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Conferencia de resultados del T3 de 2026 de Amarin (AMRN): Vuelve la rentabilidad a medida que crece la demanda internacional

TradingKey28 de oct de 2026 21:51
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Amarin Corporation informó unos ingresos netos en el tercer trimestre de 2026 de 39,6 millones de dólares, reflejando una contracción interanual debida a la presión sobre los precios en EE. UU. No obstante, la compañía registró su primer beneficio neto positivo en dos años, situado en 245.000 dólares, y mantuvo un flujo de caja operativo favorable de 9 millones de dólares. La posición de efectivo ascendió a 324 millones sin deuda. A nivel internacional, la demanda de VAZKEPA en Europa creció un 68%. Clínicamente, el ensayo EMT2 en cáncer colorrectal no alcanzó su criterio principal, pero mostró una reducción del riesgo de muerte del 32%.

Resumen generado por IA

Puntos clave

  • Amarin Corporation (NASDAQ: AMRN) informó de unos ingresos netos en el tercer trimestre de 2026 de 39,6 millones de dólares, por debajo de los 49,7 millones de dólares del tercer trimestre de 2025, ya que la presión sobre los precios en Estados Unidos compensó el volumen estable de VASCEPA de marca.
  • La empresa registró un beneficio neto de 245.000 dólares, o menos de 0,01 dólares por acción, frente a una pérdida neta de 7,7 millones de dólares, o 0,02 dólares por acción, un año antes. Este fue el primer trimestre rentable de Amarin en dos años.
  • El flujo de caja operativo del tercer trimestre fue positivo en 9 millones de dólares. El efectivo y las inversiones alcanzaron los 324 millones de dólares al 30 de septiembre de 2026, lo que supone un aumento de 21 millones de dólares con respecto al cierre de 2025, sin deuda.
  • El impulso internacional se fortaleció: la demanda estimada de VAZKEPA en Europa aumentó un 68% interanual, mientras que la demanda global combinada de socios para VASCEPA subió un 55%.
  • El ensayo de Fase III EMT2 promovido por el investigador no alcanzó su criterio de valoración principal de supervivencia libre de progresión. Sin embargo, VASCEPA produjo un riesgo de muerte estadísticamente significativo un 32% menor en el criterio de valoración secundario clave de supervivencia global.
  • La directiva sigue esperando un flujo de caja operativo positivo para todo el año 2026 y un volumen estable en Estados Unidos hasta finales de año, al tiempo que prevé una presión continuada sobre los precios en Estados Unidos hasta 2027.

Datos financieros clave

MétricaT3 2026T3 2025Comentarios
Ingresos netos totales39,6 millones de $49,7 millones de $Los menores precios netos de venta en Estados Unidos fueron el principal obstáculo
Ingresos por productos36,9 millones de $48,6 millones de $Incluyó ventas en Estados Unidos, Europa y el resto del mundo
Ingresos por licencias y regalías2,7 millones de $1,1 millones de $Aumentó interanualmente
Ingresos por productos en Estados Unidos28,5 millones de $40,9 millones de $El volumen de la marca se mantuvo estable, pero los precios disminuyeron ante la competencia de genéricos
Ingresos por productos en Europa3,7 millones de $4,1 millones de $Las compras de los socios pueden variar según el inventario y los patrones de pedidos
Ingresos por productos en el resto del mundo4,7 millones de $3,6 millones de $Respaldado por la inversión y ejecución de los socios
Coste de los bienes vendidos23,4 millones de $27,5 millones de $Los contratos de suministro renegociados comenzaron a beneficiar los márgenes
Gastos operativos totalesBaja del 44% interanual—Excluyendo los costes de reestructuración, los gastos disminuyeron un 22%
Beneficio/(pérdida) neto/a0,245 millones de $$(7,7) millonesPrimer trimestre rentable en dos años
Flujo de caja operativo9 millones de $—Cuarto trimestre consecutivo de flujo de caja operativo positivo
Flujo de caja operativo de nueve meses22 millones de $$(9) millonesMejora interanual significativa
Efectivo e inversiones324 millones de $—21 millones de dólares más que a finales de 2025; sin deuda

Rendimiento empresarial y operativo

VASCEPA conservó una cuota del 47% en el mercado de icosapento de etilo en Estados Unidos. La directiva señaló que el volumen de recetas de la marca se mantuvo relativamente estable, mientras que los menores precios netos de venta impulsaron la caída interanual de los ingresos. La empresa prevé mantener la exclusividad con los principales pagadores de Estados Unidos hasta finales de 2026.

En Europa, VAZKEPA se comercializaba en 11 países a través de Recordati al 30 de septiembre de 2026. En octubre se produjo el lanzamiento en el sector privado en Polonia. España, el Reino Unido e Italia siguieron siendo los principales contribuidores, mientras que Recordati continuó con los trabajos de fijación de precios, reembolso y comercialización en su territorio de 59 países.

Se estima que la demanda del mercado europeo aumentó un 68% interanual en el tercer trimestre, mientras que la demanda en el resto del mundo se incrementó un 46%. En todo el negocio internacional, la demanda del mercado final de los últimos 12 meses aumentó un 59% estimado en comparación con el período de 12 meses anterior.

Amarin advirtió que las compras de suministro de los socios podrían no evolucionar en paralelo con la demanda del mercado final en un trimestre determinado debido a los niveles de inventario y los calendarios de pedidos. Se están preparando los lanzamientos en Singapur y Corea del Sur para principios de 2027, junto con actividad regulatoria y comercial adicional en el sudeste asiático.

Las renegociaciones de los contratos de suministro contribuyeron a una mejora secuencial del margen bruto de aproximadamente 2,3 puntos porcentuales, excluyendo las depreciaciones de activos. El inventario se ha reducido un 31% desde el cuarto trimestre de 2024, disminuyendo el capital de trabajo inmovilizado en el negocio.

Novedades clínicas y regulatorias

El estudio EMT2 incluyó a 448 pacientes sometidos a resección hepática por metástasis hepáticas de cáncer colorrectal. Los pacientes recibieron VASCEPA o placebo antes de la cirugía y hasta cuatro años después, junto con la atención estándar.

El ensayo no alcanzó su criterio de valoración principal de supervivencia libre de progresión, pero mostró una reducción estadísticamente significativa del 32% en el riesgo de muerte en el criterio de valoración secundario clave de supervivencia global. La directiva enfatizó que los hallazgos siguen siendo en fase de investigación y requieren un análisis más profundo con el grupo de investigación de la Universidad de Leeds antes de que Amarin determine una posible vía de desarrollo u oportunidad comercial.

Por otra parte, el icosapento de etilo fue incluido en las guías europeas recientemente publicadas para el tratamiento de las enfermedades cardiovasculares y la enfermedad renal crónica, desarrolladas junto con la Asociación Renal Europea.

Orientaciones de la directiva

La directiva mantiene sus expectativas de un flujo de caja operativo positivo para todo el año 2026. Se prevé que los volúmenes en Estados Unidos se mantengan estables hasta finales de año, mientras que se espera que los precios se mantengan relativamente constantes debido a que la exclusividad con los pagadores se prolongará hasta 2026.

La empresa no ha publicado previsiones para 2027. Está a la espera de la confirmación de los acuerdos de exclusividad con los pagadores y prevé que la presión sobre los precios en Estados Unidos observada en años anteriores continúe en 2027.

Amarin también está trabajando con Barclays, su asesor financiero exclusivo, en iniciativas orientadas a maximizar el valor para los accionistas. La directiva señaló que el resultado de esas conversaciones influirá en el calendario, la escala y la priorización del posible despliegue de capital, incluida una eventual recompra de acciones.

Riesgos y factores a vigilar

  • La competencia de genéricos sigue presionando los precios netos de venta en Estados Unidos a pesar de la estabilidad del volumen de la marca.
  • La exclusividad con los pagadores de Estados Unidos más allá de 2026 sigue siendo incierta, y la directiva prevé que la presión sobre los precios persista en 2027.
  • Los ingresos por productos internacionales pueden fluctuar debido a que las compras de los socios dependen de los niveles de inventario, la combinación de ventas y el calendario de los pedidos.
  • El margen bruto puede variar según el trimestre en función de los precios en Estados Unidos, la combinación de productos y el momento y volumen de los envíos de suministro internacionales.
  • El estudio EMT2 no cumplió su criterio de valoración principal, y cualquier aplicación oncológica más amplia para VASCEPA requiere análisis adicionales, validación científica y la evaluación de consideraciones comerciales y de propiedad intelectual.

Lo más destacado del turno de preguntas y respuestas de los analistas

Al ser preguntada por la divergencia entre las recetas y los ingresos en Estados Unidos, la directiva afirmó que el volumen de VASCEPA de marca se mantuvo estable y que la caída de los ingresos se debió a la presión sobre los precios.

En cuanto al reembolso en Europa, la directiva destacó el mayor alcance de Recordati en 59 países, el reciente lanzamiento en Polonia y las actividades en curso en Francia. La empresa no facilitó un calendario para decisiones adicionales sobre reembolsos.

Respecto a nuevas aplicaciones terapéuticas, la directiva señaló que evaluará las necesidades no cubiertas, la evidencia existente, el potencial comercial, la protección de la propiedad intelectual y el riesgo de desarrollo. Amarin aún no ha determinado si buscará un socio para ayudar a financiar un posterior desarrollo derivado del estudio EMT2.

Transcripción completa de la llamada de resultados


Transcripción completa de la conferencia de resultados

Comentarios de la dirección

Operator

Greetings, and welcome to the Amarin Corporation's Third Quarter 2026 Results Conference Call. [Operator Instructions] And please note, this conference is being recorded.

I will now turn the conference over to your host, Mr. Devin Sullivan, Investor Relations. Sir, you may begin.

Unknown Executive

Thank you for your time and attention this morning as we discuss Amarin's 2026 Third Quarter Financial Results. On today's call are Aaron Berg, President and Chief Executive Officer; Pete Fishman, Chief Financial Officer; and Steve Ketchum, President of Research and Development and Chief Scientific Officer. Other members of the senior management team will be available as needed during the Q&A session following the prepared remarks.

Aaron will provide a state of the company update. Pete will discuss the numbers, and Steve will review recent medical and regulatory activities. Before we begin, I'd like to remind everyone that today's press release and related quarterly report on Form 10-Q will be available on the Investor Relations section of the company's website, www.amarincorp.com, as well as a replay of this call shortly after its completion.

Please be aware that during this call, we may make certain statements related to our business that are deemed forward-looking statements under federal securities laws. Statements are not guarantees of future performance, but rather are subject to a variety of risks and uncertainties. Our actual results could differ materially from expectations reflected in any forward-looking statements. Additionally, we assume no obligation to update these statements as circumstances change. For a discussion of the material risks and important factors that could affect our actual results, please refer to our SEC filings, which are available either on our company website or the Securities and Exchange Commission's EDGAR system.

With that said, I'd now like to turn the call over to Amarin's President and CEO, Aaron Berg. Aaron, please go ahead.

Aaron Berg

Thanks, Devin, and thank you all for joining us today. As we approach the end of the year, I want to take the opportunity to highlight all that we've achieved, what lies ahead and most importantly, how we continue to hold ourselves accountable to the standard of delivering value to our shareholders. As you can see in our press release, through the hard work of our team, the support of our commercial partners and the enduring clinically validated efficacy of VASCEPA, the momentum we experienced in the first half of 2026 continued through the third quarter across multiple fronts, including profitable third quarter results, reductions in our expense profile, continued positive operating cash flow, a stronger cash position and 0 debt.

Our outlook for the full year remains positive. Our partners are expanding the global reach of VASCEPA and VAZKEPA and driving double-digit in-market demand growth. We've also maintained our U.S. leadership position in a highly competitive IPE space. We also announced exciting news earlier this week regarding clinical trial results, which may further add to our continued work on broadening our understanding of VASCEPA's potential beyond cardiovascular care, and we'll touch on that shortly.

As of September 30, 2026, through our exclusive agreement with Recordati, VAZKEPA was commercialized in 11 countries in Europe. And in October, VAZKEPA launched in Poland on a private pay basis. In-market demand in Europe for VAZKEPA under the Recordati partnership rose by an estimated 68% in Q3 2026 compared to the same period last year. Spain, U.K. and Italy continue to produce strong results, which are helping to build a foundation for future growth as pricing, reimbursement and commercialization efforts continue across the broader territory.

Recordati has been an outstanding partner. While we're still in the early stages of the partnership, their execution and investment are driving momentum materially above historical European growth rates achieved by Amarin prior to the licensing transaction. With the rights to commercialize VAZKEPA across 59 countries, a deep heritage in cardiovascular disease and extensive commercial capabilities throughout Europe, Recordati is unlocking opportunities beyond our reach in a region with substantial untapped potential. Combined with intellectual property protection through 2039, we have a long runway to create value together.

Across our combined global partner network, in-market demand for VASCEPA rose by an estimated 55% in Q3 compared to the same period last year, reflecting continued in-market demand growth. We're continuing to support our local partners in preparation for launches in Singapore and South Korea in early 2027 and with additional regulatory approvals and market launches across Southeast Asia. We maintained our leading position in the U.S. IPE market with a 47% share while continuing to manage the business profitably.

Pricing remains competitive, but our commercial discipline, focus and efficiency continue to support our position. We continue to expect to maintain our exclusivity with key payers through the end of 2026 and expect U.S. volumes to remain stable through year-end. As background, changes in product exclusivity are part of the normal cadence of our U.S. commercial business. At the same time, our strengthened operating infrastructure gives us greater flexibility to be selective as we evaluate opportunities and elect to move forward only when the economics make sense and support our profitability objectives.

I'll now turn the call over to Pete Fishman, our Chief Financial Officer, who will go over our results. Pete?

Peter Fishman

Thanks, Aaron. We reported our first profitable quarter in 2 years, reflecting the benefits of our completed restructuring as well as our company-managed U.S. and fully partnered international commercial model. Our third quarter performance demonstrated continued progress against our core priorities. supporting international end market growth for our partners, maintaining our leadership position in the U.S. IPE market, establishing a significantly lower go-forward cost base and strengthening our overall financial position.

Total net revenue in the third quarter of 2026 was $39.6 million compared to $49.7 million in the third quarter of 2025. This consisted of total product revenue of $36.9 million compared to $48.6 million and licensing and royalty revenue of $2.7 million, up from $1.1 million. U.S. product revenue was $28.5 million compared to $40.9 million in last year's third quarter. The decrease reflected lower net selling prices associated with changes in customer mix, driven largely by generic competition. While pricing remains competitive, continued volume strength, combined with operating efficiencies supported the U.S. business' ongoing profitability and cash generation.

In Europe, third quarter product revenue declined to $3.7 million from $4.1 million under our partner model. Rest of World product revenue rose to $4.7 million from $3.6 million in the prior year period, reflecting continued commercial investment and execution by our partnership network. End-market demand across Europe rose by an estimated 68% from last year's third quarter, with Rest of World in market demand rising an estimated 46%. I'd like to briefly address the relationship between our international product revenue and end market demand.

We are encouraged by the in-market demand growth of VASCEPA VASKEPA across Europe and the rest of the world. In-market demand provides a more direct view of the underlying growth of our international business, and we expect this growth to contribute to increased partner supply purchases and related revenue over time as our partnered international commercial model matures. The timing and level of these purchases will continue to reflect partner inventory levels and ordering patterns and may not grow at the same rate as in-market demand in any given period.

Because partner purchases can vary quarter-to-quarter, we believe a trailing 12-month view provides helpful context alongside quarterly comparisons. On that basis, international end market demand increased an estimated 59% compared with the preceding 12-month period, reflecting sustained growth beyond any single quarter. Over time, we expect international product revenue to be best evaluated on the same basis. Cost of goods sold in the third quarter declined to $23.4 million from $27.5 million in the prior year period.

We use the weighted average cost of our inventory to calculate cost of goods sold, which is influenced by API purchases, U.S. sales volumes and the size and timing of supply shipments to our international partners. Our Q3 results reflect the early benefits of our renegotiated supply contracts, which contributed to a sequential gross margin improvement excluding write-offs of approximately 2.3 percentage points despite continued U.S. pricing pressure. While we expect our cost per unit to decline over time, the benefit will flow through gradually and gross margin may vary from quarter-to-quarter based on sales mix and the timing and volume of partner shipments.

Inventory management remains a high priority, and our reduced inventory levels reflect our commitment to disciplined working capital management that aligns supply levels with demand. For perspective, inventory has declined by 31% from Q4 2024, underscoring our progress in optimizing inventory and reducing the capital tied up in the business, contributing to our improved operating cash flow. Total operating expense declined by 44% from last year's third quarter, driven largely by a 27% decline in SG&A and no restructuring expenses during the quarter compared to $9.4 million last year, while R&D remained stable.

Excluding restructuring costs, total operating expenses declined by 22%, reflecting the lower go-forward cost structure established through our restructuring, which we intend to maintain through continued spending discipline. Net income for the quarter was $245,000 or less than $0.01 per share compared to a net loss of $7.7 million or $0.02 per share in last year's third quarter. We generated positive operating cash flow for the third quarter of $9 million. Through the first 9 months of 2026, operating cash flow totaled $22 million compared to a cash outflow of $9 million during the prior year period. We continue to expect positive operating cash flow for the full year. We ended September with cash and investments of $324 million, an increase of $21 million from year-end 2025 and remain debt-free.

That said, I'll turn things back to Aaron.

Aaron Berg

Thanks, Pete. As our global footprint continues to expand, the work of our medical affairs, regulatory and R&D teams becomes increasingly important. Their efforts have resulted in a total of 28 publications, inclusive of abstracts, posters and articles this year-to-date. Beyond that, these teams provide expertise that supports our commercialization partners worldwide from navigating local regulatory requirements and expanding the evidence base for icOSpineyl to engaging scientific leaders, supporting reimbursement discussions and preparing for successful launches.

Before turning things over to Steve Ketchum, Amarin's Chief Scientific Officer, I want to provide some background on an exciting recent development related to the exploratory use of VASCEPA as an adjunct to standard of care in treating a defined population of colorectal cancer patients. The top line results from the investigator-initiated EPA for metastasis Trial 2 or EMT2 Phase III trial using VASCEPA were presented at this year's European Society for Medical Oncology in Madrid, Spain this past weekend.

Importantly, the investigational medicinal product used in EMT2 was VASCEPA in the same dosage utilized in the landmark REDUCE-IT cardiovascular outcomes trial that produced a 25% relative risk reduction in major adverse cardiovascular events. While these results provide a foundation for exploring the potential role for cospenethyl in cancer care, our focus now is on working with our team to better understand the opportunity and its potential to benefit patients. To provide additional perspective on this trial and more broadly, scientific, medical and regulatory activities supporting our global growth strategy,

I'll now turn the call over to Steve Ketchum. Steve?

Steven Ketchum

Thank you, Aaron. This quarter was marked by several important scientific and medical affairs accomplishments that continue to reinforce the value of Vascepa while expanding our understanding of the broader biology of highly purified EPA. We maintained a strong presence at the European Society of Cardiology Congress, where 5 investigator-led presentations further strengthened the growing body of evidence supporting icosapapentpeethyl.

These presentations included new analyses from REDUCE-IT, mechanistic research exploring the effects of EPA across multiple cardiovascular risk pathways and data evaluating long-term outcomes, treatment adherence, lipoprotein A, coagulation biomarkers and other biological mechanisms that may contribute to the benefits observed with IPE. Importantly, ESC also featured the inclusion of icosapent ethyl within the newly issued guidelines for the management of cardiovascular disease and chronic kidney disease in collaboration with the European Renal Association, reinforcing the role of icosapent ethyl as an evidence-based treatment option for appropriate high-risk patients and underscoring its continued relevance in contemporary cardiovascular care.

Beyond our own data, and as Aaron mentioned, investigators from the University of Leeds and other institutions in the U.K. presented results from the EPA for metastasis Trial 2, or EMT2, this past weekend at the ESMO Congress in Madrid. EMT2 was a randomized, double-blind, placebo-controlled investigator-initiated Phase III study evaluating Vascepa, a highly purified ethyl ester form of EPA as an adjunct to standard of care treatment in patients undergoing liver resection for colorectal cancer liver metastases. The study was sponsored by the University of Leeds and enrolled 448 patients who were randomized to receive either Vascepa or placebo beginning prior to liver surgery and continuing for up to 4 years after liver surgery.

The prespecified and statistically powered key study endpoints were progression-free survival and overall survival. Importantly, while the primary endpoint of progression-free survival was not met, the study demonstrated an improvement in the key secondary endpoint of overall survival. a statistically significant 32% lower hazard of death, which is a meaningful finding in a patient population where up to 60% of patients may experience disease recurrence within 2 years following surgery. These findings represent an important contribution to the scientific understanding of IPE and warrant continued evaluation and discussion by the research community.

Notably, EMT2 utilized the same VASCEPA clinical formulation and dose of icosapent ethyl or IPE used in REDUCE-IT. While cardiovascular disease remains our approved indication and our primary focus, findings from EMT2 add to a growing body of evidence suggesting that IPE may exert broad biological effects across multiple pathways and disease processes. Over the past several years, research has increasingly suggested that EPA may influence mechanisms associated with inflammation, oxidative stress, thrombosis, cellular signaling and vascular biology.

Publications related to omega-3 fatty acid used for colorectal cancer prevention, treatment and/or mechanisms of action have reported several biologically plausible hypotheses, including incorporation of EPA in colonic or colorectal tissue, direct anti-inflammatory or antineoplastic activity of prescription IPE and potential augmentation of host antitumor immune surveillance through effects on the gut microbiome. These potential mechanisms remain investigational and require further analysis from EMT2 and from new research.

Of note, recently, an investigator-initiated mechanistic study from the Massachusetts General Hospital in Boston, Massachusetts as well as other institutions published in the American Journal of Clinical Nutrition in June 2026, found that treatment with Vascepa cosapinephyl substantially increased incorporation of marine omega-3 fatty acids, particularly EPA into colorectal tissue. While much remains to be understood, findings from studies such as REDUCE-IT, the growing body of mechanistic research, IIT research and now EMT2 continue to reinforce the unique and increasingly differentiated profile of highly purified IPE, supporting continued scientific investigation into the broader biological effects of prescription IPE and its potential role in areas of significant unmet medical need.

Looking ahead, we remain committed to advancing the science of IPE through collaboration with leading academic investigators around the world. We have just seen the EMT2 results, and we will continue to collaborate with Professor Ho and the University of Leeds Research Group to further evaluate the data and a path forward for Amarin. We are also excited about the upcoming 2026 American Heart Association Scientific Sessions. -- where investigators will present new data related to lipoprotein A, an area of increasing interest within cardiovascular medicine. More than a decade after REDUCE-IT was initiated, investigators continue to generate new insights into the effects of highly purified IPE.

While many questions remain, the breadth and consistency of the data continue to strengthen our understanding of IicOSapentthyl and its potential impact on human health. With that overview of our scientific progress,

I'll now turn the call back to Aaron.

Aaron Berg

Thanks, Steve. Our third quarter results demonstrate that the transformation of our business is translating into tangible operational and financial benefits. We have expanded our global footprint and look forward to a greater global presence in 2027. With a significantly lower cost base, improving supply economics and disciplined working capital management, we've generated 4 consecutive quarters of positive operating cash flow and strengthened our debt-free balance sheet.

While U.S. pricing pressure and the timing of partner orders continue to influence revenue, growing international in-market demand reinforces the opportunity ahead and the added potential opportunity for VASCEPA reflected in the EMT2 trial results only adds to our optimism. We entered the final quarter of 2026 from a position of strength, focused on sustaining positive cash generation, supporting our partners' growth and building long-term shareholder value. In parallel, the progress we've made in reshaping Amarin has put us in a stronger position than at any point in our recent history to deliver value to our shareholders.

Building on that and guided by a clear mandate to maximize shareholder value, we continue to work closely with Barclays, our exclusive financial adviser and remain focused on working through these efforts in a timely and disciplined manner. These discussions and their potential outcomes will inform the timing, scale and prioritization of future capital deployment activities such as a share repurchase.

And with that, operator, let's open the call to questions from our analysts.

Operator

[Operator Instructions] Our first question today is coming from Jessica Fye with JPMorgan.

Preguntas y respuestas

Jessica Fye

I didn't catch the branded prescription growth that usually comes in the press release this quarter. Can you comment on that? How do we reconcile U.S. script volume growth with the decline in U.S. revenues year-over-year?

Unknown Executive

Jess, thanks for joining us. I appreciate the question. The volume for the branded Vascepa was stable. It was relatively flat. The downward impact on revenue was due to pricing pressure.

Jessica Fye

Okay. And then can you just give us a little bit of a sense about how to think about the U.S. price trajectory over the coming kind of quarters?

Unknown Executive

Yes, I'll turn it over to Pete to address that.

Peter Fishman

Yes. When we look at the U.S. pricing over the rest of this year, as we've talked about, we do expect to maintain our exclusives. So we expect the pricing to remain relatively consistent through the end of this year. While we haven't given guidance on '27, and we are still waiting for final confirmation on how the exclusives will look like going into 2027. We have seen that continued pricing pressure over previous years and would anticipate that to continue into '27.

Operator

Our next question is coming from Paul Choi with Goldman Sachs.

Kyuwon Choi

I wanted to ask on where you're able to comment on any updates in terms of reimbursement and coverage in major European markets. Any additional color there would be helpful. And my second question is in terms of thinking about the additional therapeutic applications for IPE, sort of what criteria are you considering here? And are you looking for a partner to help co-fund future development?

Aaron Berg

Paul, thanks for joining us. Thanks for the questions. Regarding reimbursement in Europe, we've been very encouraged by the approach that Recordati take. As we mentioned, the partnership is for 59 countries. They -- not just focusing on the major markets in Western Europe, but much broader than we at Amarin could have ever executed on our own. So they're making progress beyond where we've already commercialized.

In fact, as we mentioned, they just launched in Poland. It's public that there's activity going on with France, a very lengthy process. We're certainly optimistic and we believe we have the right partner that certainly can advance VAZKEPA well beyond the markets where we're already commercialized. So there's a lot of activity going on. There's a lot going on to explore the potential in certain markets while at the same time, trying to find a way to enter those markets.

As we get more clarity that we can speak to, we'll certainly do that. But we're very pleased and again, in particular, that they are going well beyond where we would have gone as Aron on our own. Regarding the potential other clinical applications. EMT2 certainly brings that question to the forefront. Regarding that, we just saw the data ourselves. We're very excited about that data as should patients because the second most prevalent cause of cancer death, colorectal cancer globally.

So the unmet need is there, and these are very, very sick patients that were studied. We have a lot to learn about the data, and that's what Steve has mentioned is that we'll be working with Dr. Hall as well as the University of Leeds. We'll continue collaborating with them to see where we go at the same time, from a commercial perspective, assessing what value there is for us. And that's the approach we'll take with any other potential therapeutic application.

And that is what's the commercial opportunity, what's the unmet need, what data already exists, what can we do to protect it? A lot of questions that we ask. We're fortunate that we have a molecule that has such broad application, and there's probably more we don't know still about what this drug can do that we do know. And certainly, EMT2 is a testament to that. So once we identify more about which path we go, we'll also identify whether we share in that, how we approach it.

Certainly, we will be very disciplined managing the risk and the opportunity at the same time. But once we know more, we'll certainly report on that. That's a good question. Thank you.

Operator

Apologies if you cannot hear me. Can you hear me?

Aaron Berg

Now we can.

Operator

Ladies and gentlemen, as we have no further questions in the queue at this time, I would like to turn the call back over to Mr. Berg for any closing remarks.

Unknown Executive

Yes. Once again, thank you all very much for joining us. Thanks for your attention to Amarin, and we look forward to keeping you apprised of our progress as we move forward. Thank you. Have a good day.

Operator

Thank you. Ladies and gentlemen, this does conclude today's call. You may disconnect your lines at this time, and we thank you for your participation.

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Advertencia de Riesgo: Nuestro sitio web y aplicación móvil solo proporcionan información general sobre ciertos productos de inversión. Finsights no proporciona, y la provisión de dicha información no debe interpretarse como que Finsights proporciona, asesoramiento financiero o recomendación para cualquier producto de inversión.
Los productos de inversión están sujetos a riesgos de inversión significativos, incluida la posible pérdida del monto principal invertido y pueden no ser adecuados para todos. El rendimiento pasado de los productos de inversión no es indicativo de su rendimiento futuro.
Finsights puede permitir que anunciantes o afiliados de terceros coloquen o entreguen anuncios en nuestro sitio web o aplicación móvil o en cualquier parte de los mismos y puede ser compensado por ellos en función de su interacción con los anuncios.
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