutics Inc
Amicus Therapeutics Inc
FOLD
8.80 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.42 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Charles River Laboratories International Inc
Charles River Laboratories International Inc
CRL
8.41 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Madrigal Pharmaceuticals Inc
Madrigal Pharmaceuticals Inc
MDGL
8.35 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.30 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more

FAQs

How does TradingKey generate the Stock Score of Arrowhead Pharmaceuticals Inc?

The TradingKey Stock Score provides a comprehensive assessment of Arrowhead Pharmaceuticals Inc based on 34 indicators derived from over 100 underlying data points.
These indicators are categorised into six key dimensions: financial health, company profile, earnings forecasts, price momentum, institutional confidence, and risk assessment, collectively providing investors with a thorough analysis of Arrowhead Pharmaceuticals Inc’s performance and outlook.

How do we generate the financial health score of Arrowhead Pharmaceuticals Inc?

To generate the financial health score of Arrowhead Pharmaceuticals Inc, we analyse various key financial indicators across several core dimensions, including financial fundamentals, earnings quality, operational efficiency, growth potential, and shareholder returns.
By integrating these comprehensive data, the financial health score not only reflects Arrowhead Pharmaceuticals Inc's overall stability, operational efficiency, and growth potential but also captures the investment returns delivered to shareholders. This score aims to support rational decision-making for investors and other stakeholders. A higher score indicates a better financial health of Arrowhead Pharmaceuticals Inc.

How do we generate the company valuation score of Arrowhead Pharmaceuticals Inc?

To generate the company valuation score of Arrowhead Pharmaceuticals Inc, we use several key financial ratios, including P/E, P/B, P/S, and P/CF. These metrics compare Arrowhead Pharmaceuticals Inc’s market value to its earnings, assets, sales, and cash flow, serving as core indicators for assessing company value.
By analysing these ratios in an all-round manner, the valuation score reflects not only the market’s current perception of Arrowhead Pharmaceuticals Inc’s value but also its future profitability and growth potential, thereby supporting more informed investment decisions. A higher score indicates a fairer valuation of Arrowhead Pharmaceuticals Inc.

How do we generate the earnings forecast score of Arrowhead Pharmaceuticals Inc?

To calculate the earnings forecast score of Arrowhead Pharmaceuticals Inc, we consider various key indicators such as analyst ratings, financial forecasts, support and resistance levels, and peer comparisons:
Current ratings and price targets directly reflect analysts’ expectations, while the upside space indicates their views on the stock’s growth potential.
Financial metrics like earnings per share (EPS), revenue, net income, and earnings before interest and taxes (EBIT) are core measures for assessing profitability.
By analysing the high, median, and low ranges of the target price, we can identify price trends and determine key support and resistance levels.
Comparing these indicators against peers provides context for the stock’s performance and helps anchor more realistic expectations.
These factors together form a comprehensive earnings forecast score that accurately reflects the stock’s expected financial performance and growth potential. A higher score suggests that analysts have a more optimistic outlook on Arrowhead Pharmaceuticals Inc’s future.

How do we generate the price momentum score of Arrowhead Pharmaceuticals Inc?

When generating the price momentum score for Arrowhead Pharmaceuticals Inc, we examine momentum indicators including support and resistance levels as well as volume metrics.
Support levels represent price points where buying interest is strong enough to prevent further declines, while resistance levels indicate prices where selling pressure may hinder upward movement. By analysing typical price volume alongside total volume, we assess overall market activity and liquidity. These indicators help identify price trends and potential shifts, enabling more accurate predictions of future earnings.
This comprehensive approach can reflect market sentiment and enable rational forecasts of Arrowhead Pharmaceuticals Inc’s prices. A higher score indicates a more stable short-term price trend for Arrowhead Pharmaceuticals Inc.

How do we generate the institutional confidence score of Arrowhead Pharmaceuticals Inc?

To generate the institutional confidence score of Arrowhead Pharmaceuticals Inc, we analyse both the proportion of shares held by institutions and the number of shares they own. A higher institutional ownership percentage indicates strong confidence of professional investors, which is generally a positive signal about Arrowhead Pharmaceuticals Inc’s potential. By examining the number of shares held, we gain deeper insight into institutions’ commitment and attitude toward the stock, as institutional investors typically conduct thorough analysis before making investment decisions. Understanding institutional confidence helps us refine earnings forecasts and provides a more reliable perspective on the company’s future performance and market stability. A higher score indicates greater institutional endorsement of Arrowhead Pharmaceuticals Inc.

How do we generate the risk management score of Arrowhead Pharmaceuticals Inc?

To assess the risk management score of Arrowhead Pharmaceuticals Inc, we examine multiple key indicators related to returns, risk, volatility, and liquidity.
The highest and lowest daily returns reflect the potential size of gains and losses, while the Sharpe ratio measures risk-adjusted return performance. On the risk side, we analyse maximum drawdown and the return-to-drawdown ratio to identify extreme loss scenarios. Skewness helps assess the distribution of returns and whether performance may be biased. Volatility indicators—such as realised volatility and standardised true range—reveal price fluctuations. Downside risk-adjusted returns provide insight into potential losses and gains. Lastly, liquidity metrics like average turnover rate and turnover deviation indicate how actively the stock is traded.
These indicators together provide a multi-dimensional understanding of Arrowhead Pharmaceuticals Inc’s risk-return profile, serving as core factors of the risk management score. A higher score indicates lower risk on the side of Arrowhead Pharmaceuticals Inc.
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