Annovis Bio Inc
ANVS3.660USD
-0.010-0.27%
Close 12/19, 16:00（ET）Quotes delayed by 15 min
73.89MMarket Cap
LossP/E TTM
More Details of Annovis Bio Inc Company
Annovis Bio, Inc. is a late-stage clinical drug platform company addressing neurodegeneration such as Alzheimer’s disease (AD), and Parkinson’s disease (PD). The Company is developing its lead product candidate, Buntanetap, which is designed to address AD, PD, and potentially other chronic neurodegenerative diseases. Buntanetap is a synthetically produced small molecule, orally administered, brain penetrant compound. Its product candidate ANVS405 is an intravenous drug being developed for acute indications and focused on protecting the brain after traumatic brain injury and/or stroke. ANVS405 is the same compound as Buntanetap, given in cases of acute head and brain trauma. ANVS301 is an orally administered drug being developed to increase cognitive capability in later stages of AD and dementia. ANVS301 is observed to improve memory and learning in very old rats by lowering the number of errors from over six to three.
Annovis Bio Inc Info
Ticker SymbolANVS
Company nameAnnovis Bio Inc
IPO dateJan 29, 2020
CEOMaccecchini (Maria L)
Number of employees8
Security typeOrdinary Share
Fiscal year-endJan 29
Address101 Lindenwood Drive, Suite 225
CityMALVERN
Stock exchangeNASDAQ OMX NASDAQ Basic NYSE
CountryUnited States of America
Postal code19355
Phone14848753192
Websitehttps://www.annovisbio.com/
Ticker SymbolANVS
IPO dateJan 29, 2020
CEOMaccecchini (Maria L)
Company Executives of Annovis Bio Inc
Name
Name/Position
Position
Shareholding
Change
Mr. Michael B. Hoffman
Mr. Michael B. Hoffman
Independent Chairman of the Board
Independent Chairman of the Board
2.84M
+1.61%
Dr. Maria L. Maccecchini, Ph.D.
Dr. Maria L. Maccecchini, Ph.D.
President, Chief Executive Officer, Founder, Director
President, Chief Executive Officer, Founder, Director
--
--
Dr. Claudine E. Bruck, Ph.D.
Dr. Claudine E. Bruck, Ph.D.
Independent Director
Independent Director
--
--
Mr. Reid S. Mccarthy
Mr. Reid S. Mccarthy
Independent Director
Independent Director
--
--
Mr. Mark White
Mr. Mark White
Director, Chief Business Officer
Director, Chief Business Officer
--
--
Mr. Mark P. Guerin, CPA
Mr. Mark P. Guerin, CPA
Chief Financial Officer
Chief Financial Officer
--
--
Dr. Mike Christie, Ph.D.
Dr. Mike Christie, Ph.D.
Vice President - Process Chemistry
Vice President - Process Chemistry
--
--
Ms. Eve Damiano
Ms. Eve Damiano
Senior Vice President - Regulatory
Senior Vice President - Regulatory
--
--
Dr. Cheng Fang, Ph.D.
Dr. Cheng Fang, Ph.D.
Senior Vice President - Research and Development
Senior Vice President - Research and Development
--
--
Ms. Melissa Gaines
Ms. Melissa Gaines
Senior Vice President - Clinical Operations
Senior Vice President - Clinical Operations
--
--
Name
Name/Position
Position
Shareholding
Change
Mr. Michael B. Hoffman
Mr. Michael B. Hoffman
Independent Chairman of the Board
Independent Chairman of the Board
2.84M
+1.61%
Dr. Maria L. Maccecchini, Ph.D.
Dr. Maria L. Maccecchini, Ph.D.
President, Chief Executive Officer, Founder, Director
President, Chief Executive Officer, Founder, Director
--
--
Dr. Claudine E. Bruck, Ph.D.
Dr. Claudine E. Bruck, Ph.D.
Independent Director
Independent Director
--
--
Mr. Reid S. Mccarthy
Mr. Reid S. Mccarthy
Independent Director
Independent Director
--
--
Mr. Mark White
Mr. Mark White
Director, Chief Business Officer
Director, Chief Business Officer
--
--
Mr. Mark P. Guerin, CPA
Mr. Mark P. Guerin, CPA
Chief Financial Officer
Chief Financial Officer
--
--
Revenue Breakdown
Relevant data have not been disclosed by the company yet.
Relevant data have not been disclosed by the company yet.
By Business
By Region
Relevant data have not been disclosed by the company yet.
Shareholding Stats
Updated: Thu, Dec 4
Updated: Thu, Dec 4
Shareholders
Shareholder Types
Shareholders
Shareholders
Proportion
Hoffman (Michael B)
10.71%
Maccecchini (Maria-Luisa)
4.57%
Heights Capital Management, Inc.
3.77%
The Vanguard Group, Inc.
2.78%
Susquehanna International Group, LLP
0.82%
Other
77.34%
Shareholders
Shareholders
Proportion
Hoffman (Michael B)
10.71%
Maccecchini (Maria-Luisa)
4.57%
Heights Capital Management, Inc.
3.77%
The Vanguard Group, Inc.
2.78%
Susquehanna International Group, LLP
0.82%
Other
77.34%
Shareholder Types
Shareholders
Proportion
Individual Investor
15.60%
Investment Advisor
8.61%
Investment Advisor/Hedge Fund
1.63%
Hedge Fund
0.70%
Research Firm
0.27%
Venture Capital
0.11%
Family Office
0.05%
Bank and Trust
0.04%
Other
72.99%
Institutional Shareholding
Updated: Mon, Dec 8
Updated: Mon, Dec 8
Reporting Period
No. of institutions
Shares Held
Proportion
Change
2025Q4
95
3.04M
12.65%
--
2025Q3
100
3.04M
19.77%
+213.09K
2025Q2
100
2.82M
20.67%
-295.79K
2025Q1
97
3.12M
17.76%
-341.88K
2024Q4
86
1.59M
13.97%
+377.86K
2024Q3
78
1.21M
12.84%
+189.05K
2024Q2
74
1.03M
17.16%
-257.35K
2024Q1
70
1.29M
17.10%
-594.16K
2023Q4
71
1.27M
17.43%
-328.68K
2023Q3
74
1.16M
17.17%
-74.90K
View more
Shareholder Activity
Name
Shares Held
Proportion
Change
Chg %
Date
Hoffman (Michael B)
1.70M
8.74%
+33.65K
+2.02%
Aug 29, 2025
Maccecchini (Maria-Luisa)
1.11M
5.72%
+46.00K
+4.31%
Jun 04, 2025
Heights Capital Management, Inc.
1.00M
5.13%
--
--
Mar 31, 2025
The Vanguard Group, Inc.
696.76K
3.58%
+48.84K
+7.54%
Jun 30, 2025
Susquehanna International Group, LLP
164.56K
0.84%
+36.85K
+28.86%
Jun 30, 2025
Geode Capital Management, L.L.C.
183.29K
0.94%
+30.67K
+20.10%
Jun 30, 2025
Citadel Advisors LLC
29.33K
0.15%
+29.33K
--
Jun 30, 2025
Northern Trust Investments, Inc.
48.63K
0.25%
+18.84K
+63.21%
Jun 30, 2025
Consilium Associates
91.32K
0.47%
-6.50K
-6.65%
Jun 30, 2025
BlackRock Institutional Trust Company, N.A.
80.67K
0.41%
-18.81K
-18.91%
Jun 30, 2025
View more
Related ETFs
Updated: Sat, Dec 6
Updated: Sat, Dec 6
Name
Proportion
iShares Micro-Cap ETF
0%
iShares Micro-Cap ETF
Proportion0%
Dividend
A total of
0.00
USD has been distributed in dividends over the past 5 years.
Date
Dividend
Record Date
Payment Date
Ex-dividend Date
No Data
Stock Split
Date
Type
Ratio
No Data
Date
Type
Ratio
No Data
FAQs
Who are the top five shareholders of Annovis Bio Inc?
The top five shareholders of Annovis Bio Inc are:
Hoffman (Michael B) holds 1.70M shares, accounting for 8.74% of the total shares.
Maccecchini (Maria-Luisa) holds 1.11M shares, accounting for 5.72% of the total shares.
Heights Capital Management, Inc. holds 1.00M shares, accounting for 5.13% of the total shares.
The Vanguard Group, Inc. holds 696.76K shares, accounting for 3.58% of the total shares.
Susquehanna International Group, LLP holds 164.56K shares, accounting for 0.84% of the total shares.
Hoffman (Michael B) holds 1.70M shares, accounting for 8.74% of the total shares.
Maccecchini (Maria-Luisa) holds 1.11M shares, accounting for 5.72% of the total shares.
Heights Capital Management, Inc. holds 1.00M shares, accounting for 5.13% of the total shares.
The Vanguard Group, Inc. holds 696.76K shares, accounting for 3.58% of the total shares.
Susquehanna International Group, LLP holds 164.56K shares, accounting for 0.84% of the total shares.
What are the top three shareholder types of Annovis Bio Inc?
The top three shareholder types of Annovis Bio Inc are:
Hoffman (Michael B)
Maccecchini (Maria-Luisa)
Heights Capital Management, Inc.
Hoffman (Michael B)
Maccecchini (Maria-Luisa)
Heights Capital Management, Inc.
How many institutions hold shares of Annovis Bio Inc (ANVS)?
As of 2025Q4, 95 institutions hold shares of Annovis Bio Inc, with a combined market value of approximately 3.04M, accounting for 12.65% of the total shares. Compared to 2025Q3, institutional shareholding has increased by -7.11%.
What is the biggest source of revenue for Annovis Bio Inc?
In --, the -- business generated the highest revenue for Annovis Bio Inc, amounting to -- and accounting for --% of total revenue.
