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Agios Pharmaceuticals Inc

AGIO
29.430USD
-0.520-1.74%
Close 03/27, 16:00ETQuotes delayed by 15 min
1.72BMarket Cap
LossP/E TTM

Agios Pharmaceuticals Inc

29.430
-0.520-1.74%
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison
TradingKey Stock Score
Overall Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Peer Comparison

TradingKey Stock Score of Agios Pharmaceuticals Inc

Currency: USD Updated: 2026-03-27

Key Insights

Agios Pharmaceuticals Inc's fundamentals are relatively healthy, with an industry-leading ESG disclosure.and its growth potential is high.Its valuation is considered fairly valued, ranking 50 out of 391 in the Biotechnology & Medical Research industry.Institutional ownership is very high.Over the past month, multiple analysts have rated it as Buy, with the highest price target at 41.14.In the medium term, the stock price is expected to remain stable.Despite an average stock market performance over the past month, the company shows strong fundamentals and technicals.The stock price is trading sideways between the support and resistance levels, making it suitable for range-bound swing trading.

Agios Pharmaceuticals Inc's Score

Industry at a Glance

Industry Ranking
50 / 391
Overall Ranking
153 / 4542
Industry
Biotechnology & Medical Research

Support & Resistance

Relevant data have not been disclosed by the company yet.

Score Analysis

Current score
Previous score

Media Coverage

Last 24 hours
Coverage Level

Very Low
Very High
Neutral

Agios Pharmaceuticals Inc Highlights

StrengthsRisks
Agios Pharmaceuticals, Inc. is a biopharmaceutical company. The Company is focused on developing and delivering transformative therapies for patients living with rare diseases. It markets a first-in-class pyruvate kinase (PK) activator for adults with PK deficiency, the first disease-modifying therapy for debilitating hemolytic anemia. Its lead product candidate in its portfolio, PYRUKYND (mitapivat), is an activator of both wild-type and mutant pyruvate kinase, or PK, enzymes for the potential treatment of hemolytic anemias. It is also developing tebapivat, a novel PK activator, for the potential treatment of lower-risk myelodysplastic syndromes, or LR MDS, and hemolytic anemias; AG-181, its phenylalanine hydroxylase, or PAH, stabilizer for the potential treatment of phenylketonuria, or PKU; and AG-236, an siRNA in-licensed from Alnylam Pharmaceuticals, Inc., targeting the transmembrane serine protease 6, or TMPRSS6 gene for the potential treatment of polycythemia vera, or PV.
High Growth
The company's revenue has grown steadily over the past 3 years, averaging 101.42% year-on-year.
Growing
The company is in a growing phase, with the latest annual income totaling USD 54.03M.
High Profit Growth
The company's net income leads the industry, with the latest annual income totaling USD 54.03M.
Turnaround to Loss
The company's performance has turned to a loss, with the latest annual loss of USD .
Fairly Valued
The company’s latest PE is -4.13, at a medium 3-year percentile range.
Institutional Buying
The latest institutional holdings are 64.77M shares, increasing 0.00% quarter-over-quarter.
Held by HACAX
Star Investor HACAX holds 37.23K shares of this stock.
Higher Market Activity
The company has more investor interest, with a 20-day turnover ratio of 0.23.

Analyst Rating

Based on 10 analysts
Buy
Current Rating
41.143
Target Price
+45.12%
Upside Space
Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Financial Health

Currency: USD Updated: 2026-03-27

The current financial score of Agios Pharmaceuticals Inc is 6.22, ranking 278 out of 391 in the Biotechnology & Medical Research industry. Its financial status is stable, and its operating efficiency is low. Its latest quarterly revenue reached 19.97M, representing a year-over-year increase of 86.09%, while its net profit experienced a year-over-year increase of 11.93%.

Score

Industry at a Glance

Previous score
6.22
Change
0

Financials

6.63

Key Metrics

Cash and cash equivalents
Total assets
Total liabilities
Free cash flow
Relevant data have not been disclosed by the company yet.

Quality of Earnings

7.63

Operational Efficiency

2.72

Growth Potential

6.99

Shareholder Returns

7.11

Agios Pharmaceuticals Inc's Company Valuation

Currency: USD Updated: 2026-03-27

The current valuation score of Agios Pharmaceuticals Inc is 6.26, ranking 301 out of 391 in the Biotechnology & Medical Research industry. Its current P/E ratio is -4.13, which is -225.68% below the recent high of 5.19 and -87.32% above the recent low of -7.74.

Score

Industry at a Glance

Previous score
6.26
Change
0

Valuation Dimensions

P/E
P/B
P/S
P/CF
Industry Ranking 50/391
Relevant data have not been disclosed by the company yet.

Earnings Forecast

Currency: USD Updated: 2026-03-27

The current earnings forecast score of Agios Pharmaceuticals Inc is 8.00, ranking 163 out of 391 in the Biotechnology & Medical Research industry. The average price target is 32.00, with a high of 48.00 and a low of 20.00.

Score

Industry at a Glance

Previous score
8.00
Change
0

Support & Resistance

Relevant data have not been disclosed by the company yet.

Analyst Rating

Based on 10 analysts
Buy
Current Rating
41.143
Target Price
+45.12%
Upside Space
Strong Buy
Buy
Hold
Sell
Strong Sell

Peer Comparison

548
Total
6
Median
6
Average
Company name
Ratings
Analysts
Agios Pharmaceuticals Inc
AGIO
10
CRISPR Therapeutics AG
CRSP
29
IQVIA Holdings Inc
IQV
27
argenx SE
ARGX
26
Beigene Ltd
ONC
24
Intellia Therapeutics Inc
NTLA
24
1
2
3
...
110

Financial Forecasting

EPS
Revenue
Net Profit
EBIT
Relevant data have not been disclosed by the company yet.

Data disclaimer: Analyst ratings and target prices are provided by LSEG for informational purposes only and do not constitute investment advice.

Price Momentum

Currency: USD Updated: 2026-03-27

The current price momentum score of Agios Pharmaceuticals Inc is 8.69, ranking 33 out of 391 in the Biotechnology & Medical Research industry. Currently, the stock price is trading between the resistance level at 31.25 and the support level at 27.22, making it suitable for range-bound swing trading.

Score

Industry at a Glance

Previous score
8.94
Change
-0.25

Support & Resistance

Relevant data have not been disclosed by the company yet.

Indicators

The Indicators feature provides value and direction analysis for various instruments under a selection of technical indicators, together with a technical summary.

This feature includes nine of the commonly used technical indicators: MACD, RSI, KDJ, StochRSI, ATR, CCI, WR, TRIX and MA. You may also adjust the timeframe depending on your needs.

Please note that technical analysis is only part of investment reference, and there is no absolute standard for using numerical values to assess direction. The results are for reference only, and we are not responsible for the accuracy of the indicator calculations and summaries.

Indicators
Sell(2)
Neutral(2)
Buy(3)
Indicators
Value
Direction
MACD(12,26,9)
0.301
Buy
RSI(14)
57.001
Neutral
STOCH(KDJ)(9,3,3)
63.809
Neutral
ATR(14)
1.084
High Vlolatility
CCI(14)
122.312
Buy
Williams %R
37.209
Buy
TRIX(12,20)
0.031
Sell
StochRSI(14)
64.104
Sell
Moving Average
Sell(2)
Neutral(0)
Buy(4)
Indicators
Value
Direction
MA5
29.086
Buy
MA10
28.709
Buy
MA20
28.421
Buy
MA50
28.280
Buy
MA100
29.490
Sell
MA200
33.810
Sell

Institutional Confidence

Currency: USD Updated: 2026-03-27

The current institutional shareholding score of Agios Pharmaceuticals Inc is 10.00, ranking 1 out of 391 in the Biotechnology & Medical Research industry. The latest institutional shareholding proportion is 127.16%, representing a quarter-over-quarter decrease of 0.48%. The largest institutional shareholder is The Vanguard, holding a total of 5.58M shares, representing 9.52% of shares outstanding, with 1.36% decrease in holdings.

Score

Industry at a Glance

Previous score
10.00
Change
0

Institutional Shareholding

Relevant data have not been disclosed by the company yet.

Shareholder Activity

Name
Shares Held
Chg %
The Vanguard Group, Inc.
Star Investors
5.59M
-1.36%
Farallon Capital Management, L.L.C.
5.78M
+0.24%
BlackRock Institutional Trust Company, N.A.
3.98M
-4.45%
State Street Investment Management (US)
2.26M
+15.97%
Erste Asset Management GmbH
2.76M
+18.84%
Nomura Investment Management Business Trust
1.96M
+3.03%
Geode Capital Management, L.L.C.
1.42M
+0.75%
1
2

Risk Assessment

Currency: USD Updated: 2026-03-27

The U.S. Dollar Index is currently in a neutral state, which has a neutral effect on the Biotechnology & Medical Research domestic-focused industry. The Dollar Index (DXY) measures the value of the U.S. dollar against a basket of major currencies, including the euro, yen, pound sterling, Canadian dollar, Swedish krona, and Swiss franc. The current risk assessment score of Agios Pharmaceuticals Inc is 3.24, ranking 156 out of 391 in the Biotechnology & Medical Research industry. The company's beta value is 0.86. This indicates that the stock tends to underperform the index during upward trending markets but experiences smaller declines during downward trending markets. with an industry-leading ESG disclosure.

Score

Industry at a Glance

Previous score
3.24
Change
0
Beta vs S&P 500 index
0.86
VaR
+4.85%
240-Day Maximum Drawdown
+50.89%
240-Day Volatility
+90.14%

Return

Best Daily Return
60 days
+5.48%
120 days
+18.63%
5 years
+23.21%
Worst Daily Return
60 days
-4.08%
120 days
-50.89%
5 years
-50.89%
Sharpe Ratio
60 days
+1.18
120 days
-0.11
5 years
+0.07

Risk Assessment

Maximum Drawdown
240 days
+50.89%
3 years
+63.76%
5 years
+72.16%
Return-to-Drawdown Ratio
240 days
+0.20
3 years
+0.08
5 years
-0.14
Skewness
240 days
-6.32
3 years
-3.12
5 years
-1.62

Volatility

Realised Volatility
240 days
+90.14%
5 years
+63.41%
Standardised True Range
240 days
+5.37%
5 years
+5.28%
Downside Risk-Adjusted Return
120 days
-9.88%
240 days
-9.88%
Maximum Daily Upside Volatility
60 days
+27.79%
Maximum Daily Downside Volatility
60 days
+22.38%

Liquidity

Average Turnover Rate
60 days
+1.25%
120 days
+1.18%
5 years
--
Turnover Deviation
20 days
+23.33%
60 days
+1.07%
120 days
-5.03%

Peer Comparison

Biotechnology & Medical Research
Agios Pharmaceuticals Inc
Agios Pharmaceuticals Inc
AGIO
7.16 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Alkermes Plc
Alkermes Plc
ALKS
8.42 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Madrigal Pharmaceuticals Inc
Madrigal Pharmaceuticals Inc
MDGL
8.27 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
BioCryst Pharmaceuticals Inc
BioCryst Pharmaceuticals Inc
BCRX
8.27 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
Day One Biopharmaceuticals Inc
Day One Biopharmaceuticals Inc
DAWN
8.26 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
IQVIA Holdings Inc
IQVIA Holdings Inc
IQV
8.21 /10
Score
Financial Health
Valuation Dimensions
Earnings Forecast
Price Momentum
Institutional Confidence
Risk Assessment
View more
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