** U.S.-listed shares of uniQure UQ1.F, QURE.O more than triple to a near five-year high of $47.37
** Stock set for its best day ever, if gains hold
** The Netherlands-based drugmaker says its experimental gene therapy significantly slowed progression of a brain disorder in early-to-mid stage study
** QURE is developing a therapy called AMT-130 to treat Huntington's disease, a rare inherited brain disorder that progressively impairs movement, thinking, and behavior, ultimately leading to severe disability and death
** Separately, QURE says it secured a $175 million loan from Hercules Capital HTGC.N to support the potential U.S. launch of AMT-130
** Including session's move, stock up 162.1% YTD