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Aprea Therapeutics Inc

APRE

1.440USD

-0.060-4.00%
Close 09/19, 16:00ETQuotes delayed by 15 min
8.28MMarket Cap
LossP/E TTM

Aprea Therapeutics Inc

1.440

-0.060-4.00%

TradingKey Stock Score

Overall Financial Health

Valuation Dimensions

Earnings Forecast

Price Momentum

Institutional Confidence

Risk Assessment

Peer Comparison

TradingKey Stock Score

Overall Financial Health

Valuation Dimensions

Earnings Forecast

Price Momentum

Institutional Confidence

Risk Assessment

Peer Comparison

TradingKey Stock Score

Currency: USD Updated: 2025-09-19

Key Insights

The company's fundamentals are relatively very healthy. Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Strong Buy. Despite a good stock market performance and outperforming fundamentals, the technicals don't support the current trend. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Industry Ranking
162 / 506
Overall Ranking
273 / 4720
Industry
Biotechnology & Medical Research

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 2 analysts
Strong Buy
Current Rating
10.500
Target Price
+600.00%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Company Highlights

StrengthsRisks
Aprea Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on precision oncology through synthetic lethality. The Company's advanced synthetic lethality product candidate is ATRN-119, a clinical-stage small molecule inhibitor of ataxia telangiectasia and Rad3-related (ATR) a kinase that plays a critical role in DNA damage response (DDR). ATR and Checkpoint Kinase 1 are critical DDR kinases that prevent the collapse of replication forks into DNA double-strand breaks. It has completed all IND enabling studies for its oral, small molecule WEE1 inhibitor, APR-1051, and received United States Food and Drug Administration (FDA) clearance of its IND. It has an early-stage program that is in the lead optimization stage, for an undisclosed DDR target. The Company is evaluating potential combination opportunities within its pipeline, including research on the combination of ATRN-119 and APR-1051 that is supported by a Phase II SBIR grant from the National Cancer Institute.
Growing
The company is in a growing phase, with the latest annual income totaling USD 1.50M.
Fairly Valued
The company’s latest PE is -0.63, at a medium 3-year percentile range.
Institutional Selling
The latest institutional holdings are 2.92M shares, decreasing 1.43% quarter-over-quarter.
Held by The Vanguard
Star Investor The Vanguard holds 173.84K shares of this stock.

Financial Health

Currency: USD Updated: 2025-09-19

The company's current financial score is 6.38, which is lower than the Biotechnology & Medical Research industry's average of 6.93. Its financial status is robust, and its operating efficiency is low. Its latest quarterly revenue reached 118.11K, representing a year-over-year decrease of 78.97%, while its net profit experienced a year-over-year decrease of 6.66%.

Score

Industry at a Glance

Previous score
6.38
Change
0

Financials

9.42

Key Metrics

Cash and cash equivalents

Total assets

Total liabilities

Free cash flow

No Data

Quality of Earnings

7.68

Operational Efficiency

2.57

Growth Potential

5.14

Shareholder Returns

7.11

Company Valuation

Currency: USD Updated: 2025-09-19

The company’s current valuation score is 2.80, which is lower than the Biotechnology & Medical Research industry's average of 3.06. Its current P/E ratio is -0.65, which is -99.06% below the recent high of -0.01 and -78.79% above the recent low of -1.17.

Score

Industry at a Glance

Previous score
2.80
Change
0

Valuation Dimensions

P/E

P/B

P/S

P/CF

Industry Ranking 162/506
No Data

Earnings Forecast

Currency: USD Updated: 2025-09-19

The company’s current earnings forecast score is 9.00, which is higher than the Biotechnology & Medical Research industry's average of 8.03. The average price target for Aprea Therapeutics Inc is 10.50, with a high of 11.00 and a low of 10.00.

Score

Industry at a Glance

Previous score
9.00
Change
0

Support & Resistance

No Data

Analyst Rating

Based on 2 analysts
Strong Buy
Current Rating
10.500
Target Price
+629.17%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

554
Total
5
Median
6
Average
Company name
Ratings
Analysts
Aprea Therapeutics Inc
APRE
2
CRISPR Therapeutics AG
CRSP
30
Intellia Therapeutics Inc
NTLA
26
Exact Sciences Corp
EXAS
26
Ionis Pharmaceuticals Inc
IONS
26
IQVIA Holdings Inc
IQV
25
1
2
3
...
111

Financial Forecasting

EPS

Revenue

Net Profit

EBIT

No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-09-19

The company’s current price momentum score is 4.01, which is lower than the Biotechnology & Medical Research industry's average of 6.58. Sideways: Currently, the stock price is trading between the resistance level at 1.65 and the support level at 1.39, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
4.01
Change
-0.04

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(4)
Neutral(1)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.009
Sell
RSI(14)
36.804
Neutral
STOCH(KDJ)(9,3,3)
16.057
Oversold
ATR(14)
0.081
High Vlolatility
CCI(14)
-137.172
Sell
Williams %R
91.837
Oversold
TRIX(12,20)
-0.430
Sell
StochRSI(14)
10.751
Sell
Moving Average
Sell(6)
Neutral(0)
Buy(0)
Indicators
Value
Direction
MA5
1.481
Sell
MA10
1.522
Sell
MA20
1.547
Sell
MA50
1.655
Sell
MA100
1.698
Sell
MA200
2.288
Sell

Institutional Confidence

Currency: USD Updated: 2025-09-19

The company’s current institutional recognition score is 5.00, which is lower than the Biotechnology & Medical Research industry's average of 5.96. The latest institutional shareholding proportion is 52.85%, representing a quarter-over-quarter increase of 3.52%. The largest institutional shareholder is The Vanguard, holding a total of 173.84K shares, representing 2.98% of shares outstanding, with 5.91% decrease in holdings.

Score

Industry at a Glance

Previous score
5.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
AIGH Capital Management, LLC.
382.06K
--
Gilad (Oren Ph.D.)
333.19K
+1.23%
Sio Capital Management, LLC
276.60K
--
Sphera Funds Management Ltd.
583.00K
+115.93%
Duey (Marc)
234.25K
+0.45%
Nantahala Capital Management, LLC
205.76K
--
The Vanguard Group, Inc.
Star Investors
173.84K
--
Worth Venture Partners, LLC
157.24K
--
Dafna Capital Management, LLC
137.17K
--
Morgan Stanley & Co. LLC
32.73K
-10.89%
1
2

Risk Assessment

Currency: USD Updated: 2025-09-19

The company’s current risk assessment score is 3.11, which is lower than the Biotechnology & Medical Research industry's average of 3.33. The company's beta value is 1.31. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets.

Score

Industry at a Glance

Previous score
3.11
Change
0
Beta vs S&P 500 index
1.31
VaR
+7.77%
240-Day Maximum Drawdown
+67.64%
240-Day Volatility
+120.32%
Return
Best Daily Return
60 days
+20.23%
120 days
+20.23%
5 years
+30.55%
Worst Daily Return
60 days
-8.38%
120 days
-8.57%
5 years
-78.08%
Sharpe Ratio
60 days
-0.44
120 days
-0.91
5 years
-0.81
Risk Assessment
Maximum Drawdown
240 days
+67.64%
3 years
+100.00%
5 years
+100.00%
Return-to-Drawdown Ratio
240 days
-0.67
3 years
-0.30
5 years
-0.20
Skewness
240 days
+1.31
3 years
+1.07
5 years
-1.59
Volatility
Realised Volatility
240 days
+120.32%
5 years
--
Standardised True Range
240 days
+16.72%
5 years
+204.66%
Downside Risk-Adjusted Return
120 days
-196.51%
240 days
-196.51%
Maximum Daily Upside Volatility
60 days
+56.44%
Maximum Daily Downside Volatility
60 days
+42.70%
Liquidity
Average Turnover Rate
60 days
+0.93%
120 days
+0.73%
5 years
--
Turnover Deviation
20 days
+74.02%
60 days
+70.34%
120 days
+33.05%

Peer Comparison

Biotechnology & Medical Research
Aprea Therapeutics Inc
Aprea Therapeutics Inc
APRE
5.42 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.14 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
7.85 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
ACADIA Pharmaceuticals Inc
ACADIA Pharmaceuticals Inc
ACAD
7.67 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Zymeworks Inc
Zymeworks Inc
ZYME
7.64 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Veracyte Inc
Veracyte Inc
VCYT
7.59 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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