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Could This 1 Thing That's Happened Only 3 Times in the Past 67 Years Halt the S&P 500's Gains in 2025? Here's What History Says.
This year has been a fantastic one for stocks, from the moment the S&P 500 confirmed a bull market back in January to today, with the three major benchmarks heading for double-digiThe Motley Fool
Thu, Dec 19
This Flaw in the Social Security Benefit Calculation Will Cost Retirees $120 on Average in 2025
In just a few weeks, retirees will get their first Social Security benefits with the 2025 cost-of-living adjustment (COLA) included. This will raise the average check to $1,976 perThe Motley Fool
Thu, Dec 19
MegaPro Medical’s new MRI contrast agent MPB-2043 has completed the first patient admission in Taiwan
A new nanodrug development company - MegaPro Biomedical Co., Ltd. (hereinafter referred to as "MegaPro", Taiwan OTC Stock Code: 6827) announced today that the company's independently developed new drug MPB-2043, an MRI contrast agent for lymph node staging in patients with head and neck squamous cell carcinoma, has completed the admission of the first domestic patient at National Taiwan University Hospital and is currently undergoing an Investigator-Intiated Trial (IIT). It is expected that clinical admissions of the IIT can be completed within the first six months of next year.MegaPro's nanoparticle technology platform has developed MPB-2043, a new imaging agent. This new application is mainly based on the fact that MPB-2043 can be differentially phagocytosed by immune cells, producing high-contrast MRI images for doctors to determine lymph nodes and whether it is metastasized by tumor cells, thereby assisting doctors to more accurately stage cancer cases and formulate correct treatment strategies for patients. This IIT trial is expected to obtain the effectiveness and safety of lymph node staging in patients with head and neck cancer. Since MPB-2043 is also part of a nanoparticle technology platform, relevant clinical phase 1 data can be shared with it, and IIT data will be used to apply for clinical phase II trials to regulatory authorities.Assessing whether lymph nodes have been metastasized by malignant tumors has been an important unmet medical need. According to statistics from The Global Cancer Observatory (GCO) in 2022, it is currently highly required to determine whether lymph nodes have metastasized for cancers such as breast cancer, lung cancer, prostate cancer, gastric cancer, colorectal cancer and head/neck cancer to formulate medical strategies. Currently, the number of new cases of the aforementioned cancers is about 9 million per year, and the number of 5-year survivors exceeds 23 million. The total number of people who would need to use this drug worldwide would exceed 32 million annually.Global regulations have regarded imaging agents as new drugs and are required to conform to the process of new drug development. In the past, MegaPro has used its nanoparticle technology platform to develop the MPB-1523 MRI Imaging Agent - Hepatocellular Carcinoma. This product is currently preparing for questions raised by the US FDA, and it is expected that a phase 3 clinical trial application will be submitted after completion. In addition, the MPB-2043 MRI Imaging Agent - Lymph Node belongs to the nanoparticle technology platform as well. In the future, the development experience and certain data of the MPB-1523 will be used to accelerate clinical trials and drug license applications.19/12/2024 Dissemination of a Financial Press Release, transmitted by EQS News.The issuer is solely responsible for the content of this announcement.Media archive at www.todayir.comEQS
Thu, Dec 19
MegaPro Medical’s new MRI contrast agent MPB-2043 has completed the first patient admission in Taiwan
A new nanodrug development company - MegaPro Biomedical Co., Ltd. (hereinafter referred to as "MegaPro", Taiwan OTC Stock Code: 6827) announced today that the company's independently developed new drug MPB-2043, an MRI contrast agent for lymph node staging in patients with head and neck squamous cell carcinoma, has completed the admission of the first domestic patient at National Taiwan University Hospital and is currently undergoing an Investigator-Intiated Trial (IIT). It is expected that clinical admissions of the IIT can be completed within the first six months of next year.MegaPro's nanoparticle technology platform has developed MPB-2043, a new imaging agent. This new application is mainly based on the fact that MPB-2043 can be differentially phagocytosed by immune cells, producing high-contrast MRI images for doctors to determine lymph nodes and whether it is metastasized by tumor cells, thereby assisting doctors to more accurately stage cancer cases and formulate correct treatment strategies for patients. This IIT trial is expected to obtain the effectiveness and safety of lymph node staging in patients with head and neck cancer. Since MPB-2043 is also part of a nanoparticle technology platform, relevant clinical phase 1 data can be shared with it, and IIT data will be used to apply for clinical phase II trials to regulatory authorities.Assessing whether lymph nodes have been metastasized by malignant tumors has been an important unmet medical need. According to statistics from The Global Cancer Observatory (GCO) in 2022, it is currently highly required to determine whether lymph nodes have metastasized for cancers such as breast cancer, lung cancer, prostate cancer, gastric cancer, colorectal cancer and head/neck cancer to formulate medical strategies. Currently, the number of new cases of the aforementioned cancers is about 9 million per year, and the number of 5-year survivors exceeds 23 million. The total number of people who would need to use this drug worldwide would exceed 32 million annually.Global regulations have regarded imaging agents as new drugs and are required to conform to the process of new drug development. In the past, MegaPro has used its nanoparticle technology platform to develop the MPB-1523 MRI Imaging Agent - Hepatocellular Carcinoma. This product is currently preparing for questions raised by the US FDA, and it is expected that a phase 3 clinical trial application will be submitted after completion. In addition, the MPB-2043 MRI Imaging Agent - Lymph Node belongs to the nanoparticle technology platform as well. In the future, the development experience and certain data of the MPB-1523 will be used to accelerate clinical trials and drug license applications.19/12/2024 Dissemination of a Financial Press Release, transmitted by EQS News.The issuer is solely responsible for the content of this announcement.Media archive at www.todayir.comEQS
Thu, Dec 19
SeaPRwire Expands Media Network and Launches New Solutions in Cambodia
Hong Kong - December 19, 2024 - (SeaPRwire) - SeaPRwire, a leading technology company specializing in press release distribution and earned media communications management, has announced its latest initiative to expand its media network in Cambodia. With the introduction of the Media-Empower-Pack as part of its Branding-Insight Program, SeaPRwire is set to empower businesses and PR professionals in Cambodia and across Southeast Asia.SeaPRwire's Cambodia media network now includes a robust lineup of platforms such as Cambodia Net, See Cambodia, Cambodia Press Release, Khmer Online, Phnom Penh Business, and Visit Khmer. These additions solidify SeaPRwire's presence in the region, ensuring comprehensive coverage for brands seeking impactful media exposure in the Cambodian market.The Media-Empower-Pack brings innovative solutions to the table, providing global press release distribution to over 8,000 media outlets and covering multiple industry-specific lists. With support for multimedia and unlimited word counts, it ensures that companies can communicate their messages effectively and broadly. A key feature of the Media-Empower-Pack is its multilingual capability, accommodating more than 17 languages, including English, French, German, Traditional Chinese, Simplified Chinese, Japanese, Korean, Vietnamese, Indonesian, Filipino, Malay, Thai, Italian, Russian, and more."Our mission is to bridge brands and audiences by delivering strategic media communications," said James Scott, Chief Marketing Officer of SeaPRwire. "With the expansion of our Cambodia media network and the introduction of the Media-Empower-Pack, we aim to provide businesses in Phnom Penh and across Cambodia with the tools they need to succeed in today's competitive landscape."The Branding-Insight Program, powered by the Media-Empower-Pack, enhances the ability of PR and communications professionals to build and manage tailored media lists. With real-time updates, users can effortlessly access contact cards containing essential details such as names, phone numbers, and email addresses of media contacts. The dashboard further allows for seamless customization, enabling users to split, edit, or merge lists for a more targeted approach."Leveraging thought leadership content to reach the right audience at the right time has become a cornerstone of successful media strategies," added Scott. "We ensure that every dollar spent on media and marketing communications yields measurable returns, enabling our clients to achieve their goals. In challenging economic times, utilizing an informative, engaging press release as a marketing tool can be a game-changer for businesses."SeaPRwire's expansion into Cambodia aligns with its broader strategy to support businesses in Southeast Asia. With an increasing focus on Khmer audiences, the company is committed to enabling brands in Phnom Penh and beyond to craft compelling stories that resonate with local and global markets.Scott emphasized the importance of media outreach in driving growth and visibility for companies. "For CEOs, especially in today's economic climate, leveraging effective media strategies can generate significant ROI. Our integrated solutions, like the Branding-Insight Program, are designed to help brands deliver strategic media pitches and earn valuable media mentions."In addition to the Media-Empower-Pack, SeaPRwire provides a suite of tools to support brands in their communications journey. The program enables businesses to track and analyze the performance of their campaigns, ensuring a data-driven approach to media management. With its robust infrastructure and commitment to innovation, SeaPRwire continues to set the benchmark for press release distribution in Asia.Businesses and PR professionals interested in exploring the opportunities offered by SeaPRwire's expanded network in Cambodia or its Branding-Insight Program can learn more by visiting www.SeaPRwire.com. By harnessing the power of media, brands can enhance their visibility, build meaningful connections with their target audience, and drive growth in an increasingly competitive market.About SeaPRwireSeaPRwire (https://www.SeaPRwire.com/) is a leading global provider of wire distribution services to media relations and marketing communications professionals. SeaPRwire's platform allows clients to identify key factors of their press releases and measure meaningful impact. It has a strong media network in Southeast Asia, indexing news from thousands of worldwide sources. SeaPRwire's media network support multi-lingual press release distribution, including English, Chinese, Burmese, Khmer, Laos, Vietnamese, Thai, Malay, Indonesian, Filipino and more. SeaPRwire provides real time press release distribution for companies and organizations to 6,500+ media outlets.Media ContactTina Lee, PR managercs@SeaPRwire.comhttps://www.seaprwire.comSOURCE: SeaPRwire19/12/2024 Dissemination of a Financial Press Release, transmitted by EQS News.The issuer is solely responsible for the content of this announcement.Media archive at www.todayir.comEQS
Thu, Dec 19
SeaPRwire Expands Media Network and Launches New Solutions in Cambodia
Hong Kong - December 19, 2024 - (SeaPRwire) - SeaPRwire, a leading technology company specializing in press release distribution and earned media communications management, has announced its latest initiative to expand its media network in Cambodia. With the introduction of the Media-Empower-Pack as part of its Branding-Insight Program, SeaPRwire is set to empower businesses and PR professionals in Cambodia and across Southeast Asia.SeaPRwire's Cambodia media network now includes a robust lineup of platforms such as Cambodia Net, See Cambodia, Cambodia Press Release, Khmer Online, Phnom Penh Business, and Visit Khmer. These additions solidify SeaPRwire's presence in the region, ensuring comprehensive coverage for brands seeking impactful media exposure in the Cambodian market.The Media-Empower-Pack brings innovative solutions to the table, providing global press release distribution to over 8,000 media outlets and covering multiple industry-specific lists. With support for multimedia and unlimited word counts, it ensures that companies can communicate their messages effectively and broadly. A key feature of the Media-Empower-Pack is its multilingual capability, accommodating more than 17 languages, including English, French, German, Traditional Chinese, Simplified Chinese, Japanese, Korean, Vietnamese, Indonesian, Filipino, Malay, Thai, Italian, Russian, and more."Our mission is to bridge brands and audiences by delivering strategic media communications," said James Scott, Chief Marketing Officer of SeaPRwire. "With the expansion of our Cambodia media network and the introduction of the Media-Empower-Pack, we aim to provide businesses in Phnom Penh and across Cambodia with the tools they need to succeed in today's competitive landscape."The Branding-Insight Program, powered by the Media-Empower-Pack, enhances the ability of PR and communications professionals to build and manage tailored media lists. With real-time updates, users can effortlessly access contact cards containing essential details such as names, phone numbers, and email addresses of media contacts. The dashboard further allows for seamless customization, enabling users to split, edit, or merge lists for a more targeted approach."Leveraging thought leadership content to reach the right audience at the right time has become a cornerstone of successful media strategies," added Scott. "We ensure that every dollar spent on media and marketing communications yields measurable returns, enabling our clients to achieve their goals. In challenging economic times, utilizing an informative, engaging press release as a marketing tool can be a game-changer for businesses."SeaPRwire's expansion into Cambodia aligns with its broader strategy to support businesses in Southeast Asia. With an increasing focus on Khmer audiences, the company is committed to enabling brands in Phnom Penh and beyond to craft compelling stories that resonate with local and global markets.Scott emphasized the importance of media outreach in driving growth and visibility for companies. "For CEOs, especially in today's economic climate, leveraging effective media strategies can generate significant ROI. Our integrated solutions, like the Branding-Insight Program, are designed to help brands deliver strategic media pitches and earn valuable media mentions."In addition to the Media-Empower-Pack, SeaPRwire provides a suite of tools to support brands in their communications journey. The program enables businesses to track and analyze the performance of their campaigns, ensuring a data-driven approach to media management. With its robust infrastructure and commitment to innovation, SeaPRwire continues to set the benchmark for press release distribution in Asia.Businesses and PR professionals interested in exploring the opportunities offered by SeaPRwire's expanded network in Cambodia or its Branding-Insight Program can learn more by visiting www.SeaPRwire.com. By harnessing the power of media, brands can enhance their visibility, build meaningful connections with their target audience, and drive growth in an increasingly competitive market.About SeaPRwireSeaPRwire (https://www.SeaPRwire.com/) is a leading global provider of wire distribution services to media relations and marketing communications professionals. SeaPRwire's platform allows clients to identify key factors of their press releases and measure meaningful impact. It has a strong media network in Southeast Asia, indexing news from thousands of worldwide sources. SeaPRwire's media network support multi-lingual press release distribution, including English, Chinese, Burmese, Khmer, Laos, Vietnamese, Thai, Malay, Indonesian, Filipino and more. SeaPRwire provides real time press release distribution for companies and organizations to 6,500+ media outlets.Media ContactTina Lee, PR managercs@SeaPRwire.comhttps://www.seaprwire.comSOURCE: SeaPRwire19/12/2024 Dissemination of a Financial Press Release, transmitted by EQS News.The issuer is solely responsible for the content of this announcement.Media archive at www.todayir.comEQS
Thu, Dec 19
China Overseas Land and Investment Limited’s MSCI ESG Rating Upgraded to “A”
(Hong Kong, 18 December 2024) China Overseas Land and Investment Limited (the “Company” or “COLI”; Stock Code: 0688.HK) is pleased to announce that the international authoritative index institution Morgan Stanley Capital International ("MSCI") has recently published COLI’s latest Environmental, Social, and Governance (“ESG”) rating results. With its outstanding performance in sustainable development, COLI’s MSCI ESG Rating has been upgraded from "BBB" to "A", an industry-leading grade.MSCI ESG Ratings is one of the most renowned ESG evaluation systems worldwide. Its rating results are widely recognized by global investment institutions and extensively applied in their investment decisions. The upgrade of COLI's ESG rating from "BBB" in 2022 to "A" in the current evaluation not only reflects the company's strides in ESG management but also represents the affirmation and recognition of the company's ESG management capabilities and long-term investment value by the global capital market. Photo source from https://www.msci.com/our-solutions/esg-investing/esg-ratings-climate-search-tool/issuer/china-overseas-land-investment-ltd/IID000000002161849 “Good Products, Good Services, Good Effectiveness and Good Citizen” is the business philosophy that COLI has been insisting on for more than 40 years, which is also the company’s unwavering commitment to sustainable development. COLI consistently aligns itself with world-class leading enterprises, publishing high-quality sustainability reports meeting international standards for 12 consecutive years, in response to the core indicators of prominent ESG rating bodies. COLI's proactive engagement in green building initiatives, innovative R&D, robust corporate governance, compliance and risk management, sustainable supply chain practices, talent cultivation, and community welfare projects underscores its distinctive qualities and achievements. These endeavors have garnered significant acclaim from governmental bodies and both local and international professional rating agencies.– End –China Overseas Land & Investment Ltd.China Overseas Land and Investment Limited (“COLI”; Stock Code: 0688.HK) was listed on the Stock Exchange of Hong Kong Limited in August 1992. It was the first Chinese enterprise to directly go public by using the assets of its business in Hong Kong. The Company became a constituent stock of the Hang Seng Index. The Company’s core businesses consist of the development and sales of property projects and the operation of commercial assets, with business spans across Hong Kong, Macau, London and mainland China. The Company has successfully invested in and developed numerous popular and exquisite properties which were well received by the market. The Company’s vision is “to be an exceptional global property development corporation”, and upholds pragmatism and integrity as its philosophy in going forward in a steady manner.For further information, please contact:Corporate Communications DepartmentChina Overseas Land & Investment Ltd.Tel: (852) 2988 0666 | Fax: (852) 2865 7517 | E-mail: coli.pr@cohl.com | Website: www.coli.com.hk19/12/2024 Dissemination of a Financial Press Release, transmitted by EQS News.The issuer is solely responsible for the content of this announcement.Media archive at www.todayir.comEQS
Thu, Dec 19
Baird raises Tesla price target by $200 on strong 2025 outlook
Investing.com -- Baird raised its price target for Tesla Inc (NASDAQ:TSLA) to $480 from $280, on strong growth prospects in the automaker, supported by cost reductions, new models, and favourable regulatory dynamics.Investing.com
Thu, Dec 19
Walt Disney top pick at Morgan Stanley, experiences segment to drive growth
Investing.com -- Morgan Stanley said Walt Disney Company (NYSE:DIS) was its top pick, as it expects theme parks and cruise business to drive growth in the coming years, supported by scaled investments and improving margins.
Investing.com
Thu, Dec 19
Evercore sees upside for Target, Best Buy on holiday shopping trends
Investing.com -- Evercore ISI initiated positive tactical calls on Target Corporation (NYSE:TGT) and Best Buy Co Inc (NYSE:BBY) on improved holiday shopping trends and favourable spending intentions in key categories.Investing.com
Thu, Dec 19
