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Aprea Therapeutics Inc

APRE
0.690USD
+0.066+10.51%
Close 02/06, 16:00ETQuotes delayed by 15 min
4.13MMarket Cap
LossP/E TTM

Aprea Therapeutics Inc

0.690
+0.066+10.51%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Aprea Therapeutics Inc

Currency: USD Updated: 2026-02-06

Key Insights

Aprea Therapeutics Inc's fundamentals are relatively very healthy, with an industry-leading ESG disclosure.and its growth potential is significant.Its valuation is considered fairly valued, ranking 108 out of 392 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 6.67.In the medium term, the stock price is expected to trend down.Despite a very weak market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Aprea Therapeutics Inc's Score

Industry at a Glance

Industry Ranking
108 / 392
Overall Ranking
238 / 4521
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Neutral

Aprea Therapeutics Inc Highlights

StrengthsRisks
Aprea Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on precision oncology through synthetic lethality. The Company’s pipeline includes two clinical-stage synthetic lethality programs. Its lead programs are APR-1051, an oral, small-molecule inhibitor of WEE1 kinase, and ATRN-119, a small-molecule ATR inhibitor, both in clinical development for solid tumor indications. Its ATRN-119 is an oral small molecule inhibitor of ataxia telangiectasia and Rad3-related (ATR). The ATR kinase is a master regulator of Deoxyribonucleic Acid (DNA) damage response, with roles in cell cycle control and DNA repair following replication stress. It is evaluating potential combination opportunities within its pipeline, including research on the combination of ATRN-119 and APR-1051 that is supported by a Phase II SBIR grant from the National Cancer Institute. It also has an early-stage program, in the lead optimization stage, for an undisclosed DNA-damage response (DDR) target.
Growing
The company is in a growing phase, with the latest annual income totaling USD 1.50M.
Fairly Valued
The company’s latest PE is -0.32, at a medium 3-year percentile range.
Held by The Vanguard
Star Investor The Vanguard holds 58.09K shares of this stock.

Analyst Rating

Based on 3 analysts
Buy
Current Rating
6.667
Target Price
+967.69%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-02-06

The current financial score of Aprea Therapeutics Inc is 6.49, ranking 249 out of 392 in the Biotechnology & Medical Research industry. Its financial status is robust, and its operating efficiency is low. Its latest quarterly revenue reached 1.85K, representing a year-over-year decrease of 99.48%, while its net profit experienced a year-over-year decrease of 21.44%.

Score

Industry at a Glance

Previous score
6.49
Change
0

Financials

10.00

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.73

Operational Efficiency

2.83

Growth Potential

4.84

Shareholder Returns

7.07

Aprea Therapeutics Inc's Company Valuation

Currency: USD Updated: 2026-02-06

The current valuation score of Aprea Therapeutics Inc is 8.87, ranking 8 out of 392 in the Biotechnology & Medical Research industry. Its current P/E ratio is -0.32, which is -100.00% below the recent high of 0.00 and -559.34% above the recent low of -2.14.

Score

Industry at a Glance

Previous score
8.87
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 108/392
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-02-06

The current earnings forecast score of Aprea Therapeutics Inc is 8.67, ranking 70 out of 392 in the Biotechnology & Medical Research industry. The average price target is 10.50, with a high of 11.00 and a low of 10.00.

Score

Industry at a Glance

Previous score
8.67
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 3 analysts
Buy
Current Rating
6.667
Target Price
+967.69%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

542
Total
6
Median
6
Average
Company name
Ratings
Analysts
Aprea Therapeutics Inc
APRE
3
CRISPR Therapeutics AG
CRSP
29
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Beigene Ltd
ONC
24
Intellia Therapeutics Inc
NTLA
24
1
2
3
...
109

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-02-06

The current price momentum score of Aprea Therapeutics Inc is 6.62, ranking 210 out of 392 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 1.27 and the support level at 0.33, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
6.50
Change
0.12

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(2)
Neutral(2)
Buy(1)
Indicators
Value
Direction
MACD(12,26,9)
-0.019
Sell
RSI(14)
39.884
Neutral
STOCH(KDJ)(9,3,3)
13.280
Oversold
ATR(14)
0.151
High Vlolatility
CCI(14)
-93.049
Neutral
Williams %R
84.926
Oversold
TRIX(12,20)
-1.165
Sell
StochRSI(14)
90.605
Buy
Moving Average
Sell(5)
Neutral(0)
Buy(1)
Indicators
Value
Direction
MA5
0.682
Buy
MA10
0.721
Sell
MA20
0.802
Sell
MA50
0.907
Sell
MA100
1.152
Sell
MA200
1.428
Sell

Institutional Confidence

Currency: USD Updated: 2026-02-06

The current institutional shareholding score of Aprea Therapeutics Inc is 3.00, ranking 197 out of 392 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 35.08%, representing a quarter-over-quarter decrease of 5.25%. The largest institutional shareholder is The Vanguard, holding a total of 58.09K shares, representing 0.83% of shares outstanding, with 73.66% decrease in holdings.

Score

Industry at a Glance

Previous score
3.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Lytton (Laurence W)
681.84K
--
Gilad (Oren)
333.19K
+1.23%
AIGH Capital Management, LLC.
382.06K
--
Sphera Funds Management Ltd.
270.00K
--
Duey (Marc)
255.71K
+9.16%
Nantahala Capital Management, LLC
205.76K
--
Worth Venture Partners, LLC
157.24K
--
Dafna Capital Management, LLC
137.17K
--
Sio Capital Management, LLC
112.22K
-59.83%
Morgan Stanley & Co. LLC
65.73K
+30.86%
1
2

Risk Assessment

Currency: USD Updated: 2026-02-06

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Aprea Therapeutics Inc is 2.31, ranking 236 out of 392 in the Biotechnology & Medical Research industry. The company's beta value is 1.49. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets. Aprea Therapeutics Inc’s latest ESG disclosure leads the Biotechnology & Medical Research industry, indicating outstanding, compliant performance across environmental management, social responsibility, and governance, which may help mitigate overall risk.

Score

Industry at a Glance

Previous score
2.31
Change
0
Beta vs S&P 500 index
1.49
VaR
+7.83%
240-Day Maximum Drawdown
+77.65%
240-Day Volatility
+118.51%

Return

Best Daily Return
60 days
+34.92%
120 days
+34.92%
5 years
+34.92%
Worst Daily Return
60 days
-22.78%
120 days
-22.78%
5 years
-29.68%
Sharpe Ratio
60 days
-2.04
120 days
-2.14
5 years
-0.84

Risk Assessment

Maximum Drawdown
240 days
+77.65%
3 years
+93.03%
5 years
+100.00%
Return-to-Drawdown Ratio
240 days
-0.94
3 years
-0.30
5 years
-0.20
Skewness
240 days
+1.52
3 years
+1.26
5 years
+0.82

Volatility

Realised Volatility
240 days
+118.51%
5 years
--
Standardised True Range
240 days
+18.80%
5 years
+231.56%
Downside Risk-Adjusted Return
120 days
-298.98%
240 days
-298.98%
Maximum Daily Upside Volatility
60 days
+307.75%
Maximum Daily Downside Volatility
60 days
+82.39%

Liquidity

Average Turnover Rate
60 days
+0.93%
120 days
+0.73%
5 years
--
Turnover Deviation
20 days
+74.02%
60 days
+70.34%
120 days
+33.05%

Peer Comparison

Biotechnology & Medical Research
Aprea Therapeutics Inc
Aprea Therapeutics Inc
APRE
6.54 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.60 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ascendis Pharma A/S
Ascendis Pharma A/S
ASND
8.53 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Ionis Pharmaceuticals Inc
Ionis Pharmaceuticals Inc
IONS
8.38 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.37 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.17 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more
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