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Apellis Pharmaceuticals Inc

APLS

23.010USD

-0.370-1.58%
Close 09/19, 16:00ETQuotes delayed by 15 min
2.90BMarket Cap
LossP/E TTM

Apellis Pharmaceuticals Inc

23.010

-0.370-1.58%

TradingKey Stock Score

Overall Financial Health

Valuation Dimensions

Earnings Forecast

Price Momentum

Institutional Confidence

Risk Assessment

Peer Comparison

TradingKey Stock Score

Overall Financial Health

Valuation Dimensions

Earnings Forecast

Price Momentum

Institutional Confidence

Risk Assessment

Peer Comparison

TradingKey Stock Score

Currency: USD Updated: 2025-09-19

Key Insights

The company's fundamentals are relatively healthy. Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Buy. The company is performing strongly in the stock market, with strong fundamentals and technicals supporting the momentum. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Industry Ranking
55 / 175
Overall Ranking
180 / 4720
Industry
Pharmaceuticals

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 21 analysts
Buy
Current Rating
37.778
Target Price
+61.58%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Company Highlights

StrengthsRisks
Apellis Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on the discovery, development and commercialization of novel therapeutic compounds to treat diseases with high unmet needs through the inhibition of the complement system. SYFOVRE (pegcetacoplan injection) is the Company’s approved treatment for geographic atrophy secondary to age-related macular degeneration (GA). Its EMPAVELI (pegcetacoplan), is for the treatment of paroxysmal nocturnal hemoglobinuria (PNH). Its Aspaveli (pegcetacoplan) for the treatment of adults with PNH who are anemic after treatment with a C5 inhibitor for at least three months. Systemic pegcetacoplan has also been approved for the treatment of PNH in Japan, Saudi Arabia, Australia, the United Kingdom and other jurisdictions. Systemic pegcetacoplan is marketed under the trade name EMPAVELI in the United States, Saudi Arabia and Australia and Aspaveli in the European Union, Japan and United Kingdom.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 935.99% year-on-year.
Fairly Valued
The company’s latest PE is -12.63, at a medium 3-year percentile range.
Institutional Selling
The latest institutional holdings are 147.96M shares, decreasing 10.18% quarter-over-quarter.
Held by The Vanguard
Star Investor The Vanguard holds 10.14M shares of this stock.

Financial Health

Currency: USD Updated: 2025-09-19

The company's current financial score is 8.25, which is higher than the Pharmaceuticals industry's average of 7.84. Its financial status is stable, and its operating efficiency is high. Its latest quarterly revenue reached 178.49M, representing a year-over-year decrease of 10.61%, while its net profit experienced a year-over-year decrease of 11.93%.

Score

Industry at a Glance

Previous score
8.25
Change
0

Financials

7.92

Key Metrics

Cash and cash equivalents

Total assets

Total liabilities

Free cash flow

No Data

Quality of Earnings

6.65

Operational Efficiency

10.00

Growth Potential

9.20

Shareholder Returns

7.50

Company Valuation

Currency: USD Updated: 2025-09-19

The company’s current valuation score is 1.20, which is lower than the Pharmaceuticals industry's average of 2.06. Its current P/E ratio is -12.83, which is -22.32% below the recent high of -9.97 and -9.30% above the recent low of -14.02.

Score

Industry at a Glance

Previous score
1.20
Change
0

Valuation Dimensions

P/E

P/B

P/S

P/CF

Industry Ranking 55/175
No Data

Earnings Forecast

Currency: USD Updated: 2025-09-19

The company’s current earnings forecast score is 7.71, which is lower than the Pharmaceuticals industry's average of 7.78. The average price target for Apellis Pharmaceuticals Inc is 33.50, with a high of 60.00 and a low of 19.00.

Score

Industry at a Glance

Previous score
7.71
Change
0

Support & Resistance

No Data

Analyst Rating

Based on 21 analysts
Buy
Current Rating
37.778
Target Price
+61.58%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

179
Total
5
Median
8
Average
Company name
Ratings
Analysts
Apellis Pharmaceuticals Inc
APLS
21
Biogen Inc
BIIB
35
Amgen Inc
AMGN
34
Vertex Pharmaceuticals Inc
VRTX
32
Alnylam Pharmaceuticals Inc
ALNY
32
Eli Lilly and Co
LLY
31
1
2
3
...
36

Financial Forecasting

EPS

Revenue

Net Profit

EBIT

No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-09-19

The company’s current price momentum score is 6.22, which is lower than the Pharmaceuticals industry's average of 6.84. Sideways: Currently, the stock price is trading between the resistance level at 27.23 and the support level at 21.26, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
6.22
Change
-0.01

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(2)
Neutral(2)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-1.406
Neutral
RSI(14)
34.472
Neutral
STOCH(KDJ)(9,3,3)
6.645
Oversold
ATR(14)
1.082
Low Volatility
CCI(14)
-106.680
Sell
Williams %R
95.208
Oversold
TRIX(12,20)
-0.159
Sell
StochRSI(14)
5.820
Oversold
Moving Average
Sell(5)
Neutral(0)
Buy(1)
Indicators
Value
Direction
MA5
23.546
Sell
MA10
24.777
Sell
MA20
26.389
Sell
MA50
24.106
Sell
MA100
21.160
Buy
MA200
24.219
Sell

Institutional Confidence

Currency: USD Updated: 2025-09-19

The company’s current institutional recognition score is 10.00, which is higher than the Pharmaceuticals industry's average of 6.26. The latest institutional shareholding proportion is 117.16%, representing a quarter-over-quarter decrease of 0.27%. The largest institutional shareholder is The Vanguard, holding a total of 10.14M shares, representing 8.03% of shares outstanding, with 0.43% decrease in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
Morningside Venture Investments, Ltd.
12.81M
--
Avoro Capital Advisors LLC
12.22M
--
EcoR1 Capital, LLC
11.90M
+0.04%
The Vanguard Group, Inc.
Star Investors
10.11M
+0.84%
Wellington Management Company, LLP
12.30M
+4.26%
Morgan Stanley & Co. LLC
8.10M
+0.51%
Deep Track Capital LP
7.00M
+40.00%
AQR Capital Management, LLC
4.08M
+119.64%
BlackRock Institutional Trust Company, N.A.
5.43M
-0.15%
UBS Financial Services, Inc.
3.27M
+29.40%
1
2

Risk Assessment

Currency: USD Updated: 2025-09-19

The company’s current risk assessment score is 3.22, which is lower than the Pharmaceuticals industry's average of 4.07. The company's beta value is 0.70. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets.

Score

Industry at a Glance

Previous score
3.22
Change
0
Beta vs S&P 500 index
0.71
VaR
+5.23%
240-Day Maximum Drawdown
+53.81%
240-Day Volatility
+60.36%
Return
Best Daily Return
60 days
+17.58%
120 days
+17.58%
5 years
+30.17%
Worst Daily Return
60 days
-5.27%
120 days
-11.32%
5 years
-37.92%
Sharpe Ratio
60 days
+2.26
120 days
+0.23
5 years
+0.11
Risk Assessment
Maximum Drawdown
240 days
+53.81%
3 years
+82.47%
5 years
+82.47%
Return-to-Drawdown Ratio
240 days
-0.33
3 years
-0.24
5 years
-0.13
Skewness
240 days
+0.48
3 years
-0.52
5 years
-0.67
Volatility
Realised Volatility
240 days
+60.36%
5 years
+71.63%
Standardised True Range
240 days
+5.30%
5 years
+11.02%
Downside Risk-Adjusted Return
120 days
+41.58%
240 days
+41.58%
Maximum Daily Upside Volatility
60 days
+56.98%
Maximum Daily Downside Volatility
60 days
+32.12%
Liquidity
Average Turnover Rate
60 days
+1.84%
120 days
+1.98%
5 years
--
Turnover Deviation
20 days
+3.99%
60 days
+5.32%
120 days
+13.13%

Peer Comparison

Pharmaceuticals
Apellis Pharmaceuticals Inc
Apellis Pharmaceuticals Inc
APLS
6.35 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Royalty Pharma PLC
Royalty Pharma PLC
RPRX
8.01 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
United Therapeutics Corp
United Therapeutics Corp
UTHR
7.91 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Neurocrine Biosciences Inc
Neurocrine Biosciences Inc
NBIX
7.79 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Regeneron Pharmaceuticals Inc
Regeneron Pharmaceuticals Inc
REGN
7.77 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Supernus Pharmaceuticals Inc
Supernus Pharmaceuticals Inc
SUPN
7.71 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more
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