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Akari Therapeutics PLC

AKTX
0.267USD
+0.022+8.93%
Close 12/24, 13:00ETQuotes delayed by 15 min
8.71MMarket Cap
LossP/E TTM

Akari Therapeutics PLC

0.267
+0.022+8.93%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Akari Therapeutics PLC

Currency: USD Updated: 2025-10-27

Key Insights

Its valuation is considered fairly valued, Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at max_target_price.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Akari Therapeutics PLC's Score

Industry at a Glance

Industry Ranking
131 / 173
Overall Ranking
491 / 4682
Industry
Pharmaceuticals

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Analyst Rating

Based on 3 analysts
Buy
Current Rating
4.533
Target Price
+1233.33%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Akari Therapeutics PLC Highlights

StrengthsRisks
Akari Therapeutics, Plc is a biotechnology company developing precision bifunctional antibody drug conjugates (ADC) for the treatment of cancer. Utilizing its ADC discovery platform, it generates bifunctional ADC candidates and optimizes them based on the desired application to target a range of cancers. Its lead candidate, AKTX-101, targets the TROP2 receptor on cancer cells, and with a proprietary linker, delivers its novel PH1 payload directly into the tumor. PH1 is a novel bifunctional payload that is designed to disrupt RNA splicing within cancer cells, inducing tumor-specific cell death while generating immunostimulatory effects and minimizing off-target toxicity. Its pipeline includes AKTX-101 and AKTX-102, a discovery-stage ADC that pairs PH1 with an undisclosed target antibody. It is pursuing research on two additional novel payloads, such as PH5 and PH6. It also has an ADC Platform for oncology and PHP-303 program for genetic disease, liver disease and inflammation.
Undervalued
The company’s latest PE is -3.31, at a low 3-year percentile range.
Institutional Buying
The latest institutional holdings are 562.62K shares, increasing 21.98% quarter-over-quarter.
Held by James Simons
Star Investor James Simons holds 17.41K shares of this stock.

Financial Health

Currency: USD Updated: 2025-10-27

No financial score is currently available for Akari Therapeutics PLC. The Pharmaceuticals industry's average is 7.77.

Score

Industry at a Glance

Previous score
0.00
Change
0

Financials

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

Operational Efficiency

Growth Potential

Shareholder Returns

Akari Therapeutics PLC's Company Valuation

Currency: USD Updated: 2025-10-27

The current valuation score of Akari Therapeutics PLC is 7.49, ranking industry_rank/industry_total in the Pharmaceuticals industry. Its current P/E ratio is -3.31, which is -113.07% below the recent high of 0.43 and -47.30% above the recent low of -4.88.

Score

Industry at a Glance

Previous score
7.49
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 131/173
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2025-10-27

The current earnings forecast score of Akari Therapeutics PLC is 8.00, ranking industry_rank/industry_total in the Pharmaceuticals industry. The average price target for Akari Therapeutics PLC is 5.00, with a high of 7.00 and a low of 1.60.

Score

Industry at a Glance

Previous score
8.00
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 3 analysts
Buy
Current Rating
4.533
Target Price
+1233.33%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

171
Total
6
Median
8
Average
Company name
Ratings
Analysts
Akari Therapeutics PLC
AKTX
3
Biogen Inc
BIIB
36
Amgen Inc
AMGN
35
Eli Lilly and Co
LLY
33
Vertex Pharmaceuticals Inc
VRTX
33
AbbVie Inc
ABBV
32
1
2
3
...
34

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2025-10-27

The current price momentum score of Akari Therapeutics PLC is 4.45, ranking industry_rank/industry_total in the Pharmaceuticals industry. Currently, the stock price is trading between the resistance level at 1.03 and the support level at 0.64, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
4.42
Change
0.03

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(1)
Neutral(3)
Buy(0)
Indicators
Value
Direction
MACD(12,26,9)
0.005
Neutral
RSI(14)
33.622
Neutral
STOCH(KDJ)(9,3,3)
16.876
Oversold
ATR(14)
0.058
High Vlolatility
CCI(14)
-61.119
Neutral
Williams %R
80.412
Oversold
TRIX(12,20)
-2.611
Sell
StochRSI(14)
100.000
Overbought
Moving Average
Sell(5)
Neutral(0)
Buy(1)
Indicators
Value
Direction
MA5
0.256
Buy
MA10
0.300
Sell
MA20
0.338
Sell
MA50
0.526
Sell
MA100
0.717
Sell
MA200
0.971
Sell

Institutional Confidence

Currency: USD Updated: 2025-10-27

The current institutional shareholding score of Akari Therapeutics PLC is 3.00, ranking industry_rank/industry_total in the Pharmaceuticals industry. The latest institutional shareholding proportion is 1.72%, representing a quarter-over-quarter decrease of 95.16%. The largest institutional shareholder is James Simons, holding a total of 17.41K shares, representing 0.05% of shares outstanding, with 44.78% decrease in holdings.

Score

Industry at a Glance

Previous score
3.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
Huh (Hoyoung)
4.70M
+23.48%
Patel (Samir Rashmikant)
2.66M
+56.14%
Prudo-Chlebosz (Raymond)
2.46M
+22.20%
Theofilos (Charles Steve)
1.06M
--
Cresset Asset Management, LLC
18.41K
--
Gaslightwala (Abizer)
262.71K
+8.69%
Palo Alto Investors LP
146.02K
--
Hightower Advisors, LLC
79.24K
--
Bazemore (Robert B)
44.64K
--
1
2

Risk Assessment

Currency: USD Updated: 2025-10-27

No risk assessment score is currently available for Akari Therapeutics PLC. The Pharmaceuticals industry's average is 5.11. The company's beta value is 0.34. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets.

Score

Industry at a Glance

Previous score
0.00
Change
0
Beta vs S&P 500 index
0.27
VaR
+8.22%
240-Day Maximum Drawdown
+83.99%
240-Day Volatility
+139.50%

Return

Best Daily Return
60 days
+13.10%
120 days
+45.96%
5 years
+45.96%
Worst Daily Return
60 days
-38.30%
120 days
-38.30%
5 years
-38.30%
Sharpe Ratio
60 days
-3.51
120 days
-1.85
5 years
-0.80

Risk Assessment

Maximum Drawdown
240 days
+83.99%
3 years
+97.49%
5 years
+99.61%
Return-to-Drawdown Ratio
240 days
-0.93
3 years
-0.33
5 years
-0.20
Skewness
240 days
+0.71
3 years
+0.21
5 years
+0.17

Volatility

Realised Volatility
240 days
+139.50%
5 years
+128.84%
Standardised True Range
240 days
+34.74%
5 years
+326.48%
Downside Risk-Adjusted Return
120 days
-255.82%
240 days
-255.82%
Maximum Daily Upside Volatility
60 days
+128.57%
Maximum Daily Downside Volatility
60 days
+121.74%

Liquidity

Average Turnover Rate
60 days
+0.00%
120 days
+0.00%
5 years
--
Turnover Deviation
20 days
-68.23%
60 days
-81.11%
120 days
-84.83%

Peer Comparison

Pharmaceuticals
Akari Therapeutics PLC
Akari Therapeutics PLC
AKTX
3.91 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Mirum Pharmaceuticals Inc
Mirum Pharmaceuticals Inc
MIRM
8.81 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Gilead Sciences Inc
Gilead Sciences Inc
GILD
8.78 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Regeneron Pharmaceuticals Inc
Regeneron Pharmaceuticals Inc
REGN
8.75 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Collegium Pharmaceutical Inc
Collegium Pharmaceutical Inc
COLL
8.65 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Catalyst Pharmaceuticals Inc
Catalyst Pharmaceuticals Inc
CPRX
8.62 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more

FAQs

How does TradingKey generate the Stock Score of Akari Therapeutics PLC?

The TradingKey Stock Score provides a comprehensive assessment of Akari Therapeutics PLC based on 34 indicators derived from over 100 underlying data points.
These indicators are categorised into six key dimensions: financial health, company profile, earnings forecasts, price momentum, institutional confidence, and risk assessment, collectively providing investors with a thorough analysis of Akari Therapeutics PLC’s performance and outlook.

How do we generate the financial health score of Akari Therapeutics PLC?

To generate the financial health score of Akari Therapeutics PLC, we analyse various key financial indicators across several core dimensions, including financial fundamentals, earnings quality, operational efficiency, growth potential, and shareholder returns.
By integrating these comprehensive data, the financial health score not only reflects Akari Therapeutics PLC's overall stability, operational efficiency, and growth potential but also captures the investment returns delivered to shareholders. This score aims to support rational decision-making for investors and other stakeholders. A higher score indicates a better financial health of Akari Therapeutics PLC.

How do we generate the company valuation score of Akari Therapeutics PLC?

To generate the company valuation score of Akari Therapeutics PLC, we use several key financial ratios, including P/E, P/B, P/S, and P/CF. These metrics compare Akari Therapeutics PLC’s market value to its earnings, assets, sales, and cash flow, serving as core indicators for assessing company value.
By analysing these ratios in an all-round manner, the valuation score reflects not only the market’s current perception of Akari Therapeutics PLC’s value but also its future profitability and growth potential, thereby supporting more informed investment decisions. A higher score indicates a fairer valuation of Akari Therapeutics PLC.

How do we generate the earnings forecast score of Akari Therapeutics PLC?

To calculate the earnings forecast score of Akari Therapeutics PLC, we consider various key indicators such as analyst ratings, financial forecasts, support and resistance levels, and peer comparisons:
Current ratings and price targets directly reflect analysts’ expectations, while the upside space indicates their views on the stock’s growth potential.
Financial metrics like earnings per share (EPS), revenue, net income, and earnings before interest and taxes (EBIT) are core measures for assessing profitability.
By analysing the high, median, and low ranges of the target price, we can identify price trends and determine key support and resistance levels.
Comparing these indicators against peers provides context for the stock’s performance and helps anchor more realistic expectations.
These factors together form a comprehensive earnings forecast score that accurately reflects the stock’s expected financial performance and growth potential. A higher score suggests that analysts have a more optimistic outlook on Akari Therapeutics PLC’s future.

How do we generate the price momentum score of Akari Therapeutics PLC?

When generating the price momentum score for Akari Therapeutics PLC, we examine momentum indicators including support and resistance levels as well as volume metrics.
Support levels represent price points where buying interest is strong enough to prevent further declines, while resistance levels indicate prices where selling pressure may hinder upward movement. By analysing typical price volume alongside total volume, we assess overall market activity and liquidity. These indicators help identify price trends and potential shifts, enabling more accurate predictions of future earnings.
This comprehensive approach can reflect market sentiment and enable rational forecasts of Akari Therapeutics PLC’s prices. A higher score indicates a more stable short-term price trend for Akari Therapeutics PLC.

How do we generate the institutional confidence score of Akari Therapeutics PLC?

To generate the institutional confidence score of Akari Therapeutics PLC, we analyse both the proportion of shares held by institutions and the number of shares they own. A higher institutional ownership percentage indicates strong confidence of professional investors, which is generally a positive signal about Akari Therapeutics PLC’s potential. By examining the number of shares held, we gain deeper insight into institutions’ commitment and attitude toward the stock, as institutional investors typically conduct thorough analysis before making investment decisions. Understanding institutional confidence helps us refine earnings forecasts and provides a more reliable perspective on the company’s future performance and market stability. A higher score indicates greater institutional endorsement of Akari Therapeutics PLC.

How do we generate the risk management score of Akari Therapeutics PLC?

To assess the risk management score of Akari Therapeutics PLC, we examine multiple key indicators related to returns, risk, volatility, and liquidity.
The highest and lowest daily returns reflect the potential size of gains and losses, while the Sharpe ratio measures risk-adjusted return performance. On the risk side, we analyse maximum drawdown and the return-to-drawdown ratio to identify extreme loss scenarios. Skewness helps assess the distribution of returns and whether performance may be biased. Volatility indicators—such as realised volatility and standardised true range—reveal price fluctuations. Downside risk-adjusted returns provide insight into potential losses and gains. Lastly, liquidity metrics like average turnover rate and turnover deviation indicate how actively the stock is traded.
These indicators together provide a multi-dimensional understanding of Akari Therapeutics PLC’s risk-return profile, serving as core factors of the risk management score. A higher score indicates lower risk on the side of Akari Therapeutics PLC.
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