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Apellis Pharmaceuticals Inc

APLS
16.970USD
-0.670-3.80%
Close 03/27, 16:00ETQuotes delayed by 15 min
835.89MMarket Cap
95.62P/E TTM

Apellis Pharmaceuticals Inc

16.970
-0.670-3.80%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Apellis Pharmaceuticals Inc

Currency: USD Updated: 2026-03-27

Key Insights

Apellis Pharmaceuticals Inc's fundamentals are relatively very healthy, with an industry-leading ESG disclosure.and its growth potential is high.Its valuation is considered fairly valued, ranking 53 out of 157 in the Pharmaceuticals industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 33.50.In the medium term, the stock price is expected to trend down.Despite a very weak stock market performance over the past month, the company shows strong fundamentals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Apellis Pharmaceuticals Inc's Score

Industry at a Glance

Industry Ranking
53 / 157
Overall Ranking
142 / 4542
Industry
Pharmaceuticals

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Positive

Apellis Pharmaceuticals Inc Highlights

StrengthsRisks
Apellis Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is focused on the discovery, development and commercialization of novel therapeutic compounds to treat diseases with high unmet needs through the inhibition of the complement system. SYFOVRE (pegcetacoplan injection) is the Company’s approved treatment for geographic atrophy secondary to age-related macular degeneration (GA). Its EMPAVELI (pegcetacoplan) is for the treatment of paroxysmal nocturnal hemoglobinuria (PNH). Its Aspaveli (pegcetacoplan) for the treatment of adults with PNH who are anemic after treatment with a C5 inhibitor for at least three months. Systemic pegcetacoplan has also been approved for the treatment of PNH in Japan, Saudi Arabia, Australia, the United Kingdom and other jurisdictions. Systemic pegcetacoplan is marketed under the trade name EMPAVELI in the United States, Saudi Arabia and Australia and Aspaveli in the European Union, Japan and the United Kingdom.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 153.10% year-on-year.
Turnaround to Profit
The company's performance has turned profitable, with the latest annual net income of USD .
Overvalued
The company’s latest PE is 95.62, at a high 3-year percentile range.
Institutional Buying
The latest institutional holdings are 131.04M shares, increasing 3.30% quarter-over-quarter.
Held by Joel Greenblatt
Star Investor Joel Greenblatt holds 168.46K shares of this stock.

Analyst Rating

Based on 24 analysts
Buy
Current Rating
33.500
Target Price
+89.91%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-03-27

The current financial score of Apellis Pharmaceuticals Inc is 8.10, ranking 72 out of 157 in the Pharmaceuticals industry. Its financial status is robust, and its operating efficiency is high. Its latest quarterly revenue reached 199.91M, representing a year-over-year decrease of 5.94%, while its net profit experienced a year-over-year decrease of 62.16%.

Score

Industry at a Glance

Previous score
8.10
Change
0

Financials

8.21

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.04

Operational Efficiency

9.89

Growth Potential

8.03

Shareholder Returns

7.34

Apellis Pharmaceuticals Inc's Company Valuation

Currency: USD Updated: 2026-03-27

The current valuation score of Apellis Pharmaceuticals Inc is 7.55, ranking 64 out of 157 in the Pharmaceuticals industry. Its current P/E ratio is 95.62, which is 27.52% below the recent high of 121.93 and 122.68% above the recent low of -21.68.

Score

Industry at a Glance

Previous score
7.55
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 53/157
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-03-27

The current earnings forecast score of Apellis Pharmaceuticals Inc is 7.74, ranking 96 out of 157 in the Pharmaceuticals industry. The average price target is 36.00, with a high of 55.00 and a low of 19.00.

Score

Industry at a Glance

Previous score
7.74
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 24 analysts
Buy
Current Rating
33.500
Target Price
+89.91%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

174
Total
6
Median
8
Average
Company name
Ratings
Analysts
Apellis Pharmaceuticals Inc
APLS
24
Biogen Inc
BIIB
37
Amgen Inc
AMGN
37
Eli Lilly and Co
LLY
35
Vertex Pharmaceuticals Inc
VRTX
34
Gilead Sciences Inc
GILD
32
1
2
3
...
35

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-03-27

The current price momentum score of Apellis Pharmaceuticals Inc is 5.53, ranking 138 out of 157 in the Pharmaceuticals industry. Currently, the stock price is trading between the resistance level at 19.70 and the support level at 15.54, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
5.85
Change
-0.32

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(4)
Neutral(2)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.119
Sell
RSI(14)
29.424
Sell
STOCH(KDJ)(9,3,3)
16.911
Neutral
ATR(14)
0.734
High Vlolatility
CCI(14)
-95.054
Neutral
Williams %R
95.748
Oversold
TRIX(12,20)
-0.883
Sell
StochRSI(14)
28.265
Sell
Moving Average
Sell(6)
Neutral(0)
Buy(0)
Indicators
Value
Direction
MA5
17.426
Sell
MA10
17.789
Sell
MA20
18.759
Sell
MA50
20.752
Sell
MA100
21.698
Sell
MA200
22.440
Sell

Institutional Confidence

Currency: USD Updated: 2026-03-27

The current institutional shareholding score of Apellis Pharmaceuticals Inc is 10.00, ranking 1 out of 157 in the Pharmaceuticals industry. The latest institutional shareholding proportion is 116.63%, representing a quarter-over-quarter decrease of 1.58%. The largest institutional shareholder is The Vanguard, holding a total of 10.66M shares, representing 8.34% of shares outstanding, with 3.61% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Morningside Venture Investments, Ltd.
12.81M
--
Wellington Management Company, LLP
13.75M
+48.00%
Avoro Capital Advisors LLC
12.22M
--
The Vanguard Group, Inc.
Star Investors
9.97M
-1.65%
Morgan Stanley & Co. LLC
9.19M
+21.33%
Deep Track Capital LP
8.00M
+14.29%
BlackRock Institutional Trust Company, N.A.
5.34M
-2.51%
State Street Investment Management (US)
4.04M
+13.33%
Suvretta Capital Management, LLC
2.88M
--
1
2

Risk Assessment

Currency: USD Updated: 2026-03-27

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Pharmaceuticals domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Apellis Pharmaceuticals Inc is 4.55, ranking 86 out of 157 in the Pharmaceuticals industry. The company's beta value is 0.36. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets. Apellis Pharmaceuticals Inc’s latest ESG disclosure leads the Pharmaceuticals industry, indicating outstanding, compliant performance across environmental management, social responsibility, and governance, which may help mitigate overall risk.

Score

Industry at a Glance

Previous score
4.55
Change
0
Beta vs S&P 500 index
0.40
VaR
+5.17%
240-Day Maximum Drawdown
+43.53%
240-Day Volatility
+59.50%

Return

Best Daily Return
60 days
+10.65%
120 days
+10.65%
5 years
+30.17%
Worst Daily Return
60 days
-15.02%
120 days
-31.01%
5 years
-37.92%
Sharpe Ratio
60 days
-2.58
120 days
-0.53
5 years
-0.03

Risk Assessment

Maximum Drawdown
240 days
+43.53%
3 years
+82.47%
5 years
+82.47%
Return-to-Drawdown Ratio
240 days
-0.29
3 years
-0.33
5 years
-0.17
Skewness
240 days
-1.43
3 years
-1.07
5 years
-1.04

Volatility

Realised Volatility
240 days
+59.50%
5 years
+71.76%
Standardised True Range
240 days
+6.34%
5 years
+14.20%
Downside Risk-Adjusted Return
120 days
-56.25%
240 days
-56.25%
Maximum Daily Upside Volatility
60 days
+39.81%
Maximum Daily Downside Volatility
60 days
+48.80%

Liquidity

Average Turnover Rate
60 days
+1.84%
120 days
+1.98%
5 years
--
Turnover Deviation
20 days
+3.99%
60 days
+5.32%
120 days
+13.13%

Peer Comparison

Pharmaceuticals
Apellis Pharmaceuticals Inc
Apellis Pharmaceuticals Inc
APLS
7.27 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
United Therapeutics Corp
United Therapeutics Corp
UTHR
8.81 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Innoviva Inc
Innoviva Inc
INVA
8.56 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Mckesson Corp
Mckesson Corp
MCK
8.40 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Catalyst Pharmaceuticals Inc
Catalyst Pharmaceuticals Inc
CPRX
8.37 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Jazz Pharmaceuticals PLC
Jazz Pharmaceuticals PLC
JAZZ
8.35 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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