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Amylyx Pharmaceuticals Inc

AMLX
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13.285USD
-0.595-4.29%
Close 05/15, 16:00ETQuotes delayed by 15 min
1.48BMarket Cap
LossP/E TTM

Amylyx Pharmaceuticals Inc

13.285
-0.595-4.29%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Amylyx Pharmaceuticals Inc

Currency: USD Updated: 2026-05-15

Key Insights

Amylyx Pharmaceuticals Inc's fundamentals are relatively weak, with industry-average ESG disclosure.and its growth potential is high.Its valuation is considered fairly valued, ranking 71 out of 382 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 23.40.In the medium term, the stock price is expected to remain stable.Despite a very weak stock market performance over the past month, the company shows strong technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Amylyx Pharmaceuticals Inc's Score

Industry at a Glance

Industry Ranking
71 / 382
Overall Ranking
184 / 4482
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Negative

Amylyx Pharmaceuticals Inc Highlights

StrengthsRisks
Amylyx Pharmaceuticals, Inc. is a clinical-stage pharmaceutical company. The Company is focused on three investigational therapies across several neurodegenerative and endocrine diseases. Its lead investigational asset is avexitide, an investigational, first-in-class glucagon-like peptide-1 (GLP-1) receptor antagonist. Avexitide has been evaluated as a treatment for Post-Bariatric Hypoglycemia (PBH) and congenital HI, two indications characterized by hyperinsulinemic hypoglycemia. In addition to avexitide, it is advancing AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol in Wolfram syndrome and progressive supranuclear palsy (PSP), and AMX0114 in amyotrophic lateral sclerosis (ALS). AMX0035 is designed to mitigate neurodegeneration by targeting endoplasmic reticulum stress and mitochondrial dysfunction, two cellular processes central to neuronal cell death and neurodegeneration. AMX0114 is an investigational antisense oligonucleotide.
Undervalued
The company’s latest PE is -8.95, at a low 3-year percentile range.
Institutional Selling
The latest institutional holdings are 115.74M shares, decreasing 6.89% quarter-over-quarter.
Held by James Simons
Star Investor James Simons holds 192.50K shares of this stock.

Analyst Rating

Based on 12 analysts
Buy
Current Rating
23.400
Target Price
+68.59%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-05-15

The current financial score of Amylyx Pharmaceuticals Inc is 5.42, ranking 359 out of 382 in the Biotechnology & Medical Research industry. Its financial status is weak, and its operating efficiency is low.

Score

Industry at a Glance

Previous score
5.42
Change
0

Financials

2.66

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.75

Operational Efficiency

2.97

Growth Potential

6.68

Shareholder Returns

7.03

Amylyx Pharmaceuticals Inc's Company Valuation

Currency: USD Updated: 2026-05-15

The current valuation score of Amylyx Pharmaceuticals Inc is 6.11, ranking 318 out of 382 in the Biotechnology & Medical Research industry. Its current P/E ratio is -8.95, which is -4787.36% below the recent high of 419.35 and -121.41% above the recent low of -19.81.

Score

Industry at a Glance

Previous score
6.11
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 71/382
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-05-15

The current earnings forecast score of Amylyx Pharmaceuticals Inc is 8.83, ranking 51 out of 382 in the Biotechnology & Medical Research industry. The average price target is 20.00, with a high of 25.00 and a low of 16.00.

Score

Industry at a Glance

Previous score
8.83
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 12 analysts
Buy
Current Rating
23.400
Target Price
+68.59%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

554
Total
5
Median
6
Average
Company name
Ratings
Analysts
Amylyx Pharmaceuticals Inc
AMLX
12
CRISPR Therapeutics AG
CRSP
27
Beigene Ltd
ONC
26
argenx SE
ARGX
26
IQVIA Holdings Inc
IQV
26
Ionis Pharmaceuticals Inc
IONS
25
1
2
3
...
111

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-05-15

The current price momentum score of Amylyx Pharmaceuticals Inc is 6.56, ranking 223 out of 382 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 16.60 and the support level at 11.57, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
6.49
Change
0.07

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(3)
Neutral(1)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
-0.742
Sell
RSI(14)
30.092
Neutral
STOCH(KDJ)(9,3,3)
4.725
Oversold
ATR(14)
0.846
Low Volatility
CCI(14)
-157.580
Sell
Williams %R
97.380
Oversold
TRIX(12,20)
-0.393
Sell
StochRSI(14)
0.000
Oversold
Moving Average
Sell(6)
Neutral(0)
Buy(0)
Indicators
Value
Direction
MA5
14.213
Sell
MA10
14.994
Sell
MA20
15.889
Sell
MA50
15.357
Sell
MA100
14.603
Sell
MA200
13.422
Sell

Institutional Confidence

Currency: USD Updated: 2026-05-15

The current institutional shareholding score of Amylyx Pharmaceuticals Inc is 10.00, ranking 1 out of 382 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 104.12%, representing a quarter-over-quarter increase of 5.01%. The largest institutional shareholder is Steven Cohen, holding a total of 335.00K shares, representing 0.30% of shares outstanding, with 70.71% decrease in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Fidelity Management & Research Company LLC
14.93M
+33.68%
Perceptive Advisors LLC
8.28M
-7.46%
BlackRock Institutional Trust Company, N.A.
7.48M
+24.29%
TCG Crossover Management, LLC
6.24M
--
Commodore Capital LP
5.65M
--
Saturn V Capital Management LP
4.50M
-2.35%
Janus Henderson Investors
4.47M
+76.08%
Klee (Justin B)
3.58M
+6.53%
Cohen (Joshua Barry)
3.58M
+6.53%
1
2

Risk Assessment

Currency: USD Updated: 2026-05-15

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Amylyx Pharmaceuticals Inc is 5.25, ranking 48 out of 382 in the Biotechnology & Medical Research industry. The company's beta value is -0.14. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets. Amylyx Pharmaceuticals Inc’s latest ESG disclosure is at an average level in the Biotechnology & Medical Research industry, showing no material impact on overall risk.

Score

Industry at a Glance

Previous score
5.25
Change
0
Beta vs S&P 500 index
-0.16
VaR
--
240-Day Maximum Drawdown
+27.93%
240-Day Volatility
+68.95%

Return

Best Daily Return
60 days
+8.93%
120 days
+15.73%
5 years
--
Worst Daily Return
60 days
-7.78%
120 days
-7.78%
5 years
--
Sharpe Ratio
60 days
-0.16
120 days
+0.04
5 years
--

Risk Assessment

Maximum Drawdown
240 days
+27.93%
3 years
+93.09%
5 years
--
Return-to-Drawdown Ratio
240 days
+5.75
3 years
-0.13
5 years
--
Skewness
240 days
+1.53
3 years
-4.35
5 years
--

Volatility

Realised Volatility
240 days
+68.95%
5 years
--
Standardised True Range
240 days
+5.74%
5 years
--
Downside Risk-Adjusted Return
120 days
+8.66%
240 days
+8.66%
Maximum Daily Upside Volatility
60 days
+41.21%
Maximum Daily Downside Volatility
60 days
+38.56%

Liquidity

Average Turnover Rate
60 days
+1.23%
120 days
+1.44%
5 years
--
Turnover Deviation
20 days
-28.38%
60 days
-27.00%
120 days
-14.61%

Peer Comparison

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Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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8.48 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
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8.44 /10
Score
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