U.S. STOCKS ON THE MOVE-Vaccine makers, NextDecade, Alaska Air Group

The S&P 500 and the Nasdaq hit record highs on Friday in mixed trading, while Wall Street's main indexes remained on track to log gains in a week of economic reports that solidified expectations for interest rate cuts..N

At 13:29 EDT, the Dow Jones Industrial Average .DJI was down 0.35% at 45,946.04.The S&P 500 .SPX was up 0.05% at 6,591.00, and the Nasdaq Composite .IXIC was up 0.45% at 22,141.59. The top three S&P 500 .PG.INX percentage gainers: ** Warner Bros Discovery Inc WBD.OQ, up 17.5% ** Tesla Inc TSLA.OQ, up 6.7% ** Paramount Skydance Corp PSKY.OQ, up 4.1%

The top three S&P 500 .PL.INX percentage losers: ** Arista Networks Inc ANET.N, down 7.1% ** Moderna Inc MRNA.OQ, down 7.1% ** Oracle Corp ORCL.N, down 4.6% The top three NYSE .PG.N percentage gainers: ** BGSF Inc BGSF.N, up 21.7% ** IONQ Inc IONQ.N, up 17.1% ** Sunlands Technology Group STG.N, up 11.6%

The top three NYSE .PL.N percentage losers: ** Studio City International Holdings Ltd MSC.N, down 16.7% ** Offerpad Solutions Inc OPAD.N, down 13.2% ** Vince Holding Corp VNCE.N, down 12.7% The top three Nasdaq .PG.O percentage gainers: ** GlucoTrack Inc GCTK.OQ, up 137.2% ** iSpecimen Inc ISPC.OQ, up 84.1% ** Office Properties Income Trust OPI.OQ, up 79.9%

The top three Nasdaq .PL.O percentage losers: ** Next Technology Holding Inc NXTT.OQ, down 54.8% ** Alset Inc AEI.OQ, down 39.5% ** VCI Global Ltd VCIG.OQ, down 31.8%

** Adobe ADBE.O:

BUZZ - Shares gain after raising annual revenue, profit forecasts nL3N3UZ0HR

** Super Micro ComputerSMCI.O :

BUZZ - Shares rise after starting shipments of Nvidia systems nL3N3UZ0L0

** RHRH.N :

BUZZ - Shares fall after tariff-driven annual forecast cuts nL6N3UZ0HF

** GE VernovaGEV.N :

BUZZ - Jefferies raises GE Vernova PT on stronger valuations compared to peers nL3N3UZ0NM

** CleanCore ZONE.A :

BUZZ - Small-cap firm CleanCore climbs after hoarding 500 million dogecoins nL3N3UZ0OS

** Apimeds Pharma APUS.A :

BUZZ - Shares jump as FDA backs faster approval path for non-opioid pain drugs nL3N3UZ0QD

** Lennox LII.N :

** Trane Technologies2IS.F :

BUZZ - Jefferies trims Lennox, Trane PT over softer residential HVAC demand nL3N3UZ0RM

** Avidity BiosciencesRNA.O :

BUZZ - Shares rise after boosted $600 mln equity raise nL6N3UZ0L9

** CamtekCAMT.TA :

BUZZ - Shares fall after $425 mln convertible bonds sale nL6N3UZ0KW

** Hoth TherapeuticsHOTH.O :

BUZZ - Shares climb on $1 mln crypto reserve plan nL3N3UZ0TW

** J.M. Smucker SJM.N :

BUZZ - Shares slip after Argus downgrades to 'hold' nL6N3UZ0MA

** Array TechnologiesARRY.O :

BUZZ - Shares fall as BofA downgrades rating to 'underperform' nL3N3UZ0SX

** Anebulo Pharmaceuticals ANEB.O :

BUZZ - Shares rise as it weighs going-private deal after getting fresh options nL6N3UZ0NC

** Prenetics Global PRE.O :

BUZZ - DNA test provider Prenetics jumps after lifting annual forecast nL3N3UZ0V6

** Cocrystal PharmaCOCP.O :

BUZZ - Shares soars on oral norovirus drug progress nL3N3UZ0WZ

** Warner Bros DiscoveryWBD.O :

** Paramount SkydancePSKY.O :

BUZZ - Warner Bros, Paramount Skydance extend gains to second day after acquisition report nL3N3UZ0Z1

** Alaska Air Group ALK.N :

BUZZ - Shares rise after UBS lifts rating on profit growth potential nL3N3UZ0PZ

** NextDecade NEXT.O :

BUZZ - Shares fall after Morgan Stanley cuts rating, price target nL3N3UZ0ZT

** BioNTech22UAy.DE, BNTX.O:

** Moderna MRNA.O:

** Pfizer PFE.N:

BUZZ - Vaccine makers down after report Trump officials to link child deaths to COVID shots nL3N3UZ139

A summary of S&P 500 sector performance at 01:25 p.m. EDT