
Brokerage TD Cowen downgrades drugmaker Merck's MRK.N shares to "hold" from "buy" on weak forecast and a "lack of clarity" regarding shipment of its HPV vaccine Gardasil in China
Last week, MRK forecast total revenues below Wall Street estimates and said it would not ship Gardasil in China until at least the middle of the year
Lowers PT to $100 from $121 on reduced profit and sales estimates for each year through 2030
Brokerage says MRK's business development effort seems to have lost momentum ahead of blockbuster cancer therapy Keytruda losing key patents in 2028
Beyond Keytruda, MRK's growth story "has not improved convincingly" despite a promising pipeline of experimental treatments, brokerage says
MRK's price to earnings ratio (P/E), a common benchmark for valuing stocks, will trough in 2026 - two years before Keytruda loses exclusivity, TD Cowen says
Stock has fallen 24% since late July when it first disclosed Gardasil troubles