Emergent BioSolutions (EBS) 2026财年第三季度业绩电话会:更新业绩指引与更高利润率展望
Emergent BioSolutions公布2026年第三季度营收1.1亿美元,低于去年同期的2.31亿美元,主要受医疗反制措施交付时机变动影响。公司前三季度营收达5亿美元,调整后EBITDA为1.28亿美元,经营活动现金流1.22亿美元。期末现金及流动资金分别为1.76亿和2.26亿美元,总债务降至5.14亿美元。管理层上调全年调整后毛利率指引至45%至47%,预计全年营收6.00亿至6.45亿美元,调整后EBITDA为1.10亿至1.40亿美元。业务重点包括推进MCM国际交付、NARCAN纳洛酮市场布局及坎顿制造设施重启。
Emergent BioSolutions(纽交所代码:EBS)公布2026年第三季度营收为1.1亿美元,低于去年同期的2.31亿美元,主因医疗反制措施(MCM)交付时间的变动使部分收入转移至其他期间。公司更新了全年营收及调整后EBITDA预期,同时上调了调整后毛利率指引。
核心要点
- 2026年第三季度营收为1.1亿美元,处于公司此前指引范围内,而2025年第三季度为2.31亿美元。
- 调整后EBITDA为负500万美元,调整后毛利率为28%,反映了收入确认时点、产品组合以及商业部门面临的竞争压力。
- 今年迄今营收达5亿美元,调整后EBITDA为1.28亿美元(利润率为25%),经营活动现金流为1.22亿美元。
- 在回购了7500万美元的债券本金后,Emergent在该季度末拥有1.76亿美元现金、2.26亿美元流动资金以及5.14亿美元的总债务。
- 管理层目前预计2026全年营收为6.00亿美元至6.45亿美元,调整后EBITDA为1.10亿美元至1.40亿美元。
- 调整后毛利率指引上调至45%–47%,较公司今年8月的指引提高了300个基点。
核心财务数据
| 指标 | 2026年第三季度 / 2026年迄今 | 比较或背景说明 |
|---|---|---|
| 三季度营收 | 1.1亿美元 | 2025年第三季度为2.31亿美元;下滑主要反映了MCM交付时机的影响 |
| 三季度调整后EBITDA | 负500万美元 | 受收入确认时点、产品组合及商业部门竞争影响 |
| 三季度调整后毛利率 | 28% | 受当季产品组合影响 |
| 三季度SG&A及研发费用 | 5600万美元 | 包含800万美元重组费用;2025年第三季度为5200万美元 |
| 今年迄今营收 | 5亿美元 | 符合管理层预期 |
| 今年迄今调整后EBITDA | 1.28亿美元 | 25%利润率 |
| 今年迄今调整后毛利率 | 49% | 反映了运营效率与产品组合情况 |
| 今年迄今经营活动现金流 | 1.22亿美元 | 从调整后EBITDA转化情况良好 |
| 现金 | 1.76亿美元 | 截至2026年9月30日 |
| 总流动资金 | 2.26亿美元 | 截至本季度末 |
| 总债务 | 5.14亿美元 | 低于去年同期的6.93亿美元 |
| 净债务 | 3.39亿美元 | 低于去年同期的4.48亿美元 |
| 净杠杆率 | 2.4倍 | 基于过去12个月调整后EBITDA计算 |
业务与运营表现
第三季度医疗反制措施营收为5900万美元。业绩包括一项2400万美元的CYFENDUS合同变更,当季已向美国政府完成交付。Emergent还完成了与2026年3月合同变更相关的绝大部分TEMBEXA片剂交付。
公司表示已签署全部预期的6项美国政府合同变更。国际业务方面,Emergent在第三季度跨13个国家完成了19笔销售。今年迄今,国际销售及产品订单贡献了7200万美元,占MCM营收的22%。
随着纳洛酮市场面临价格和销量的双重压力,商业部门营收有所下滑。管理层表示,价格与2026年第二季度相比相对稳定,且NARCAN维持了其在美国市场的领先地位。在加拿大政府一项新的多年长期采购意向支持下,加拿大纳洛酮销售表现依然强劲。
Emergent继续推广4毫克NARCAN鼻喷剂和8毫克KLOXXADO鼻喷剂。管理层表示,随着阿片类药物效力日益增强,急救人员可能需要更高剂量的纳洛酮,这两款产品为此提供了不同的选择。
公司8月份进行的重组预计每年可节省约4000万美元的年化成本,初步成效将在2026年第四季度显现。扣除800万美元的重组费用后,第三季度SG&A及研发费用同比有所下降。
Emergent还表示,坎顿制造设施的重启工作正按计划推进。其增长重点包括广谱埃博拉治疗项目、潜在的广谱流感疫苗机会,以及涉及TEMBEXA、Ebanga和Raxibacumab的相关工作。
管理层业绩指引
| 2026全年指引 | 最新展望 | 管理层点评 |
|---|---|---|
| 总营收 | 6.00亿美元–6.45亿美元 | 反映了当前对MCM与商业部门的预期 |
| 调整后毛利率 | 45%–47% | 较8月指引上调300个基点 |
| 调整后EBITDA | 1.10亿美元–1.40亿美元 | 更新主要反映了营收展望的变化 |
| 商业部门营收 | 较2025年下降20%–25% | 目前趋向于降幅范围的低端 |
受剩余国际交付与美国政府采购进度的影响,管理层预计全年MCM营收将低于2025年。部分交付可能会推迟至第四季度之后,并延至2027年初。
毛利率展望的上调反映了制造环节的改进、产品组合优化以及NARCAN在美国公共利益渠道价格的稳定。管理层还计划继续严格控制运营费用。
风险与关注领域
- MCM营收对美国政府采购及国际交付的时间节点依然敏感,相关交付可能会在不同季度或财年之间波动。
- 纳洛酮营收继续面临价格和销量的竞争压力,尤其是在美国公共利益渠道。
- 2026年早些时候,新的纳洛酮竞争产品获得批准。管理层表示,这些产品尚未对市场产生重大影响,但公司正持续密切关注。
- 全年营收区间的达成在一定程度上取决于某些美国及国际MCM订单是在2026年底还是2027年初落地。
- 管理层强调,演变中的生物威胁以及可能滥用人工智能制造新型病原体等因素,进一步提升了生物国防准备工作的重要性。
分析师问答环节亮点
针对纳洛酮需求,管理层表示,阿片类药物过量致死仍是推动更广泛获取NARCAN的主要驱动因素。管理层还指出,两党政府支持以及阿片类药物相关诉讼和解资金,将成为未来十年持续资金支持的潜在来源。
关于天花防范,管理层将ACAM2000描述为政府储备的重要单剂量疫苗。Emergent将ACAM2000与TEMBEXA联合定位,可同时提供疫苗和治疗方案。
当被问及MCM订单延迟问题时,管理层表示,得益于与美国、加拿大及其他政府客户的定期沟通,可见度依然相当良好。不过,某些订单的具体交付时间仍存在不确定性,这可能会决定营收最终落在2026年指引区间的上限还是下限。
业绩电话会议完整文字实录
完整财报电话会议逐字稿
管理层陈述
Operator
Hello, everyone. Thank you for joining us, and welcome to the Emergent BioSolutions Third Quarter 2026 Earnings Call. [Operator Instructions] I will now hand the conference over to Frank Vargo, VP and Treasurer. Frank, please go ahead.
Frank Vargo
Good afternoon, everyone, and thank you for joining us as Emergent discusses its operational and financial results for the third quarter of 2026. As is customary, today's call is open to all participants, is being recorded and is copyrighted by Emergent BioSolutions.
In addition to today's press release, a slide presentation accompanying this webcast is available to all webcast participants.
Turning to Slide 2. During today's call, Emergent may make projections and other forward-looking statements related to business, future events, prospects or future performance. These forward-looking statements are based on our current intentions, beliefs and expectations regarding future events.
Any forward-looking statements speak only as of the date of this conference call, and except as required by law, Emergent does not undertake to update any forward-looking statements to reflect new information, events or circumstances. Investors should consider this cautionary statement as well as the risk factors identified in Emergent's periodic reports filed with the SEC when evaluating these forward-looking statements.
During today's call, Emergent may also discuss certain non-GAAP financial measures that include adjustments to GAAP figures to provide additional transparency regarding the company's operating performance. Please refer to the tables included in today's press release.
Turning to Slide 3. The agenda for today's call includes remarks from Joe Papa, President and Chief Executive Officer, who will provide an update on the company's transformation plan, business performance and key highlights. Rich Lindahl, EVP and Chief Financial Officer, will then review the third quarter 2026 financial results and provide an update on full year 2026 guidance.
Joe Papa will conclude with a discussion of the company's key catalysts for growth, followed by a question-and-answer session. Finally, for the benefit of those who may be listening to the replay of this webcast, this call is held and recorded on November 2, 2026. Since that time, Emergent may have made announcements related to topics discussed during today's call.
With that, I will now turn the call over to Joe Papa. Joe?
Joseph Papa
Hello, everyone, and thank you for joining us to discuss Emergent's third quarter 2026 financial results. This is Joe Papa, President and Chief Executive Officer of Emergent. And I'm joined today by Rich Lindahl, our Chief Financial Officer. This afternoon, I will share an update on our multiyear transformation plan, the actions we implemented during the quarter to strengthen the business and the progress we are making across our diversified medical countermeasure and naloxone portfolios.
Rich will then review our third quarter financial results and our outlook for the remainder of 2026. I will close with the growth catalysts and priorities that will guide us as we finish the year. Then we'll open up the call for Q&A.
Before we begin, though, I want to acknowledge an important milestone. This November marks 20 years since Emergent's initial public offering in November 2006. As we reflect on that anniversary, our mission to protect and save lives remains our foundation. We are focused on building upon that legacy as we advance our transformation and position Emergent for the future.
I'd also like to take a moment to recognize Rich. After 17 years as a public company CFO, of which approximately 9 years were spent at Emergent, Rich has decided to retire effective December 31, 2026. Frank Vargo, our Vice President and Treasurer, will assume the role of Interim CFO on January 1, 2027. To support a seamless transition, Rich will continue to serve as a Senior Executive Adviser through March 31, 2027.
Rich has been a trusted partner to me, our Board and our leadership team. He has helped guide Emergent through periods of significant change, strengthen our financial discipline and played an important role in the progress we have made to position the company for the future.
He's also built a very strong and highly talented finance and IT organization. We are fortunate to have an experienced leader as Frank, who knows our business, understands our priorities and will provide continuity and disciplined financial stewardship during this transition.
On behalf of the Board and our colleagues, I want to thank Rich for his leadership, his commitment to Emergent's mission and his dedication to our people. I'll now begin the presentation on Slide 4. For more than 25 years, Emergent has prepared for and responded to complex public health threats. Our mission remains clear: to protect and save lives. That mission is especially important in a world where biological threats are evolving, geopolitical uncertainty is elevated and advances in technology, including artificial intelligence can create both new opportunities and new risks.
We continue to believe that Emergent is the leader in biodefense preparedness and naloxone serving patients, customers and government partners around the world.
Turning to Slide 6. Against that backdrop, our multiyear transformation plan continues to guide our business and strategic decisions. We are focused on improving operating performance, aligning our cost structure, strengthening the balance sheet, advancing growth opportunities where Emergent has differentiated capabilities and maintaining a strong commitment to patient safety, quality and compliance.
Let's move to Slide 8. After an exceptional better-than-expected second quarter performance of $234 million in revenue, our third quarter results were consistent with expectations with $110 million in revenue within our guidance range. This brings our year-to-date revenue to $500 million.
Additional highlights from the quarter include our overall profitability and cash generation support investment in growth. Year-to-date, adjusted EBITDA reached $128 million, a 25% margin with $122 million in operating cash flow. Cash stood at $176 million with $226 million in liquidity.
Financial discipline remains a priority for us. We repurchased $75 million in bond principal and continued cost prioritization is occurring. Our MCM business delivered solid performance. We executed a $24 million contract modification for CYFENDUS, made deliveries to the U.S. government by the close of quarter 3.
We also completed a TEMBEXA tablet delivery from a contract modification awarded in March of this year. Internationally, we completed product sales to more than 13 countries in the third quarter, which demonstrates the diversification of our MCM business and the importance of biodefense preparedness internationally around the world.
Naloxone remains central to community preparedness to maintain our U.S. market-leading position, while we continue to be competitive in the market to ensure customers have access to both NARCAN Nasal Spray and KLOXXADO Nasal Spray when needed.
Our growth initiatives are progressing. Importantly, we are taking a disciplined approach when it comes to the evaluation and pursuit of certain business development opportunities. The Canton manufacturing facility restart milestones remain on track, and we are proud to celebrate this restart with the local Commonwealth officials.
Finally, we are progressing the pan-Ebola therapy program and AI partnerships for clinical development work. We have a handful of other AI and machine learning platforms that we are engaging for pipeline and growth opportunities.
We plan to advance this critical work while remaining focused on patient safety, quality and compliance.
Turning to Slide 9. I'd like to highlight the recent reports on the rising threat of AI and bio terrorism, national security and the role Emergent can play in collaboration with other companies on potentially addressing such risk. In August, we issued a call to cross-collaborate with AI leaders including Anthropic and OpenAI on key areas like threat detection and to develop a preparedness framework. We expect to continue these efforts and be a potential partner on AI bioterrorism, AI bioterrorism prevention efforts today and into the future.
On Slide 10, let's take a look at our MCM results. Through the great efforts of our MCM team, we secured $59 million in revenue in the third quarter, which was driven by an executed $24 million CYFENDUS contract modification. The product was delivered to the U.S. government within the quarter, while the team also completed the majority of the TEMBEXA tablet delivery from a March 2026 contract modification with the U.S. government.
To date, we executed all 6 anticipated U.S. government contract modifications. On the international side, we supplied a diverse mix of MCM to 13 different countries and closed 19 sales during the quarter. International sales and product orders contributed $72 million of revenue, representing 22% of year-to-date MCM revenue.
Preparedness very important across the U.S. and Canada. Our focus remains increasing on access to overdose reversal medications with over-the-counter NARCAN continuing the standard of care and KLOXXADO 8-milligram offering another important option. In the U.S., we continue supporting states, law enforcement and harm reduction organizations as well as retail partners and workplaces on increasing access and the availability for vulnerable populations.
We continue seeing strong growth of NARCAN across Canada. And the government of Canada recently executed standing offer, which creates a multiyear pathway for NARCAN. To this end, we're complementing access with public awareness through our Ready to Rescue campaign and college educational engagement.
These are important efforts to help increase access, awareness and the availability of NARCAN and KLOXXADO to save lives. Let me now hand the call over to Rich. Following Rich's comments, I'll spend some time elaborating on our business outlook and growth catalysts. Rich?
Richard Lindahl
Thank you, Joe. Good afternoon, everyone, and thank you for joining us today. Our third quarter results reflect continued execution against our transformation priorities. Revenue was within our guidance range. We maintained disciplined control of operating expenses, and we continue to generate strong cash flow while taking decisive actions to align our cost structure with current business realities.
In August, we implemented restructuring actions across the organization to improve efficiency and better align resources with our strategic priorities. We continue to expect these actions to generate approximately $40 million of annualized savings, the initial impact becoming evident in the fourth quarter of 2026. We also continued to strengthen the balance sheet. During the quarter, we repurchased $75 million aggregate principal amount of our unsecured bonds for $68 million of cash.
Together with the April term loan refinancing and strong operating cash generation, this action further reduced gross debt while net leverage remained stable.
Turning to Slide 13. Third quarter revenue was $110 million, within our prior guidance range compared with $231 million in the third quarter of 2025. The year-over-year comparison was primarily influenced by the timing of MCM deliveries. As a reminder, our strong second quarter 2026 results reflected accelerated deliveries, which now skews the third quarter's comparison to the prior year.
At the same time, this factor also drove robust receivable collections and cash flow from operations in the third quarter of 2026. Adjusted EBITDA was negative $5 million, and adjusted gross margin was 28%. Our profitability in the quarter was influenced by the timing of revenue, product mix and the competitive market dynamics in the Commercial segment. SG&A and R&D operating expenses were $56 million, including $8 million of restructuring costs compared with $52 million in the third quarter of 2025.
Excluding those restructuring costs, SG&A and R&D operating expenses were lower year-over-year, demonstrating effective cost management. Moving to Slide 14. MCM revenue declined year-over-year, primarily due to the timing of U.S. government product deliveries.
Commercial revenue also declined as the naloxone market is experiencing competitive pricing and volume pressure. The performance of naloxone was consistent with our prior outlook and pricing compared to Q2 2026 was relatively stable. Bioservices and contracts and grants revenue remained a smaller component of the overall mix.
Turning to Slide 15. Year-to-date revenue was $500 million, in line with our expectations. Adjusted EBITDA was $128 million, representing a 25% margin. Adjusted gross margin was 49%, reflecting our continued focus on operating efficiency even in light of product mix. Year-to-date operating expenses were $167 million, including $8 million of restructuring costs compared with $176 million in the prior year period.
Moving to Slide 16. The year-to-date revenue comparison reflects the impact of the large onetime international MCM order in 2025. Commercial revenue trends incorporate reduced naloxone pricing and volume in the U.S. public interest channel, partially offset by strength in our Canadian naloxone business.
Overall, portfolio continues to benefit from our strong ongoing collaborative engagement with U.S. and international government customers and from our established market-leading position in naloxone.
On Slide 17, we highlight our rigorous balance sheet management. We ended the quarter with $176 million of cash and $226 million of total liquidity.
Year-to-date operating cash flow was $122 million as our focus on working capital management produced very strong conversion from year-to-date adjusted EBITDA of $128 million. Following our $75 million bond repurchase, gross debt was $514 million at September 30, 2026, compared with $693 million a year ago.
Net debt was $339 million compared with $448 million, and net leverage remained stable at 2.4x trailing 12-month adjusted EBITDA compared with 1.9x a year ago.
Transitioning to Slide 18, the progress on our balance sheet is even more evident when viewed over the course of the turnaround. Through the third quarter of 2026, we generated $352 million of cumulative operating cash flow.
Gross debt declined by $354 million or 41% from year-end 2023, while net debt has declined by $418 million or 55%, reflecting the net positive impact of our strategic asset divestitures. Over the same period, net leverage decreased from approximately 16x to approximately 2.4x.
Turning to Slide 19. Our capital allocation priorities remain balanced. We continue to support international MCM growth initiatives, invest in internal R&D programs, including the approximately $50 million Ebanga milestone payment made earlier this year and maintain focus on business development opportunities.
At the same time, we refinanced our term loan, repurchased $75 million of unsecured bond principal and repurchased 2 million shares year-to-date for $18.1 million. We ended the quarter with $37.3 million remaining under the share repurchase authorization.
Turning to Slide 20. We're updating our full year 2026 guidance. We now expect total revenues of $600 million to $645 million, reflecting our current outlook for both the MCM and Commercial segments. In our medical countermeasure business, we now expect full year revenues to decline versus the prior year based on the timing of remaining international MCM deliveries and U.S. government procurement as we close out 2026.
Our ongoing dialogue with the U.S. government and allied nations continues to indicate strong demand. However, the timing of certain deliveries may fall outside the fourth quarter.
In our Commercial segment, which is primarily driven by NARCAN, we continue to hold the leading market position. Year-to-date performance is in line with our expectations, though we're currently tracking towards the lower end of our 20% to 25% range of revenue reduction versus 2025.
At the same time, we're raising our adjusted gross margin guidance to a range of 45% to 47%, a 300 basis point improvement versus our August guidance. This reflects our continued focus on operational improvements across our manufacturing network, the impact of product mix and recent stabilization of NARCAN pricing in the U.S. public interest channel.
Finally, we now expect adjusted EBITDA of $110 million to $140 million, with the upper end of the range consistent with the midpoint of our prior guidance. This update primarily reflects our revenue outlook, while we continue to maintain disciplined control of operating expenses as we execute our turnaround.
In summary, third quarter revenue was within our guidance range. Year-to-date adjusted EBITDA was $128 million, and we generated $122 million of operating cash flow through September.
We maintained a strong cash position, stay focused on expense management and took meaningful restructuring actions to improve our cost structure and prepare the business for the future. We also continue to strengthen the balance sheet through proactive debt management.
The repurchase of our unsecured bonds, together with the April refinancing and sustained cash generation, reduced gross debt further while preserving stable net leverage and ample liquidity.
We will continue to allocate capital thoughtfully across debt reduction, targeted investments in growth and shareholder returns while maintaining our commitment to patient safety, quality and compliance.
With that, I'll turn the call back to Joe to discuss our business outlook and growth catalysts before we move to Q&A. Joe?
Joseph Papa
Thank you, Rich. Turning to Slide 22. I'd like to briefly touch on the key catalysts we believe can enable growth in 2026 and beyond. Our growth organization is focused on programs where Emergent has differentiated expertise, clear mission alignment and the potential to create sustainable value.
This includes advancing our pan-Ebola therapeutic program, evaluating a pan-flu vaccine opportunity, progressing work related on TEMBEXA, Ebanga and Raxibacumab and selectively validating external opportunities that fit our capabilities and financial criteria.
Turning to Slide 23. Our near-term pipeline and current asset strategy is focused on maximizing the value of programs where Emergent has a differentiated experience, clear mission alignment and the potential to support sustainable growth. And moving to our summary and close on Slide 24. Our third quarter results reflect continued execution across the business and the delivery of our U.S. government partner order.
As we look at the remainder of 2026, our priorities are clear. First, stay focused on our mission to protect and save lives while prioritizing growth, quality and our people every day. Second, deliver for our government and public health customers by meeting commitments, pursuing additional U.S. and international opportunities and strengthening domestic preparedness capabilities.
Third, effectively compete in naloxone by protecting our leadership position, responding competitively to pricing and procurement dynamics and expanding access through different offerings and configurations. And fourth, advance focused growth programs through our integrated growth organization with clear decision points and disciplined capital allocation.
We have made meaningful progress, but we also recognize there is much work to do ahead of us. We're entering the final month of 2026 with a leaner operating model, a more focused growth agenda, stronger financial discipline and a portfolio that addresses some of the most consequential public health threats facing communities around the world. With that, I look forward to your questions. And operator, could you please open the line for any questions.
Operator
[Operator Instructions] Your first question comes from the line of Ram Selvaraju with H.C. Wainwright.
分析师问答
Raghuram Selvaraju
I was just wondering if you could provide us with some additional granularity regarding the underlying market dynamics in the NARCAN market segment, particularly as this pertains to the current state of the competitive landscape as well as drivers of underlying market demand, particularly with respect to, as I think you alluded to during your prepared remarks, the presence of increasingly potent opioid analogs sort of next generation beyond fentanyl.
And I was also wondering if you could comment on current broad-spectrum international demand for smallpox vaccine products, particularly in light of the recent awards that have been announced for MVA-BN and if you think that this may point to increasing demand overall, both within the U.S. and ex U.S. for your smallpox vaccine product?
Joseph Papa
Okay, thank you for the question. We got quite a bit there, and I'll try to make sure I get all pieces of it. But if I leave any out, please come back to me on it. So basically, the market dynamic on NARCAN, it remains good in the sense that there are still way too many people dying from opioid overdose.
So there's still significant demand opportunity for opioid overdose medications. We've got to bring down that death rate. It's come down a lot, but we believe there's still much more we can do, and we want to make sure we continue to increase access for NARCAN because we believe that's what saves lives.
When you have somebody who overdoses, if NARCAN is available, you can save that life. So we need to just continue to make NARCAN more available, and we're doing everything we can, but that's the biggest issue out there.
Number two, funding. The area of funding continues to be an important issue. It's, we believe, a bipartisan supported opportunity that we see both on the congressional Republican and congressional Democrats. There is support for what people believe NARCAN can do to help save lives, making sure the product is available.
Beyond that, on the funding side, we also know that there's a number of legal class action settlements by big pharma companies that distributed opioids. Those funds are available and will be available over the next 10 years. We think that's going to help on the funding side to continue to make products like NARCAN, therapeutic products available and funded so that patients can get access when they need it.
And of course, because, first and foremost, we made NARCAN over-the-counter in 2023, we think that's a big part of making it more accessible because it's over the counter. So those are the issues we face. We did see during -- earlier in the year, some new competitors get approval in the naloxone space.
But at this time, they have not made a major impact on the market, but we continue to monitor that, and we're keeping a close eye on it. And what's important, as we sit here today, NARCAN still has a market-leading position, and we think that's an important differentiator for us because patients and the family member caregivers all know the NARCAN brand name and also the way that we distribute it to make it more accessible.
So those are the issues that we see in the marketplace on the demand side. As it relates to stronger drugs, there's no doubt about that. It's true, whether it be the fentanyl, the carfentanil, some of the other products that are out there. We want to make sure that, once again, NARCAN is available. And for us, it's just making sure NARCAN is going to work, but at times, you may need a higher, more potent product, and we have KLOXXADO.
We think that's the other avenue that the caregivers, first responders will pursue is having both the 4-milligram Naloxone, NARCAN, which is the gold standard, but also have the 8-milligram KLOXXADO. So we want to continue to make sure both drugs are available whatever the first responders need to help patients with.
The second question was -- I'm sorry, remind me of smallpox, what was your question again? The international side...
Raghuram Selvaraju
Yes, it was related to international demand, especially as when we look at recent orders that have been placed for MVA-BN, what implications this may have for ongoing underlying demand for ACAM2000.
Joseph Papa
So ACAM, we feel once again, it's a gold standard. The predecessor product to ACAM was a product that essentially eradicated smallpox around the world. So ACAM still has a very important position. It's a single-dose requirement. It's been used around the world.
So we think ACAM still is a very important product there. Our expectation is that the countries are going to continue to think about what's needed for their own stockpiles. We've been working very closely with governments around the world as well as the U.S. [indiscernible].
And the good news is that ACAM is an important product to help them be prepared for whatever the issues are. In addition to ACAM, we also do and spend a lot of time on TEMBEXA, a therapeutic so that we have the TEMBEXA along with ACAM as a portfolio of products for both for the vaccine side, but also for the therapeutic side, if indeed needed. Personal opinion is that there's a lot of concern that companies will use AI to create new pathogens.
The bad actors that may use the AI to create new pathogens, something like smallpox would be probably one of the things they think about because of the simplicity that they could potentially work on looking at how they can weaponize smallpox and make smallpox even more concerning for people.
So we want to make sure we're prepared as we think about what could happen in the future and how we work with AI companies to be prepared for whatever the circumstances that the bad actors could come forward with. Thank you for your question.
Operator
Your next question comes from the line of Jessica Fye with JPMorgan.
Unknown Analyst
This is [ Dawn ] for Jess. Can you give more specific visibility into when the MCM orders that slipped out of 3Q are expected to land? Is this 4Q catch-up the 2027 push out? Or is it still unscheduled?
Joseph Papa
Sure. I'm going to start, but Rich, you want to add to it. I think what you're really asking is our visibility for the fourth quarter and what we're expecting for this year and then some parts of it obviously extends to 2027. I think that's what you're asking. I think we've got -- right now, we work very closely with the U.S. government to ensure that we understand their needs.
We have regular ongoing meetings with the government to make sure we understand what their needs are, but also the needs of the Canadian government, other governments around the world. We continue to work very closely with to ensure we understand their needs and expectations.
And we have back and forth to make sure that both sides, whether it's us as a supplier or them as customers, will get what they need to make sure that we work on the needs of the stockpile. But there's very good back and forth in conversations with them. I think we have reasonable good visibility into that.
Yes, sometimes orders do slip from quarter-to-quarter depending on specifics. But for the most part, I think we've got pretty good visibility into the program. And as we said, what's great about the third quarter results is that we shipped to 13 countries in the third quarter, which is another important part of the diversification that we've been striving for to ensure that we certainly have a very strong physician with the U.S. government, but having the additional countries around the world gives us that diversification, which we think is very helpful for us in terms of smoothing out the revenue over time.
Richard Lindahl
Yes. I think the other thing I'd add is that we've provided a range, obviously, of revenue guidance for the full year. And that's the things that are driving that range to one end or the other are the potential for some orders internationally as well as with the U.S. government to materialize this year or in the early part of next year. And then also, there's a range of variability around the ultimate kind of where the naloxone revenues land in the year. So that's what's implied by the range of revenue.
Operator
There are no further questions at this time. I will now turn the call back to Joe Papa for closing remarks.
Joseph Papa
Well, thank you, everyone, for joining today. We very much appreciate the questions as well. We look forward to continuing to work with you and answering your questions, but we appreciate very much your time today. Thank you, everyone. Have a great day.
Operator
This concludes today's call. Thank you for attending. You may now disconnect.
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