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Spyre Therapeutics Inc
SYREAdd to Watchlist
98.330USD
-3.170-3.12%
Close 07-31 16:00（ET）Quotes delayed by 15 min
8.54BMarket Cap
LossP/E TTM
Shareholding Stats
Updated: Mon, May 11
Updated: Mon, May 11
Shareholders
Shareholder Types
Shareholders
Shareholders
Proportion
Fidelity Management & Research Company LLC
13.28%
BlackRock Institutional Trust Company, N.A.
5.75%
Perceptive Advisors LLC
4.97%
RTW Investments L.P.
4.80%
Fairmount Funds Management LLC
4.63%
Other
66.57%
Shareholders
Shareholders
Proportion
Fidelity Management & Research Company LLC
13.28%
BlackRock Institutional Trust Company, N.A.
5.75%
Perceptive Advisors LLC
4.97%
RTW Investments L.P.
4.80%
Fairmount Funds Management LLC
4.63%
Other
66.57%
Shareholder Types
Shareholders
Proportion
Investment Advisor
41.49%
Investment Advisor/Hedge Fund
23.33%
Hedge Fund
18.93%
Venture Capital
6.12%
Individual Investor
5.90%
Private Equity
5.15%
Research Firm
1.00%
Bank and Trust
0.27%
Pension Fund
0.24%
Institutional Shareholding
Updated: Wed, Apr 1
Updated: Wed, Apr 1
Reporting Period
No. of institutions
Shares Held
Proportion
Change
2026Q1
354
88.99M
103.37%
+15.27M
2025Q4
317
66.99M
86.34%
-6.02M
2025Q3
298
65.04M
85.30%
-7.71M
2025Q2
294
72.36M
119.81%
+322.00K
2025Q1
303
71.05M
117.75%
+125.57K
2024Q4
285
66.15M
109.77%
+5.27M
2024Q3
266
53.78M
104.74%
-3.29M
2024Q2
236
52.59M
103.65%
+11.50M
2024Q1
227
33.78M
92.59%
-505.83K
2023Q4
200
30.14M
83.90%
+18.94M
View more
Shareholder Activity
Name
Shares Held
Proportion
Change
Chg %
Date
Fidelity Management & Research Company LLC
11.53M
14.68%
+2.56M
+28.52%
Dec 31, 2025
BlackRock Institutional Trust Company, N.A.
4.99M
6.36%
+1.40M
+39.08%
Dec 31, 2025
Perceptive Advisors LLC
3.07M
3.91%
+1.84M
+149.64%
Dec 31, 2025
RTW Investments L.P.
4.17M
5.31%
+550.00K
+15.18%
Dec 31, 2025
Fairmount Funds Management LLC
4.02M
5.12%
--
--
Dec 31, 2025
VR Adviser, LLC
3.69M
4.69%
+1.00M
+37.24%
Dec 31, 2025
Deutsch (Peter E)
3.55M
4.52%
+3.17M
+825.37%
Oct 14, 2024
Capital International Investors
3.49M
4.45%
+1.10M
+45.98%
Dec 31, 2025
Driehaus Capital Management, LLC
2.88M
3.67%
+822.04K
+39.90%
Dec 31, 2025
View more
Related ETFs
Updated: Sat, Dec 6
Updated: Sat, Dec 6
Name
Proportion
Virtus LifeSci Biotech Clinical Trials ETF
0.94%
State Street SPDR S&P Biotech ETF
0.49%
First Trust Multi-Manager Small Cap Opportunities ETF
0.48%
Optimize Strategy Index ETF
0.32%
ProShares Ultra Nasdaq Biotechnology
0.22%
Direxion Daily S&P Biotech Bull 3X Shares
0.22%
Invesco Nasdaq Biotechnology ETF
0.15%
iShares Biotechnology ETF
0.11%
JPMorgan BetaBuilders US Small Cap Equity ETF
0.08%
iShares Morningstar Small-Cap Value ETF
0.06%
View more
Virtus LifeSci Biotech Clinical Trials ETF
Proportion0.94%
State Street SPDR S&P Biotech ETF
Proportion0.49%
First Trust Multi-Manager Small Cap Opportunities ETF
Proportion0.48%
Optimize Strategy Index ETF
Proportion0.32%
ProShares Ultra Nasdaq Biotechnology
Proportion0.22%
Direxion Daily S&P Biotech Bull 3X Shares
Proportion0.22%
Invesco Nasdaq Biotechnology ETF
Proportion0.15%
iShares Biotechnology ETF
Proportion0.11%
JPMorgan BetaBuilders US Small Cap Equity ETF
Proportion0.08%
iShares Morningstar Small-Cap Value ETF
Proportion0.06%