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Amylyx Pharmaceuticals Inc

AMLX

13.250USD

+0.480+3.76%
Close 09/18, 16:00ETQuotes delayed by 15 min
1.18BMarket Cap
LossP/E TTM

Amylyx Pharmaceuticals Inc

13.250

+0.480+3.76%

TradingKey Stock Score

Overall Financial Health

Valuation Dimensions

Earnings Forecast

Price Momentum

Institutional Confidence

Risk Assessment

Peer Comparison

TradingKey Stock Score

Overall Financial Health

Valuation Dimensions

Earnings Forecast

Price Momentum

Institutional Confidence

Risk Assessment

Peer Comparison

TradingKey Stock Score

Currency: USD Updated2025-09-17

Key Insights

The company's fundamentals are relatively weak. Its valuation is considered fairly valued,and institutional recognition is very high. Over the past 30 days, multiple analysts have rated the company as a Buy. Despite a very weak stock market performance, the company shows strong technicals. The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Industry Ranking
51 / 507
Overall Ranking
152 / 4723
Industry
Biotechnology & Medical Research

Support & Resistance

No Data

Score Analysis

Current score
Previous score

Analyst Rating

Based on 10 analysts
Buy
Current Rating
14.875
Target Price
+24.37%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Company Highlights

StrengthsRisks
Amylyx Pharmaceuticals, Inc. is a commercial-stage biopharmaceutical company. The Company is engaged in the discovery and development of treatments for neurodegenerative diseases. The Company is focused on the development and commercialization of its product candidate: AMX0035 for the treatment of Wolfram syndrome and for the treatment of progressive supranuclear palsy, and AMX0114, the Company’s antisense oligonucleotide targeting calpain-2 for the treatment of amyotrophic lateral sclerosis (ALS). AMX0035 is a dual-unfolded protein response (UPR)-Bax apoptosis inhibitor composed of PB and TURSO (also known as TUDCA). The Company’s Avexitide is an investigational, first-in-class glucagon-like peptide-1 (GLP-1) receptor antagonist that has been evaluated in five clinical trials for post-bariatric hypoglycemia (PBH) and has also been studied in congenital hyperinsulinism (HI), two indications characterized by hyperinsulinemic hypoglycemia.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 293.03% year-on-year.
Growing
The company is in a growing phase, with the latest annual income totaling USD 87.37M.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 52.11.
Turnaround to Loss
The company's performance has turned to a loss, with the latest annual loss of USD 301.74M.%!(EXTRA int=2)
Fairly Valued
The company’s latest PE is -5.12, at a medium 3-year percentile range.
Institutional Selling
The latest institutional holdings are 88.66M shares, decreasing 6.13% quarter-over-quarter.
Held by Steven Cohen
Star Investor Steven Cohen holds 4.54M shares of this stock.

Financial Health

Currency: USD Updated2025-09-17

The company's current financial score is 5.42, which is lower than the Biotechnology & Medical Research industry's average of 6.93. Its financial status is weak, and its operating efficiency is low. Its latest quarterly revenue reached 0.00, representing a year-over-year increase of 100.00%, while its net profit experienced a year-over-year increase of 42.99%.

Score

Industry at a Glance

Previous score
5.42
Change
0

Financials

2.66

Key Metrics

Cash and cash equivalents

Total assets

Total liabilities

Free cash flow

No Data

Quality of Earnings

7.75

Operational Efficiency

2.97

Growth Potential

6.68

Shareholder Returns

7.03

Company Valuation

Currency: USD Updated2025-09-17

The company’s current valuation score is 2.80, which is lower than the Biotechnology & Medical Research industry's average of 3.06. Its current P/E ratio is -5.12, which is -82.71% below the recent high of -0.89 and -93.69% above the recent low of -9.92.

Score

Industry at a Glance

Previous score
2.00
Change
0.8

Valuation Dimensions

P/E

P/B

P/S

P/CF

Industry Ranking 51/507
No Data

Earnings Forecast

Currency: USD Updated2025-09-17

The company’s current earnings forecast score is 8.80, which is higher than the Biotechnology & Medical Research industry's average of 8.03. The average price target for Amylyx Pharmaceuticals Inc is 13.00, with a high of 25.00 and a low of 10.00.

Score

Industry at a Glance

Previous score
8.80
Change
0

Support & Resistance

No Data

Analyst Rating

Based on 10 analysts
Buy
Current Rating
14.875
Target Price
+16.48%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

554
Total
5
Median
6
Average
Company name
Ratings
Analysts
Amylyx Pharmaceuticals Inc
AMLX
10
CRISPR Therapeutics AG
CRSP
30
Ionis Pharmaceuticals Inc
IONS
26
Intellia Therapeutics Inc
NTLA
26
Exact Sciences Corp
EXAS
26
IQVIA Holdings Inc
IQV
25
1
2
3
...
111

Financial Forecasting

EPS

Revenue

Net Profit

EBIT

No Data

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated2025-09-17

The company’s current price momentum score is 8.93, which is higher than the Biotechnology & Medical Research industry's average of 6.32. Sideways: Currently, the stock price is trading between the resistance level at 14.64 and the support level at 9.36, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
8.66
Change
0.27

Support & Resistance

No Data

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(1)
Neutral(0)
Buy(3)
Indicators
Value
Direction
MACD(12,26,9)
0.418
Buy
RSI(14)
82.101
Overbought
STOCH(KDJ)(9,3,3)
88.392
Overbought
ATR(14)
0.626
High Vlolatility
CCI(14)
124.043
Buy
Williams %R
8.344
Overbought
TRIX(12,20)
1.625
Sell
StochRSI(14)
100.000
Buy
Moving Average
Sell(0)
Neutral(0)
Buy(6)
Indicators
Value
Direction
MA5
12.014
Buy
MA10
11.300
Buy
MA20
10.224
Buy
MA50
8.906
Buy
MA100
7.134
Buy
MA200
5.486
Buy

Institutional Confidence

Currency: USD Updated2025-09-17

The company’s current institutional recognition score is 10.00, which is higher than the Biotechnology & Medical Research industry's average of 5.96. The latest institutional shareholding proportion is 100.38%, representing a quarter-over-quarter decrease of 6.37%. The largest institutional shareholder is Steven Cohen, holding a total of 4.54M shares, representing 4.25% of shares outstanding, with 1.00% increase in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

No Data

Shareholder Activity

Name
Shares Held
Chg %
Adage Capital Management, L.P.
5.70M
--
Perceptive Advisors LLC
7.87M
+16.24%
TCG Crossover Management, LLC
5.94M
+27.99%
BlackRock Institutional Trust Company, N.A.
2.06M
+4.64%
The Vanguard Group, Inc.
Star Investors
4.12M
+52.89%
Klee (Justin B)
3.36M
+7.56%
Cohen (Joshua Barry)
3.36M
+9.80%
Saturn V Capital Management LP
2.43M
+172.92%
1
2

Risk Assessment

Currency: USD Updated2025-09-17

The company’s current risk assessment score is 3.19, which is lower than the Biotechnology & Medical Research industry's average of 3.33. The company's beta value is -0.41. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets.

Score

Industry at a Glance

Previous score
3.19
Change
0
Beta vs S&P 500 index
-0.39
VaR
--
240-Day Maximum Drawdown
+57.33%
240-Day Volatility
+91.60%
Return
Best Daily Return
60 days
+27.69%
120 days
+27.69%
5 years
--
Worst Daily Return
60 days
-8.60%
120 days
-11.11%
5 years
--
Sharpe Ratio
60 days
+4.71
120 days
+3.36
5 years
--
Risk Assessment
Maximum Drawdown
240 days
+57.33%
3 years
+96.04%
5 years
--
Return-to-Drawdown Ratio
240 days
+4.69
3 years
-0.23
5 years
--
Skewness
240 days
+0.83
3 years
-4.63
5 years
--
Volatility
Realised Volatility
240 days
+91.60%
5 years
--
Standardised True Range
240 days
+3.40%
5 years
--
Downside Risk-Adjusted Return
120 days
+689.38%
240 days
+689.38%
Maximum Daily Upside Volatility
60 days
+80.75%
Maximum Daily Downside Volatility
60 days
+40.37%
Liquidity
Average Turnover Rate
60 days
+1.71%
120 days
+1.39%
5 years
--
Turnover Deviation
20 days
-39.17%
60 days
-23.78%
120 days
-37.80%

Peer Comparison

Biotechnology & Medical Research
Amylyx Pharmaceuticals Inc
Amylyx Pharmaceuticals Inc
AMLX
6.64 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Krystal Biotech Inc
Krystal Biotech Inc
KRYS
8.13 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
7.85 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
ACADIA Pharmaceuticals Inc
ACADIA Pharmaceuticals Inc
ACAD
7.65 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Zymeworks Inc
Zymeworks Inc
ZYME
7.61 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Stoke Therapeutics Inc
Stoke Therapeutics Inc
STOK
7.55 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
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