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Applied Therapeutics Inc

APLT
0.747USD
-0.143-16.04%
Close 11/06, 16:00ETQuotes delayed by 15 min
106.07MMarket Cap
LossP/E TTM

Applied Therapeutics Inc

0.747
-0.143-16.04%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Applied Therapeutics Inc

Currency: USD Updated: 2025-11-05

Key Insights

The company's fundamentals are relatively very healthy. Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Buy. Despite a very weak market performance, the company shows strong fundamentals and technicals. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Applied Therapeutics Inc's Score

Industry at a Glance

Industry Ranking
116 / 407
Overall Ranking
247 / 4616
Industry
Biotechnology & Medical Research

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 5 analysts
Buy
Current Rating
2.875
Target Price
+184.65%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Applied Therapeutics Inc Highlights

StrengthsRisks
Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company. It is focused on developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need. The Company’s lead drug candidate, govorestat, is a novel central nervous system penetrant Aldose Reductase Inhibitor (ARI) for the treatment of central nervous system (CNS) rare metabolic diseases, including Galactosemia, Sorbitol Dehydrogenase (SORD) Deficiency, and PMM2-CDG. The Company is also developing AT-001, a novel potent ARI, for the treatment of Diabetic Cardiomyopathy (DbCM) a fatal fibrosis of the heart. It has completed a Phase I/II clinical trial evaluating AT-001 in approximately 120 patients with type 2 diabetes, in which no drug-related adverse effects or tolerability issues were observed. The preclinical pipeline also includes AT-003, an ARI designed to cross through the back of the eye when dosed orally, for the treatment of Diabetic retinopathy.
Growing
The company is in a growing phase, with the latest annual income totaling USD 455.00K.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 455.00K.
Fairly Valued
The company’s latest PE is -1.97, at a medium 3-year percentile range.
Institutional Selling
The latest institutional holdings are 91.49M shares, decreasing 37.94% quarter-over-quarter.
Held by The Vanguard
Star Investor The Vanguard holds 4.73M shares of this stock.
Lower Market Activity
The company has less investor interest, with a 20-day turnover ratio of -0.73.

Financial Health

Currency: USD Updated: 2025-11-05

The company's current financial score is 6.83, which is lower than the Biotechnology & Medical Research industry's average of 6.92. Its financial status is robust, and its operating efficiency is low. Its latest quarterly revenue reached 0.00, representing a year-over-year decrease of 100.00%, while its net profit experienced a year-over-year decrease of 836.02%.

Score

Industry at a Glance

Previous score
6.83
Change
0

Financials

10.00

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
No Data

Quality of Earnings

8.04

Operational Efficiency

2.67

Growth Potential

6.39

Shareholder Returns

7.03

Applied Therapeutics Inc's Company Valuation

Currency: USD Updated: 2025-11-05

The company’s current valuation score is 8.00, which is higher than the Biotechnology & Medical Research industry's average of 7.05. Its current P/E ratio is -1.97, which is -82.46% below the recent high of -0.34 and -266.99% above the recent low of -7.21.

Score

Industry at a Glance

Previous score
8.00
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 116/407
No Data

Earnings Forecast

Currency: USD Updated: 2025-11-05

The company’s current earnings forecast score is 7.60, which is lower than the Biotechnology & Medical Research industry's average of 8.00. The average price target for Applied Therapeutics Inc is 2.50, with a high of 5.00 and a low of 1.50.

Score

Industry at a Glance

Previous score
7.60
Change
0

Support & Resistance

No Data

Analyst Rating

Based on 5 analysts
Buy
Current Rating
2.875
Target Price
+223.00%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

521
Total
6
Median
6
Average
Company name
Ratings
Analysts
Applied Therapeutics Inc
APLT
5
CRISPR Therapeutics AG
CRSP
30
Ionis Pharmaceuticals Inc
IONS
25
argenx SE
ARGX
25
Intellia Therapeutics Inc
NTLA
25
IQVIA Holdings Inc
IQV
25
1
2
3
...
104

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-11-05

The company’s current price momentum score is 6.53, which is higher than the Biotechnology & Medical Research industry's average of 6.49. Sideways: Currently, the stock price is trading between the resistance level at 1.30 and the support level at 0.69, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
6.92
Change
-0.39

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(2)
Neutral(2)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.168
Neutral
RSI(14)
34.447
Neutral
STOCH(KDJ)(9,3,3)
3.009
Oversold
ATR(14)
0.152
Low Volatility
CCI(14)
-174.424
Sell
Williams %R
99.761
Oversold
TRIX(12,20)
0.864
Sell
StochRSI(14)
0.000
Oversold
Moving Average
Sell(4)
Neutral(0)
Buy(2)
Indicators
Value
Direction
MA5
0.967
Sell
MA10
1.117
Sell
MA20
1.193
Sell
MA50
0.848
Sell
MA100
0.639
Buy
MA200
0.553
Buy

Institutional Confidence

Currency: USD Updated: 2025-11-05

The company’s current institutional recognition score is 5.00, which is lower than the Biotechnology & Medical Research industry's average of 5.16. The latest institutional shareholding proportion is 63.53%, representing a quarter-over-quarter decrease of 26.81%. The largest institutional shareholder is The Vanguard, holding a total of 4.73M shares, representing 3.29% of shares outstanding, with 18.44% decrease in holdings.

Score

Industry at a Glance

Previous score
5.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
T. Rowe Price Investment Management, Inc.
18.68M
+19.67%
Vestal Point Capital, LP
11.50M
--
Propel Bio Management, LLC
11.29M
--
Knoll Capital Management, LLC
7.80M
--
Alexandria Real Estate Equities, Inc.
5.39M
-5.27%
BlackRock Institutional Trust Company, N.A.
5.04M
-43.75%
The Vanguard Group, Inc.
Star Investors
4.73M
-19.62%
Shendelman (Shoshana)
4.72M
-10.72%
Simplify Asset Management Inc
4.49M
--
Pathstone
2.64M
--
1
2

Risk Assessment

Currency: USD Updated: 2025-11-05

The company’s current risk assessment score is 1.13, which is lower than the Biotechnology & Medical Research industry's average of 3.47. The company's beta value is 1.94. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets.

Score

Industry at a Glance

Previous score
1.13
Change
0
Beta vs S&P 500 index
1.97
VaR
+8.82%
240-Day Maximum Drawdown
+97.06%
240-Day Volatility
+204.43%

Return

Best Daily Return
60 days
+121.35%
120 days
+121.35%
5 years
+121.35%
Worst Daily Return
60 days
-50.65%
120 days
-50.65%
5 years
-76.31%
Sharpe Ratio
60 days
+2.06
120 days
+1.44
5 years
+0.15

Risk Assessment

Maximum Drawdown
240 days
+97.06%
3 years
+97.07%
5 years
+98.95%
Return-to-Drawdown Ratio
240 days
-0.93
3 years
+0.02
5 years
-0.19
Skewness
240 days
+3.04
3 years
+3.15
5 years
+2.73

Volatility

Realised Volatility
240 days
+204.43%
5 years
+139.74%
Standardised True Range
240 days
+14.24%
5 years
+52.05%
Downside Risk-Adjusted Return
120 days
+275.20%
240 days
+275.20%
Maximum Daily Upside Volatility
60 days
+318.08%
Maximum Daily Downside Volatility
60 days
+121.59%

Liquidity

Average Turnover Rate
60 days
+1.11%
120 days
+1.35%
5 years
--
Turnover Deviation
20 days
-73.01%
60 days
-47.66%
120 days
-36.24%

Peer Comparison

Biotechnology & Medical Research
Applied Therapeutics Inc
Applied Therapeutics Inc
APLT
6.35 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
CytomX Therapeutics Inc
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CTMX
8.54 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
NewAmsterdam Pharma Company NV
NewAmsterdam Pharma Company NV
NAMS
8.53 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
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BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.53 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Insmed Inc
Insmed Inc
INSM
8.50 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Amicus Therapeutics Inc
Amicus Therapeutics Inc
FOLD
8.49 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
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