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Uni-Bio Science Group and Kexing Biopharm Forge Strategic Partnership to Accelerate Global Expansion of Osteoporosis Treatment Bogutai®

Zhangqiu District, Jinan City, Shandong Province – September 2025Uni-Bio Science Group (“the Group”) is pleased to announce the signing of a strategic cooperation agreement with Kexing Biopharm (Stock Code: 688136.SH), a leading biopharmaceutical company with extensive expertise in global commercialization. Under this landmark agreement, Beijing Genetech Pharmaceutical Co., Ltd. (“Beijing Genetech”), a subsidiary of the Group, has granted Kexing Biopharm exclusive rights to commercialize Bogutai® (Teriparatide Injection) in six international markets, including Saudi Arabia, Egypt, Morocco, Colombia, Argentina, and Mexico (“Cooperation Regions”). Bogutai® is expected to complete registration and generate revenue in the Cooperation Regions as early as the end of 2026. The signing ceremony, held in Zhangqiu District, Jinan City, marks a pivotal step in the Group’s international expansion and its commitment to advancing osteoporosis care worldwide.Pioneering Osteoporosis Treatment with Proven ResultsBogutai® is a recombinant human parathyroid hormone analog (PTH1–34), an anabolic treatment for osteoporosis that has been widely recognized for its efficacy and safety. Recommended by numerous domestic and international clinical guidelines, Teriparatide is particularly effective in improving bone microarchitecture and reducing fracture risk in postmenopausal women at high risk of fractures. Since its launch in China in March 2024, Bogutai® has demonstrated rapid market adoption, achieving a remarkable revenue growth of 248.9% year-on-year in the first half of 2025, reaching approximately HK$65.6 million. This impressive performance underscores the strong demand for innovative osteoporosis therapies and highlights the untapped potential of Bogutai® in global markets. Addressing the Global Osteoporosis EpidemicOsteoporosis, often referred to as a “silent killer,” affects over 200 million people globally, with the aging population exacerbating its prevalence. Early-stage osteoporosis is typically asymptomatic, leading to delayed diagnoses and severe complications such as fractures. In China, for example, only 6.5% of individuals receive osteoporosis treatment within six months of a fracture. Similarly, emerging markets across the Middle East and North Africa face low diagnosis and treatment rates despite growing awareness and significant patient populations. Injectable therapies like Teriparatide have been recommended by the Guidelines for Rational Drug Use of Osteoporosis in Primary Care (2021) for patients unable to tolerate oral medications, those with poor adherence, or individuals at high risk of fractures, including elderly patients with multiple vertebral or hip fractures. With its targeted mechanism of action as a bone-forming agent, Bogutai® is uniquely positioned to address this unmet medical need in both established and emerging markets. It is estimated that the osteoporosis market in the Cooperation Regions is nearly USD 1.5 billion, with a patient population exceeding 10 million. A Collaboration Built on Complementary Strengths Commenting on the partnership, Mr. Kingsley Leung, Chairman of Uni-Bio Science Group, said: “Teriparatide Injection is a transformative therapy with immense potential in overseas markets. By partnering with Kexing Biopharm, a company with a robust international commercialization network and proven operational expertise, we are confident in our ability to bring Bogutai® to patients in need across key regions. This collaboration represents a critical step in our mission to improve global bone health.”Mr. Zhao Yanqing, General Manager of Kexing Biopharm, added: “We are excited to join forces with Uni-Bio Science Group to unlock the regional potential of Bogutai®. With our established capabilities in regulatory approvals and market promotion, we aim to accelerate product registration and commercialization, ensuring that this innovative therapy reaches patients quickly and effectively.”Enhancing Global Competitiveness in Osteoporosis CareWith over 20 years of international commercialization experience, Kexing Biopharm has built a strong marketing network spanning the European Union and emerging markets. The addition of Bogutai® to its portfolio complements its existing success with previously introduced denosumab injection, creating a comprehensive suite of osteoporosis treatments that combines “anti-resorptive” and “bone-forming” therapies. This synergy enhances the competitiveness of both companies in addressing the growing global demand for osteoporosis care. For Uni-Bio Science Group, this partnership is a key milestone in its internationalization strategy. Bogutai® is expected to generate revenue in the Cooperation Regions as early as the end of 2026, and with its competitive pricing, it may achieve higher profit margins. Beyond the collaboration with Kexing Biopharm, the Group is actively pursuing FDA approval for Bogutai® in the United States, having already received a waiver for in vivo bioequivalence studies. With this expedited regulatory pathway, FDA approval is anticipated in 2027, further solidifying the Group’s position as a leader in osteoporosis treatment. The Group is also advancing innovative pipeline products, including Uni-PTH (microneedle) for osteoporosis and UB107 (a Class III medical device) for bone repair, reinforcing its commitment to addressing unmet medical needs in bone metabolism and regenerative medicine. Shaping the Future of Osteoporosis TreatmentLooking ahead, Uni-Bio Science Group remains dedicated to expanding its global footprint, deepening strategic partnerships, and accelerating the development of innovative therapies. By bringing Chinese innovation to the world, the Group aims to improve the lives of osteoporosis patients and set new standards in bone health and regenerative medicine. EndAbout Bogutai® (Teriparatide Injection)Bogutai® (Teriparatide Injection) is a biologically expressed recombinant human parathyroid hormone analog (PTH1–34), representing the active 34-amino-acid N-terminal region of the full 84-amino-acid human parathyroid hormone. This advanced therapeutic agent is specifically indicated for postmenopausal women with osteoporosis who are at high risk of fractures.Bogutai® exerts its effects by stimulating osteoblast activity, promoting new bone formation, and increasing bone mineral density (BMD). Unlike antiresorptive therapies that primarily inhibit bone resorption, Bogutai® actively enhances bone remodeling by increasing osteoblast-mediated bone deposition while indirectly regulating osteoclast activity to maintain a balanced bone turnover. This anabolic mechanism makes it a highly effective treatment option for reducing the risk of fractures and improving skeletal integrity in patients with severe osteoporosis.About Uni-Bio Science GroupUni-Bio Science Group Limited (Stock Code: HK 00690) is a biopharmaceutical company dedicated to utilizing new synthetic biology technology to develop next generation regenerative therapies in the orthopedics, ophthalmology, dermatology and medical aesthetics. The Group also has three GMP manufacturing bases in Beijing, Dongguan and Shenzhen. From R&D, production, manufacturing, to sales and distribution of biopharmaceutical and high value chemical drugs and medical-class skincare raw material products, the Group has established a fully integrated business platform serving the entire value chain.About Kexing BiopharmKexing Biopharm (Stock Code: 688136.SH) is a leading multinational biopharmaceutical company. It has established 6 overseas subsidiaries and offices, which have acquired market access and achieved sales in dozens of countries and regions such as the European Union, Brazil, Philippines and Indonesia.12/09/2025 Dissemination of a Financial Press Release, transmitted by EQS News.The issuer is solely responsible for the content of this announcement.Media archive at www.todayir.com
EQS
Sep 12, 2025

Modern Dental Group Signed MoU with Sindan on Developing the First World-class Dental Lab in the UAE by Leveraging Advanced Technology

The MoU signing between Modern Dental Group and Sindan, witnessed by Mr. Nicholas Ho, the Commissioner for Belt and Road.(Hong Kong, 12 September 2025) - Modern Dental Group Limited (“Modern Dental” or “the Group”, stock code: 03600.HK), a leading global dental prosthetic devices provider, was invited to attend the 10th “Belt and Road Summit” co-organized by the Hong Kong Special Administrative Region (HKSAR) Government and the Hong Kong Trade Development Council. The Group has signed a Memorandum of Understanding (MoU) with Sindan, a leading technology manufacturing hub in the United Arab Emirates (UAE) at the Cooperation Agreement Signing Ceremony on 10 September. We will jointly develop the first world-class dental laboratory in the UAE by leveraging advanced manufacturing technologies and dental expertise, accelerating the Group’s swift entry and expansion in the rapidly evolving Middle East and North Africa (MENA) market.Modern Dental Group has been committed to advancing its global dental footprint and has actively facilitated the digital transformation in dentistry to support practitioners worldwide by upgrading treatment plans to provide patients with a more precise and superior comprehensive treatment experience. Sindan, the leading technology manufacturing company in the UAE, specializes in developing innovative technologies for industrial design, production, and deployment of mission-critical components, providing manufacturing solutions across energy, mobility, consumer products, aerospace, and healthcare sectors. This partnership between Modern Dental Group and Sindan has fully demonstrated a mutual high regard for their respective capabilities and expertise in the sector.Modern Dental Group owns a unique global dental distribution network that enables new dental products and solutions to quickly penetrate emerging markets. Through this collaboration, the Group leverages its extensive expertise accumulated over the past decades to establish a strong presence and facilitate rapid access in the dynamic MENA landscape. Our competitive advantage and leading position in the dental supply chain have made us the first global dental hub to cooperate with leading technology pioneer and establish a dental technology collaboration in the UAE, driving new momentum for innovation in the dental field.It is foreseeable that the Group will continue to strengthen its influential position in the industry and attract even greater international capital support in the future, further promoting technological innovation and consolidating the global dental market. Looking ahead, the Group remains committed to its core values of innovation-driven development and win-win cooperation, fully leveraging the established comprehensive dental hub in capturing growing opportunities ahead. We are committed and strategically positioned to partner with global collaborators in delivering innovative and diverse dental solutions, creating a new landscape for international cooperation in the dental field and driving business growth.About Modern Dental Group Modern Dental Group Limited (Stock code: 03600.HK) is a leading global dental prosthetics provider, distributor and consultant with a focus on providing custom-made prostheses to customers in the growing prosthetics industry. Our product portfolio is broadly categorized into three product lines: fixed prosthetic devices, such as crowns and bridges; removable prosthetic devices, such as removable dentures; and other devices, such as orthodontic devices, sports guards, clear aligners, and anti-snoring devices.Modern Dental Group has a global portfolio of respected brands, including Labocast, Permadental and Elysee Dental in Western Europe, YZJ Dental in China, Modern Dental Lab in Hong Kong, Modern Dental USA and MicroDental in the United States, Modern Dental Pacific in Australia and New Zealand, Modern Dental SG in Singapore, Modern Dental TW in Taiwan, Apex Digital Dental in Malaysia and Hexa Ceram in Thailand. We have grown these brands by providing premium and consistent quality products and superior customer service. We have more than 80 service centers in over 28 countries and serve over 35,000 customers.12/09/2025 Dissemination of a Financial Press Release, transmitted by EQS News.The issuer is solely responsible for the content of this announcement.Media archive at www.todayir.com
EQS
Sep 12, 2025
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