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Annexon Inc

ANNX

2.640USD

+0.120+4.76%
Close 09/18, 16:00ETQuotes delayed by 15 min
289.96MMarket Cap
LossP/E TTM

Annexon Inc

2.640

+0.120+4.76%

TradingKey Stock Score

Overall Financial Health

Valuation Dimensions

Earnings Forecast

Price Momentum

Institutional Confidence

Risk Assessment

Peer Comparison

TradingKey Stock Score

Overall Financial Health

Valuation Dimensions

Earnings Forecast

Price Momentum

Institutional Confidence

Risk Assessment

Peer Comparison

TradingKey Stock Score

Currency: USD Updated2025-09-17

Key Insights

Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Buy. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Industry Ranking
193 / 507
Overall Ranking
340 / 4723
Industry
Biotechnology & Medical Research

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 8 analysts
Buy
Current Rating
11.600
Target Price
+337.74%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Company Highlights

StrengthsRisks
Annexon, Inc. is a clinical-stage biopharmaceutical company. The Company is engaged in advancing a late-stage clinical platform of therapies for people living with classical complement-mediated neuroinflammatory diseases of the body, brain, and eye. Using its platform, it is identifying and characterizing the role of the complement pathway in three therapeutic areas: autoimmune, neurodegeneration and ophthalmology. Its lead candidate, ANX005, is an investigational monoclonal antibody (mAb), formulated for intravenous administration in a pivotal Phase III clinical trial for the treatment of patients with Guillain-Barre Syndrome (GBS). It is evaluating ANX007, an antigen-binding fragment (Fab), formulated for intravitreal administration, for the potential treatment of patients with geographic atrophy (GA). It is developing ANX1502, which is an oral small molecule for the treatment of autoimmune indications. It has developed ANX009, a C1q-blocking Fab formulated for subcutaneous delivery.
Fairly Valued
The company’s latest PE is -1.96, at a medium 3-year percentile range.
Institutional Selling
The latest institutional holdings are 116.41M shares, decreasing 14.12% quarter-over-quarter.
Held by The Vanguard
Star Investor The Vanguard holds 5.37M shares of this stock.

Financial Health

Currency: USD Updated2025-09-17

There is no financial score for this company; the Biotechnology & Medical Research industry's average is 6.93.

Score

Industry at a Glance

Previous score
0.00
Change
0

Financials

Key Metrics

Cash and cash equivalents

Total assets

Total liabilities

Free cash flow

No Data

Quality of Earnings

Operational Efficiency

Growth Potential

Shareholder Returns

Company Valuation

Currency: USD Updated2025-09-17

The company’s current valuation score is 2.80, which is lower than the Biotechnology & Medical Research industry's average of 3.06. Its current P/E ratio is -1.96, which is -10.61% below the recent high of -1.76 and -60.18% above the recent low of -3.15.

Score

Industry at a Glance

Previous score
2.00
Change
0.8

Valuation Dimensions

P/E

P/B

P/S

P/CF

Industry Ranking 193/507
No Data

Earnings Forecast

Currency: USD Updated2025-09-17

The company’s current earnings forecast score is 8.50, which is higher than the Biotechnology & Medical Research industry's average of 8.03. The average price target for Annexon Inc is 11.00, with a high of 14.00 and a low of 9.00.

Score

Industry at a Glance

Previous score
8.50
Change
0

Support & Resistance

No Data

Analyst Rating

Based on 8 analysts
Buy
Current Rating
11.600
Target Price
+360.32%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

554
Total
5
Median
6
Average
Company name
Ratings
Analysts
Annexon Inc
ANNX
8
CRISPR Therapeutics AG
CRSP
30
Ionis Pharmaceuticals Inc
IONS
26
Intellia Therapeutics Inc
NTLA
26
Exact Sciences Corp
EXAS
26
IQVIA Holdings Inc
IQV
25
1
2
3
...
111

Financial Forecasting

EPS

Revenue

Net Profit

EBIT

No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated2025-09-17

The company’s current price momentum score is 6.69, which is higher than the Biotechnology & Medical Research industry's average of 6.32. Sideways: Currently, the stock price is trading between the resistance level at 2.81 and the support level at 2.13, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
7.96
Change
-1.27

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(1)
Neutral(2)
Buy(3)
Indicators
Value
Direction
MACD(12,26,9)
0.121
Buy
RSI(14)
61.070
Neutral
STOCH(KDJ)(9,3,3)
81.328
Neutral
ATR(14)
0.168
High Vlolatility
CCI(14)
105.675
Buy
Williams %R
10.294
Overbought
TRIX(12,20)
0.234
Sell
StochRSI(14)
68.363
Buy
Moving Average
Sell(1)
Neutral(0)
Buy(5)
Indicators
Value
Direction
MA5
2.544
Buy
MA10
2.406
Buy
MA20
2.270
Buy
MA50
2.372
Buy
MA100
2.295
Buy
MA200
2.851
Sell

Institutional Confidence

Currency: USD Updated2025-09-17

The company’s current institutional recognition score is 10.00, which is higher than the Biotechnology & Medical Research industry's average of 5.96. The latest institutional shareholding proportion is 106.10%, representing a quarter-over-quarter increase of 4.27%. The largest institutional shareholder is The Vanguard, holding a total of 5.37M shares, representing 4.88% of shares outstanding, with 5.87% decrease in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
Fidelity Management & Research Company LLC
13.26M
-6.76%
Alerce Investment Management, L.P.
7.41M
--
BlackRock Institutional Trust Company, N.A.
7.62M
+0.73%
BVF Partners L.P.
7.00M
--
Redmile Group, LLC
6.30M
--
The Vanguard Group, Inc.
Star Investors
5.36M
-3.02%
Bain Capital Life Sciences Investors, LLC
5.25M
--
Bellevue Asset Management AG
5.16M
--
Sio Capital Management, LLC
3.40M
+43.55%
1
2

Risk Assessment

Currency: USD Updated2025-09-17

The company’s current risk assessment score is 3.01, which is lower than the Biotechnology & Medical Research industry's average of 3.33. The company's beta value is 1.31. This indicates that the stock tends to outperform the index during upward trending markets but experiences larger declines during downward trending markets.

Score

Industry at a Glance

Previous score
3.01
Change
0
Beta vs S&P 500 index
1.30
VaR
+7.79%
240-Day Maximum Drawdown
+81.91%
240-Day Volatility
+92.71%
Return
Best Daily Return
60 days
+13.77%
120 days
+15.07%
5 years
+35.71%
Worst Daily Return
60 days
-8.46%
120 days
-14.22%
5 years
-59.38%
Sharpe Ratio
60 days
+0.94
120 days
+0.77
5 years
-0.06
Risk Assessment
Maximum Drawdown
240 days
+81.91%
3 years
+82.33%
5 years
+96.06%
Return-to-Drawdown Ratio
240 days
-0.72
3 years
-0.17
5 years
-0.19
Skewness
240 days
+0.33
3 years
-0.40
5 years
-0.22
Volatility
Realised Volatility
240 days
+92.71%
5 years
+99.00%
Standardised True Range
240 days
+9.42%
5 years
+25.09%
Downside Risk-Adjusted Return
120 days
+137.78%
240 days
+137.78%
Maximum Daily Upside Volatility
60 days
+72.03%
Maximum Daily Downside Volatility
60 days
+75.37%
Liquidity
Average Turnover Rate
60 days
+1.34%
120 days
+1.49%
5 years
--
Turnover Deviation
20 days
-32.38%
60 days
-19.50%
120 days
-10.81%

Peer Comparison

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Annexon Inc
Annexon Inc
ANNX
4.76 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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Krystal Biotech Inc
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8.13 /10
Score
Financial Health
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Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
7.85 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
ACADIA Pharmaceuticals Inc
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ACAD
7.65 /10
Score
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Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
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Zymeworks Inc
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7.61 /10
Score
Financial Health
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Earnings Forecast
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Stoke Therapeutics Inc
Stoke Therapeutics Inc
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7.55 /10
Score
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